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The Type B Flagellin of Hypervirulent Clostridium difficile is Modified with Novel Sulphonated Peptidylamido-Glycans.

Bouché L, Panico M, Hitchen P, Binet D, Sastre F, Faulds-Pain A, Valiente E, Vinogradov E, Aubry A, Fulton K, Twine S, Logan SM, Wren BW, Dell A, Morris HR.

J Biol Chem. 2016 Oct 7. pii: jbc.M116.749481.


Role of glycosyltransferases modifying type B flagellin of emerging hypervirulent Clostridium difficile lineages and their impact on motility and biofilm formation.

Valiente E, Bouché L, Hitchen P, Faulds-Pain A, Songane M, Dawson LF, Donahue E, Stabler RA, Panico M, Morris HR, Bajaj-Elliott M, Logan SM, Dell A, Wren BW.

J Biol Chem. 2016 Oct 4. pii: jbc.M116.749523.


Actinobacillus pleuropneumoniae serovar 8 predominates in England and Wales.

Li Y, Bossé JT, Williamson SM, Maskell DJ, Tucker AW, Wren BW, Rycroft AN, Langford PR; BRADP1T Consortium.

Vet Rec. 2016 Sep 17;179(11):276. doi: 10.1136/vr.103820. Epub 2016 Aug 16. No abstract available.


Characterization of enteropathogenic Escherichia coli of clinical origin from the pediatric population in Pakistan.

Younas M, Siddiqui F, Noreen Z, Bokhari SS, Gomez-Duarte OG, Wren BW, Bokhari H.

Trans R Soc Trop Med Hyg. 2016 Jul;110(7):414-20. doi: 10.1093/trstmh/trw047.


Phenotypic and genotypic characterization of enteroaggregative Escherichia coli isolates from pediatric population in Pakistan.

Khalil U, Younus M, Asghar N, Siddiqui F, Gómez-Duarte OG, Wren BW, Bokhari H.

APMIS. 2016 Oct;124(10):872-80. doi: 10.1111/apm.12577. Epub 2016 Aug 2.


ICEApl1, an Integrative Conjugative Element Related to ICEHin1056, Identified in the Pig Pathogen Actinobacillus pleuropneumoniae.

Bossé JT, Li Y, Fernandez Crespo R, Chaudhuri RR, Rogers J, Holden MT, Maskell DJ, Tucker AW, Wren BW, Rycroft AN, Langford PR; Consortium TB.

Front Microbiol. 2016 Jun 15;7:810. doi: 10.3389/fmicb.2016.00810. eCollection 2016.


Infection Susceptibility in Gastric Intrinsic Factor (Vitamin B12)-Defective Mice Is Subject to Maternal Influences.

Mottram L, Speak AO, Selek RM, Cambridge EL, McIntyre Z, Kane L, Mukhopadhyay S, Grove C, Colin A, Brandt C, Duque-Correa MA, Forbester J, Nguyen TA, Hale C, Vasilliou GS, Arends MJ, Wren BW, Dougan G, Clare S.

MBio. 2016 Jun 21;7(3). pii: e00830-16. doi: 10.1128/mBio.00830-16.


The induction and identification of novel Colistin resistance mutations in Acinetobacter baumannii and their implications.

Thi Khanh Nhu N, Riordan DW, Do Hoang Nhu T, Thanh DP, Thwaites G, Huong Lan NP, Wren BW, Baker S, Stabler RA.

Sci Rep. 2016 Jun 22;6:28291. doi: 10.1038/srep28291.


All Yersinia enterocolitica are pathogenic: virulence of phylogroup 1 Y. enterocolitica in a Galleria mellonella infection model.

Alenizi D, Ringwood T, Redhwan A, Bouraha B, Wren BW, Prentice M, McNally A.

Microbiology. 2016 Aug;162(8):1379-87. doi: 10.1099/mic.0.000311. Epub 2016 May 24.


Recombinant expression of Streptococcus pneumoniae capsular polysaccharides in Escherichia coli.

Kay EJ, Yates LE, Terra VS, Cuccui J, Wren BW.

Open Biol. 2016 Apr 13;6(4):150243. doi: 10.1098/rsob.150243. eCollection 2016 Apr.


