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Items: 1 to 20 of 75

1.

TBK1 Suppresses RIPK1-Driven Apoptosis and Inflammation during Development and in Aging.

Xu D, Jin T, Zhu H, Chen H, Ofengeim D, Zou C, Mifflin L, Pan L, Amin P, Li W, Shan B, Naito MG, Meng H, Li Y, Pan H, Aron L, Adiconis X, Levin JZ, Yankner BA, Yuan J.

Cell. 2018 Sep 6;174(6):1477-1491.e19. doi: 10.1016/j.cell.2018.07.041. Epub 2018 Aug 23.

PMID:
30146158
2.

APOE4 Causes Widespread Molecular and Cellular Alterations Associated with Alzheimer's Disease Phenotypes in Human iPSC-Derived Brain Cell Types.

Lin YT, Seo J, Gao F, Feldman HM, Wen HL, Penney J, Cam HP, Gjoneska E, Raja WK, Cheng J, Rueda R, Kritskiy O, Abdurrob F, Peng Z, Milo B, Yu CJ, Elmsaouri S, Dey D, Ko T, Yankner BA, Tsai LH.

Neuron. 2018 Jun 27;98(6):1294. doi: 10.1016/j.neuron.2018.06.011. No abstract available.

3.

APOE4 Causes Widespread Molecular and Cellular Alterations Associated with Alzheimer's Disease Phenotypes in Human iPSC-Derived Brain Cell Types.

Lin YT, Seo J, Gao F, Feldman HM, Wen HL, Penney J, Cam HP, Gjoneska E, Raja WK, Cheng J, Rueda R, Kritskiy O, Abdurrob F, Peng Z, Milo B, Yu CJ, Elmsaouri S, Dey D, Ko T, Yankner BA, Tsai LH.

Neuron. 2018 Jun 27;98(6):1141-1154.e7. doi: 10.1016/j.neuron.2018.05.008. Epub 2018 May 31. Erratum in: Neuron. 2018 Jun 27;98 (6):1294.

PMID:
29861287
4.

Slowing Down Aging.

Meyer K, Yankner BA.

Cell Metab. 2017 Oct 3;26(4):592-593. doi: 10.1016/j.cmet.2017.09.012.

5.

Neurodegenerative disorders: Neural synchronization in Alzheimer's disease.

Aron L, Yankner BA.

Nature. 2016 Dec 7;540(7632):207-208. doi: 10.1038/540207a. No abstract available.

PMID:
27929001
6.

Addendum: REST and stress resistance in ageing and Alzheimer's disease.

Lu T, Aron L, Zullo J, Pan Y, Kim H, Chen Y, Yang TH, Kim HM, Drake D, Liu XS, Bennett DA, Colaiácovo MP, Yankner BA.

Nature. 2016 Dec 15;540(7633):470. doi: 10.1038/nature20579. Epub 2016 Nov 16. No abstract available.

PMID:
27851730
7.

Sorting Out Presenilins in Alzheimer's Disease.

Wolfe MS, Yankner BA.

Cell. 2016 Jun 30;166(1):13-5. doi: 10.1016/j.cell.2016.06.034.

8.

The DNA damage response induces inflammation and senescence by inhibiting autophagy of GATA4.

Kang C, Xu Q, Martin TD, Li MZ, Demaria M, Aron L, Lu T, Yankner BA, Campisi J, Elledge SJ.

Science. 2015 Sep 25;349(6255):aaa5612. doi: 10.1126/science.aaa5612.

9.

REST and Alzheimer disease.

Yankner BA.

Ann Neurol. 2015 Sep;78(3):499. doi: 10.1002/ana.24420. Epub 2015 May 25. No abstract available.

PMID:
25895068
10.

REST and stress resistance in ageing and Alzheimer's disease.

Lu T, Aron L, Zullo J, Pan Y, Kim H, Chen Y, Yang TH, Kim HM, Drake D, Liu XS, Bennett DA, Colaiácovo MP, Yankner BA.

Nature. 2014 Mar 27;507(7493):448-54. doi: 10.1038/nature13163. Epub 2014 Mar 19. Update in: Nature. 2016 Dec 15;540(7633):470.

11.

Physiology: Inflammation links ageing to the brain.

Gabuzda D, Yankner BA.

Nature. 2013 May 9;497(7448):197-8. doi: 10.1038/nature12100. Epub 2013 May 1. No abstract available.

12.

Altered social behavior and neuronal development in mice lacking the Uba6-Use1 ubiquitin transfer system.

Lee PC, Dodart JC, Aron L, Finley LW, Bronson RT, Haigis MC, Yankner BA, Harper JW.

Mol Cell. 2013 Apr 25;50(2):172-84. doi: 10.1016/j.molcel.2013.02.014. Epub 2013 Mar 14.

13.

Sustained axon regeneration induced by co-deletion of PTEN and SOCS3.

Sun F, Park KK, Belin S, Wang D, Lu T, Chen G, Zhang K, Yeung C, Feng G, Yankner BA, He Z.

Nature. 2011 Nov 6;480(7377):372-5. doi: 10.1038/nature10594.

14.

The aging stress response.

Haigis MC, Yankner BA.

Mol Cell. 2010 Oct 22;40(2):333-44. doi: 10.1016/j.molcel.2010.10.002. Review.

15.

Genome-wide analysis reveals mechanisms modulating autophagy in normal brain aging and in Alzheimer's disease.

Lipinski MM, Zheng B, Lu T, Yan Z, Py BF, Ng A, Xavier RJ, Li C, Yankner BA, Scherzer CR, Yuan J.

Proc Natl Acad Sci U S A. 2010 Aug 10;107(32):14164-9. doi: 10.1073/pnas.1009485107. Epub 2010 Jul 26.

16.

Neural mechanisms of ageing and cognitive decline.

Bishop NA, Lu T, Yankner BA.

Nature. 2010 Mar 25;464(7288):529-35. doi: 10.1038/nature08983. Review.

17.

SIRT1 redistribution on chromatin promotes genomic stability but alters gene expression during aging.

Oberdoerffer P, Michan S, McVay M, Mostoslavsky R, Vann J, Park SK, Hartlerode A, Stegmuller J, Hafner A, Loerch P, Wright SM, Mills KD, Bonni A, Yankner BA, Scully R, Prolla TA, Alt FW, Sinclair DA.

Cell. 2008 Nov 28;135(5):907-18. doi: 10.1016/j.cell.2008.10.025.

18.

Amyloid beta-protein toxicity and the pathogenesis of Alzheimer disease.

Yankner BA, Lu T.

J Biol Chem. 2009 Feb 20;284(8):4755-9. doi: 10.1074/jbc.R800018200. Epub 2008 Oct 28. Review. No abstract available.

19.

Evolution of the aging brain transcriptome and synaptic regulation.

Loerch PM, Lu T, Dakin KA, Vann JM, Isaacs A, Geula C, Wang J, Pan Y, Gabuzda DH, Li C, Prolla TA, Yankner BA.

PLoS One. 2008 Oct 2;3(10):e3329. doi: 10.1371/journal.pone.0003329.

20.

Synaptic NMDA receptor activity boosts intrinsic antioxidant defenses.

Papadia S, Soriano FX, Léveillé F, Martel MA, Dakin KA, Hansen HH, Kaindl A, Sifringer M, Fowler J, Stefovska V, McKenzie G, Craigon M, Corriveau R, Ghazal P, Horsburgh K, Yankner BA, Wyllie DJ, Ikonomidou C, Hardingham GE.

Nat Neurosci. 2008 Apr;11(4):476-87. doi: 10.1038/nn2071. Epub 2008 Mar 23.

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