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Items: 1 to 20 of 258

1.

The Prenylflavonoid Xanthohumol Reduces Alzheimer-Like Changes and Modulates Multiple Pathogenic Molecular Pathways in the Neuro2a/APPswe Cell Model of AD.

Huang X, Wang J, Chen X, Liu P, Wang S, Song F, Zhang Z, Zhu F, Huang X, Liu J, Song G, Spencer PS, Yang X.

Front Pharmacol. 2018 Apr 4;9:199. doi: 10.3389/fphar.2018.00199. eCollection 2018.

2.

The hop-derived compounds xanthohumol, isoxanthohumol and 8-prenylnaringenin are tight-binding inhibitors of human aldo-keto reductases 1B1 and 1B10.

Seliger JM, Misuri L, Maser E, Hintzpeter J.

J Enzyme Inhib Med Chem. 2018 Dec;33(1):607-614. doi: 10.1080/14756366.2018.1437728.

3.

Xanthohumol ameliorates 2,3,7,8-tetrachlorodibenzo-p-dioxin-induced cellular toxicity in cultured MC3T3-E1 osteoblastic cells.

Suh KS, Choi EM, Kim HS, Park SY, Chin SO, Rhee SY, Pak YK, Choe W, Ha J, Chon S.

J Appl Toxicol. 2018 Jul;38(7):1036-1046. doi: 10.1002/jat.3613. Epub 2018 Mar 8.

PMID:
29516522
4.

Recombinant expression, purification and biochemical characterization of kievitone hydratase from Nectria haematococca.

Engleder M, Horvat M, Emmerstorfer-Augustin A, Wriessnegger T, Gabriel S, Strohmeier G, Weber H, Müller M, Kaluzna I, Mink D, Schürmann M, Pichler H.

PLoS One. 2018 Feb 8;13(2):e0192653. doi: 10.1371/journal.pone.0192653. eCollection 2018.

5.

Non-estrogenic Xanthohumol Derivatives Mitigate Insulin Resistance and Cognitive Impairment in High-Fat Diet-induced Obese Mice.

Miranda CL, Johnson LA, de Montgolfier O, Elias VD, Ullrich LS, Hay JJ, Paraiso IL, Choi J, Reed RL, Revel JS, Kioussi C, Bobe G, Iwaniec UT, Turner RT, Katzenellenbogen BS, Katzenellenbogen JA, Blakemore PR, Gombart AF, Maier CS, Raber J, Stevens JF.

Sci Rep. 2018 Jan 12;8(1):613. doi: 10.1038/s41598-017-18992-6.

6.

Xanthohumol inhibits angiogenesis by suppressing nuclear factor-κB activation in pancreatic cancer.

Saito K, Matsuo Y, Imafuji H, Okubo T, Maeda Y, Sato T, Shamoto T, Tsuboi K, Morimoto M, Takahashi H, Ishiguro H, Takiguchi S.

Cancer Sci. 2018 Jan;109(1):132-140. doi: 10.1111/cas.13441. Epub 2017 Dec 3.

7.

Hop Phytochemicals and Their Potential Role in Metabolic Syndrome Prevention and Therapy.

Dostálek P, Karabín M, Jelínek L.

Molecules. 2017 Oct 19;22(10). pii: E1761. doi: 10.3390/molecules22101761. Review.

8.

Total synthesis of [13 C]2 -, [13 C]3 -, and [13 C]5 -isotopomers of xanthohumol, the principal prenylflavonoid from hops.

Ellinwood DC, El-Mansy MF, Plagmann LS, Stevens JF, Maier CS, Gombart AF, Blakemore PR.

J Labelled Comp Radiopharm. 2017 Dec;60(14):639-648. doi: 10.1002/jlcr.3571. Epub 2017 Nov 20.

PMID:
28984993
9.

Strong antimicrobial activity of xanthohumol and other derivatives from hops (Humulus lupulus L.) on gut anaerobic bacteria.

Cermak P, Olsovska J, Mikyska A, Dusek M, Kadleckova Z, Vanicek J, Nyc O, Sigler K, Bostikova V, Bostik P.

APMIS. 2017 Nov;125(11):1033-1038. doi: 10.1111/apm.12747. Epub 2017 Sep 28.

PMID:
28960474
10.

Protective effect of xanthohumol against age-related brain damage.