'Add, stir and reduce': Yersinia spp. as model bacteria for pathogen evolution.

McNally A, Thomson NR, Reuter S, Wren BW.

Nat Rev Microbiol. 2016 Mar;14(3):177-90. doi: 10.1038/nrmicro.2015.29. Review.


A Phylogenetic and Phenotypic Analysis of Salmonella enterica Serovar Weltevreden, an Emerging Agent of Diarrheal Disease in Tropical Regions.

Makendi C, Page AJ, Wren BW, Le Thi Phuong T, Clare S, Hale C, Goulding D, Klemm EJ, Pickard D, Okoro C, Hunt M, Thompson CN, Phu Huong Lan N, Tran Do Hoang N, Thwaites GE, Le Hello S, Brisabois A, Weill FX, Baker S, Dougan G.

PLoS Negl Trop Dis. 2016 Feb 11;10(2):e0004446. doi: 10.1371/journal.pntd.0004446. eCollection 2016 Feb.


Complete Genome Sequence of MIDG2331, a Genetically Tractable Serovar 8 Clinical Isolate of Actinobacillus pleuropneumoniae.

Bossé JT, Chaudhuri RR, Li Y, Leanse LG, Fernandez Crespo R, Coupland P, Holden MT, Bazzolli DM, Maskell DJ, Tucker AW, Wren BW, Rycroft AN, Langford PR.

Genome Announc. 2016 Jan 28;4(1). pii: e01667-15. doi: 10.1128/genomeA.01667-15.


Intracellular replication of the well-armed pathogen Burkholderia pseudomallei.

Willcocks SJ, Denman CC, Atkins HS, Wren BW.

Curr Opin Microbiol. 2016 Feb;29:94-103. doi: 10.1016/j.mib.2015.11.007. Epub 2016 Jan 22. Review.


Characterization of New Virulence Factors Involved in the Intracellular Growth and Survival of Burkholderia pseudomallei.

Moule MG, Spink N, Willcocks S, Lim J, Guerra-Assunção JA, Cia F, Champion OL, Senior NJ, Atkins HS, Clark T, Bancroft GJ, Cuccui J, Wren BW.

Infect Immun. 2015 Dec 28;84(3):701-10. doi: 10.1128/IAI.01102-15.


Genome-Based Infection Tracking Reveals Dynamics of Clostridium difficile Transmission and Disease Recurrence.

Kumar N, Miyajima F, He M, Roberts P, Swale A, Ellison L, Pickard D, Smith G, Molyneux R, Dougan G, Parkhill J, Wren BW, Parry CM, Pirmohamed M, Lawley TD.

Clin Infect Dis. 2016 Mar 15;62(6):746-52. doi: 10.1093/cid/civ1031. Epub 2015 Dec 18.


Functional analysis of N-linking oligosaccharyl transferase enzymes encoded by deep-sea vent proteobacteria.

Mills DC, Jervis AJ, Abouelhadid S, Yates LE, Cuccui J, Linton D, Wren BW.

Glycobiology. 2016 Apr;26(4):398-409. doi: 10.1093/glycob/cwv111. Epub 2015 Nov 26.


Whole genome investigation of a divergent clade of the pathogen Streptococcus suis.

Baig A, Weinert LA, Peters SE, Howell KJ, Chaudhuri RR, Wang J, Holden MT, Parkhill J, Langford PR, Rycroft AN, Wren BW, Tucker AW, Maskell DJ.

Front Microbiol. 2015 Nov 4;6:1191. doi: 10.3389/fmicb.2015.01191. eCollection 2015.


Chromosomal integration vectors allowing flexible expression of foreign genes in Campylobacter jejuni.

Jervis AJ, Butler JA, Wren BW, Linton D.

BMC Microbiol. 2015 Oct 24;15:230. doi: 10.1186/s12866-015-0559-5.


Draft Genome Sequence of the Enteropathogenic Bacterium Campylobacter jejuni Strain cj255.

Siddiqui FM, Ibrahim M, Noureen N, Noreen Z, Titball RW, Champion OL, Wren BW, Studholme D, Bokhari H.

Genome Announc. 2015 Oct 22;3(5). pii: e01223-15. doi: 10.1128/genomeA.01223-15.

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