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Items: 1 to 20 of 140


Adaptation of a RAS pathway activation signature from FF to FFPE tissues in colorectal cancer.

Omolo B, Yang M, Lo FY, Schell MJ, Austin S, Howard K, Madan A, Yeatman TJ.

BMC Med Genomics. 2016 Oct 19;9(1):65.


A multigene mutation classification of 468 colorectal cancers reveals a prognostic role for APC.

Schell MJ, Yang M, Teer JK, Lo FY, Madan A, Coppola D, Monteiro AN, Nebozhyn MV, Yue B, Loboda A, Bien-Willner GA, Greenawalt DM, Yeatman TJ.

Nat Commun. 2016 Jun 15;7:11743. doi: 10.1038/ncomms11743.


Adenomatous polyposis coli (APC) regulates miR17-92 cluster through β-catenin pathway in colorectal cancer.

Li Y, Lauriola M, Kim D, Francesconi M, D'Uva G, Shibata D, Malafa MP, Yeatman TJ, Coppola D, Solmi R, Cheng JQ.

Oncogene. 2016 Sep 1;35(35):4558-68. doi: 10.1038/onc.2015.522.


A Composite Gene Expression Signature Optimizes Prediction of Colorectal Cancer Metastasis and Outcome.

Schell MJ, Yang M, Missiaglia E, Delorenzi M, Soneson C, Yue B, Nebozhyn MV, Loboda A, Bloom G, Yeatman TJ.

Clin Cancer Res. 2016 Feb 1;22(3):734-45. doi: 10.1158/1078-0432.CCR-15-0143.


Suppression of Reserve MCM Complexes Chemosensitizes to Gemcitabine and 5-Fluorouracil.

Bryant VL, Elias RM, McCarthy SM, Yeatman TJ, Alexandrow MG.

Mol Cancer Res. 2015 Sep;13(9):1296-305. doi: 10.1158/1541-7786.MCR-14-0464.


Co-evolution of somatic variation in primary and metastatic colorectal cancer may expand biopsy indications in the molecular era.

Kim R, Schell MJ, Teer JK, Greenawalt DM, Yang M, Yeatman TJ.

PLoS One. 2015 May 14;10(5):e0126670. doi: 10.1371/journal.pone.0126670.


MicroRNA-147 induces a mesenchymal-to-epithelial transition (MET) and reverses EGFR inhibitor resistance.

Lee CG, McCarthy S, Gruidl M, Timme C, Yeatman TJ.

PLoS One. 2014 Jan 15;9(1):e84597. doi: 10.1371/journal.pone.0084597.


Gamma-secretase inhibition attenuates oxaliplatin-induced apoptosis through increased Mcl-1 and/or Bcl-xL in human colon cancer cells.

Timme CR, Gruidl M, Yeatman TJ.

Apoptosis. 2013 Oct;18(10):1163-74. doi: 10.1007/s10495-013-0883-x.


Prognostic and predictive value of a malignancy-risk gene signature in early-stage non-small cell lung cancer.

Chen DT, Hsu YL, Fulp WJ, Coppola D, Haura EB, Yeatman TJ, Cress WD.

J Natl Cancer Inst. 2011 Dec 21;103(24):1859-70. doi: 10.1093/jnci/djr420.


Smad4-mediated signaling inhibits intestinal neoplasia by inhibiting expression of β-catenin.

Freeman TJ, Smith JJ, Chen X, Washington MK, Roland JT, Means AL, Eschrich SA, Yeatman TJ, Deane NG, Beauchamp RD.

Gastroenterology. 2012 Mar;142(3):562-571.e2. doi: 10.1053/j.gastro.2011.11.026.


Prognostic gene expression signature associated with two molecularly distinct subtypes of colorectal cancer.

Oh SC, Park YY, Park ES, Lim JY, Kim SM, Kim SB, Kim J, Kim SC, Chu IS, Smith JJ, Beauchamp RD, Yeatman TJ, Kopetz S, Lee JS.

Gut. 2012 Sep;61(9):1291-8. doi: 10.1136/gutjnl-2011-300812.


BVES regulates EMT in human corneal and colon cancer cells and is silenced via promoter methylation in human colorectal carcinoma.

Williams CS, Zhang B, Smith JJ, Jayagopal A, Barrett CW, Pino C, Russ P, Presley SH, Peng D, Rosenblatt DO, Haselton FR, Yang JL, Washington MK, Chen X, Eschrich S, Yeatman TJ, El-Rifai W, Beauchamp RD, Chang MS.

J Clin Invest. 2011 Oct;121(10):4056-69. doi: 10.1172/JCI44228.


Claudin-1 up-regulates the repressor ZEB-1 to inhibit E-cadherin expression in colon cancer cells.

Singh AB, Sharma A, Smith JJ, Krishnan M, Chen X, Eschrich S, Washington MK, Yeatman TJ, Beauchamp RD, Dhawan P.

Gastroenterology. 2011 Dec;141(6):2140-53. doi: 10.1053/j.gastro.2011.08.038.


Palladin is a marker of liver metastasis in primary pancreatic endocrine carcinomas.

Henderson-Jackson EB, Helm J, Strosberg J, Nasir NA, Yeatman TJ, Kvols LK, Coppola D, Nasir A.

Anticancer Res. 2011 Sep;31(9):2957-62.


Expression of the antiapoptotic protein survivin in colon cancer.

Hernandez JM, Farma JM, Coppola D, Hakam A, Fulp WJ, Chen DT, Siegel EM, Yeatman TJ, Shibata D.

Clin Colorectal Cancer. 2011 Sep;10(3):188-93. doi: 10.1016/j.clcc.2011.03.014.


Novel molecular markers of malignancy in histologically normal and benign breast.

Nasir A, Chen DT, Gruidl M, Henderson-Jackson EB, Venkataramu C, McCarthy SM, McBride HL, Harris E, Khakpour N, Yeatman TJ.

Patholog Res Int. 2011;2011:489064. doi: 10.4061/2011/489064.


RUNX1T1: a novel predictor of liver metastasis in primary pancreatic endocrine neoplasms.

Nasir A, Helm J, Turner L, Chen DT, Strosberg J, Hafez N, Henderson-Jackson EB, Hodul P, Bui MM, Nasir NA, Hakam A, Malafa MP, Yeatman TJ, Coppola D, Kvols LK.

Pancreas. 2011 May;40(4):627-33. doi: 10.1097/MPA.0b013e3182152bda.


Claudin-2 expression increases tumorigenicity of colon cancer cells: role of epidermal growth factor receptor activation.

Dhawan P, Ahmad R, Chaturvedi R, Smith JJ, Midha R, Mittal MK, Krishnan M, Chen X, Eschrich S, Yeatman TJ, Harris RC, Washington MK, Wilson KT, Beauchamp RD, Singh AB.

Oncogene. 2011 Jul 21;30(29):3234-47. doi: 10.1038/onc.2011.43.


EMT is the dominant program in human colon cancer.

Loboda A, Nebozhyn MV, Watters JW, Buser CA, Shaw PM, Huang PS, Van't Veer L, Tollenaar RA, Jackson DB, Agrawal D, Dai H, Yeatman TJ.

BMC Med Genomics. 2011 Jan 20;4:9. doi: 10.1186/1755-8794-4-9.


The 2010 Health Care Reform Act: a potential opportunity to advance cancer research by taking cancer personally.

Dalton WS, Sullivan DM, Yeatman TJ, Fenstermacher DA.

Clin Cancer Res. 2010 Dec 15;16(24):5987-96. doi: 10.1158/1078-0432.CCR-10-1216. Review.

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