Rancán L, Paredes SD, García I, Muñoz P, García C, López de Hontanar G, de la Fuente M, Vara E, Tresguerres JAF.

J Nutr Biochem. 2017 Nov;49:133-140. doi: 10.1016/j.jnutbio.2017.07.011. Epub 2017 Jul 27.

PMID:
28950154
11.

Cytoprotective effects of xanthohumol against methylglyoxal-induced cytotoxicity in MC3T3-E1 osteoblastic cells.

Suh KS, Chon S, Choi EM.

J Appl Toxicol. 2018 Feb;38(2):180-192. doi: 10.1002/jat.3521. Epub 2017 Sep 20.

PMID:
28940469
12.

Discovery of new MD2-targeted anti-inflammatory compounds for the treatment of sepsis and acute lung injury.

Chen G, Xiao B, Chen L, Bai B, Zhang Y, Xu Z, Fu L, Liu Z, Li X, Zhao Y, Liang G.

Eur J Med Chem. 2017 Oct 20;139:726-740. doi: 10.1016/j.ejmech.2017.08.036. Epub 2017 Aug 24.

PMID:
28858767
13.

DESIGNER Extracts as Tools to Balance Estrogenic and Chemopreventive Activities of Botanicals for Women's Health.

Dietz BM, Chen SN, Alvarenga RFR, Dong H, Nikolić D, Biendl M, van Breemen RB, Bolton JL, Pauli GF.

J Nat Prod. 2017 Aug 25;80(8):2284-2294. doi: 10.1021/acs.jnatprod.7b00284. Epub 2017 Aug 16.

14.

Xanthohumol Suppresses Mylip/Idol Gene Expression and Modulates LDLR Abundance and Activity in HepG2 Cells.

Chen SF, Chen PY, Hsu HJ, Wu MJ, Yen JH.

J Agric Food Chem. 2017 Sep 13;65(36):7908-7918. doi: 10.1021/acs.jafc.7b02282. Epub 2017 Aug 28.

PMID:
28812343
15.

The Influence of Glycosylation of Natural and Synthetic Prenylated Flavonoids on Binding to Human Serum Albumin and Inhibition of Cyclooxygenases COX-1 and COX-2.

Tronina T, Strugała P, Popłoński J, Włoch A, Sordon S, Bartmańska A, Huszcza E.

Molecules. 2017 Jul 21;22(7). pii: E1230. doi: 10.3390/molecules22071230.

16.

Synthesis and antiangiogenic activity study of new hop chalcone Xanthohumol analogues.

Nuti E, Bassani B, Camodeca C, Rosalia L, Cantelmo A, Gallo C, Baci D, Bruno A, Orlandini E, Nencetti S, Noonan DM, Albini A, Rossello A.

Eur J Med Chem. 2017 Sep 29;138:890-899. doi: 10.1016/j.ejmech.2017.07.024. Epub 2017 Jul 17.

PMID:
28750311
17.

Xanthohumol Restores Hepatic Glucolipid Metabolism Balance in Type 1 Diabetic Wistar Rats.

Lima-Fontes M, Costa R, Rodrigues I, Soares R.

J Agric Food Chem. 2017 Aug 30;65(34):7433-7439. doi: 10.1021/acs.jafc.7b02595. Epub 2017 Aug 18.

PMID:
28745504
18.

Effect of Valerian/Hop Mixture on Sleep-Related Behaviors in Drosophila melanogaster.

Choi HS, Ko BS, Kim HD, Hong KB, Suh HJ.

Biol Pharm Bull. 2017;40(7):1101-1110. doi: 10.1248/bpb.b17-00262.

19.

Xanthohumol Blocks Proliferation and Migration of Vascular Smooth Muscle Cells in Vitro and Reduces Neointima Formation in Vivo.

Liu R, Heiss EH, Schachner D, Jiang B, Liu W, Breuss JM, Dirsch VM, Atanasov AG.

J Nat Prod. 2017 Jul 28;80(7):2146-2150. doi: 10.1021/acs.jnatprod.7b00268. Epub 2017 Jun 19.

20.

The role of chalcones: helichrysetin, xanthohumol, and flavokawin-C in promoting neurite outgrowth in PC12 Adh cells.

Phan CW, Sabaratnam V, Yong WK, Abd Malek SN.

Nat Prod Res. 2018 May;32(10):1229-1233. doi: 10.1080/14786419.2017.1331226. Epub 2017 May 25.

PMID:
28539058

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