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Items: 1 to 20 of 29


Identification of C3b-Binding Small-Molecule Complement Inhibitors Using Cheminformatics.

Garcia BL, Skaff DA, Chatterjee A, Hanning A, Walker JK, Wyckoff GJ, Geisbrecht BV.

J Immunol. 2017 May 1;198(9):3705-3718. doi: 10.4049/jimmunol.1601932. Epub 2017 Mar 15.


Co-option of bacteriophage lysozyme genes by bivalve genomes.

Ren Q, Wang C, Jin M, Lan J, Ye T, Hui K, Tan J, Wang Z, Wyckoff GJ, Wang W, Han GZ.

Open Biol. 2017 Jan;7(1). pii: 160285. doi: 10.1098/rsob.160285.


Genome-Wide Convergence during Evolution of Mangroves from Woody Plants.

Xu S, He Z, Guo Z, Zhang Z, Wyckoff GJ, Greenberg A, Wu CI, Shi S.

Mol Biol Evol. 2017 Apr 1;34(4):1008-1015. doi: 10.1093/molbev/msw277.


A One Health overview, facilitating advances in comparative medicine and translational research.

Stroud C, Dmitriev I, Kashentseva E, Bryan JN, Curiel DT, Rindt H, Reinero C, Henry CJ, Bergman PJ, Mason NJ, Gnanandarajah JS, Engiles JB, Gray F, Laughlin D, Gaurnier-Hausser A, Wallecha A, Huebner M, Paterson Y, O'Connor D, Treml LS, Stannard JP, Cook JL, Jacobs M, Wyckoff GJ, Likins L, Sabbagh U, Skaff A, Guloy AS, Hays HD, LeBlanc AK, Coates JR, Katz ML, Lyons LA, Johnson GC, Johnson GS, O'Brien DP, Duan D, Calvet JP, Gandolfi B, Baron DA, Weiss ML, Webster DA, Karanu FN, Robb EJ, Harman RJ.

Clin Transl Med. 2016 Aug;5(Suppl 1):26. doi: 10.1186/s40169-016-0107-4.


Identification and Evolutionary Analysis of Potential Candidate Genes in a Human Eating Disorder.

Sabbagh U, Mullegama S, Wyckoff GJ.

Biomed Res Int. 2016;2016:7281732. doi: 10.1155/2016/7281732. Epub 2016 Mar 21.


Inhibition of bacterial mevalonate diphosphate decarboxylase by eriochrome compounds.

Skaff DA, McWhorter WJ, Geisbrecht BV, Wyckoff GJ, Miziorko HM.

Arch Biochem Biophys. 2015 Jan 15;566:1-6. doi: 10.1016/ Epub 2014 Dec 11.


Identification in Haloferax volcanii of phosphomevalonate decarboxylase and isopentenyl phosphate kinase as catalysts of the terminal enzyme reactions in an archaeal alternate mevalonate pathway.

Vannice JC, Skaff DA, Keightley A, Addo JK, Wyckoff GJ, Miziorko HM.

J Bacteriol. 2014 Mar;196(5):1055-63. doi: 10.1128/JB.01230-13. Epub 2013 Dec 27.


Evolutionary history and genome organization of DUF1220 protein domains.

O'Bleness MS, Dickens CM, Dumas LJ, Kehrer-Sawatzki H, Wyckoff GJ, Sikela JM.

G3 (Bethesda). 2012 Sep;2(9):977-86. doi: 10.1534/g3.112.003061. Epub 2012 Sep 1.


The structures of coiled-coil domains from type III secretion system translocators reveal homology to pore-forming toxins.

Barta ML, Dickenson NE, Patil M, Keightley A, Wyckoff GJ, Picking WD, Picking WL, Geisbrecht BV.

J Mol Biol. 2012 Apr 13;417(5):395-405. doi: 10.1016/j.jmb.2012.01.026. Epub 2012 Feb 1.


ChemVassa: A New Method for Identifying Small Molecule Hits in Drug Discovery.

Moldover B, Solidar A, Montgomery C, Miziorko H, Murphy J, Wyckoff GJ.

Open Med Chem J. 2012;6:29-34. doi: 10.2174/1874104501206010029. Epub 2012 Nov 30.


Detection of selection utilizing molecular phylogenetics: a possible approach.

Yang M, Wyckoff GJ.

Genetica. 2011 May;139(5):639-48. doi: 10.1007/s10709-011-9560-6. Epub 2011 Mar 13.


Phosphatidylinositol transfer proteins: sequence motifs in structural and evolutionary analyses.

Wyckoff GJ, Solidar A, Yoden MD.

J Biomed Sci Eng. 2010 Jan;3(1):65-77. Epub 2010 Jan 12.


Examining Trichophyton tonsurans genotype and biochemical phenotype as determinants of disease severity in tinea capitis.

Abdel-Rahman SM, Talib N, Solidar A, Nopper AJ, Wyckoff GJ.

Med Mycol. 2008 May;46(3):217-23. doi: 10.1080/13693780701787840.


CrossSearch, a user-friendly search engine for detecting chemically cross-linked peptides in conjugated proteins.

Nadeau OW, Wyckoff GJ, Paschall JE, Artigues A, Sage J, Villar MT, Carlson GM.

Mol Cell Proteomics. 2008 Apr;7(4):739-49. doi: 10.1074/mcp.M800020-MCP200. Epub 2008 Feb 16.


Virtual polymorphism: finding divergent peptide matches in mass spectrometry data.

Starkweather R, Barnes CS, Wyckoff GJ, Keightley JA.

Anal Chem. 2007 Jul 1;79(13):5030-9. Epub 2007 May 24.


Evidence for the location of the allosteric activation switch in the multisubunit phosphorylase kinase complex from mass spectrometric identification of chemically crosslinked peptides.

Nadeau OW, Anderson DW, Yang Q, Artigues A, Paschall JE, Wyckoff GJ, McClintock JL, Carlson GM.

J Mol Biol. 2007 Feb 2;365(5):1429-45. Epub 2006 Oct 21.


SPEED: a molecular-evolution-based database of mammalian orthologous groups.

Vallender EJ, Paschall JE, Malcom CM, Lahn BT, Wyckoff GJ.

Bioinformatics. 2006 Nov 15;22(22):2835-7. Epub 2006 Sep 11.


Human lineage-specific amplification, selection, and neuronal expression of DUF1220 domains.

Popesco MC, Maclaren EJ, Hopkins J, Dumas L, Cox M, Meltesen L, McGavran L, Wyckoff GJ, Sikela JM.

Science. 2006 Sep 1;313(5791):1304-7.


A highly unexpected strong correlation between fixation probability of nonsynonymous mutations and mutation rate.

Wyckoff GJ, Malcom CM, Vallender EJ, Lahn BT.

Trends Genet. 2005 Jul;21(7):381-5.


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