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Items: 1 to 20 of 563

1.

Enabling front line-driven perioperative quality improvement through organizational infrastructure built around the Comprehensive Unit Based Safety Program.

Moloo H, Brooke R, Sundaresan S, Skinner B, Berg A, Doering P, Worthington J, Forster A, Schramm D.

Can J Surg. 2016 Dec;59(6):422-424.

PMID:
28234617
2.

Effects of ErbB2 overexpression on the proteome and ErbB ligand-specific phosphosignalling in mammary luminal epithelial cells.

Worthington J, Spain G, Timms JF.

Mol Cell Proteomics. 2017 Feb 7. pii: mcp.M116.061267. doi: 10.1074/mcp.M116.061267. [Epub ahead of print]

3.

Identifying Causal Genes at the Multiple Sclerosis Associated Region 6q23 Using Capture Hi-C.

Martin P, McGovern A, Massey J, Schoenfelder S, Duffus K, Yarwood A, Barton A, Worthington J, Fraser P, Eyre S, Orozco G.

PLoS One. 2016 Nov 18;11(11):e0166923. doi: 10.1371/journal.pone.0166923.

4.

Capture Hi-C identifies a novel causal gene, IL20RA, in the pan-autoimmune genetic susceptibility region 6q23.

McGovern A, Schoenfelder S, Martin P, Massey J, Duffus K, Plant D, Yarwood A, Pratt AG, Anderson AE, Isaacs JD, Diboll J, Thalayasingam N, Ospelt C, Barton A, Worthington J, Fraser P, Eyre S, Orozco G.

Genome Biol. 2016 Nov 1;17(1):212.

5.

Inflammatory cues enhance TGFβ activation by distinct subsets of human intestinal dendritic cells via integrin αvβ8.

Fenton TM, Kelly A, Shuttleworth EE, Smedley C, Atakilit A, Powrie F, Campbell S, Nishimura SL, Sheppard D, Levison S, Worthington JJ, Lehtinen MJ, Travis MA.

Mucosal Immunol. 2016 Oct 26. doi: 10.1038/mi.2016.94. [Epub ahead of print]

PMID:
27782111
6.

Disulfide-activated protein kinase G Iα regulates cardiac diastolic relaxation and fine-tunes the Frank-Starling response.

Scotcher J, Prysyazhna O, Boguslavskyi A, Kistamas K, Hadgraft N, Martin ED, Worthington J, Rudyk O, Rodriguez Cutillas P, Cuello F, Shattock MJ, Marber MS, Conte MR, Greenstein A, Greensmith DJ, Venetucci L, Timms JF, Eaton P.

Nat Commun. 2016 Oct 26;7:13187. doi: 10.1038/ncomms13187.

7.
8.

Escitalopram affects spexin expression in the rat hypothalamus, hippocampus and striatum.

Pałasz A, Suszka-Świtek A, Filipczyk Ł, Bogus K, Rojczyk E, Worthington J, Krzystanek M, Wiaderkiewicz R.

Pharmacol Rep. 2016 Dec;68(6):1326-1331. doi: 10.1016/j.pharep.2016.09.002.

PMID:
27710862
9.

Targeting Hypoxic Prostate Tumors Using the Novel Hypoxia-Activated Prodrug OCT1002 Inhibits Expression of Genes Associated with Malignant Progression.

Nesbitt H, Byrne NM, Williams SN, Ming L, Worthington J, Errington RJ, Patterson LH, Smith PJ, McKeown SR, McKenna DJ.

Clin Cancer Res. 2016 Oct 3. doi: 10.1158/1078-0432.CCR-16-1361. [Epub ahead of print]

PMID:
27697998
10.

A synonymous variant in TREX1 is associated with systemic sclerosis and severe digital ischaemia.

Hughes M, Little J, Herrick AL, Pushpakom S, Byers H, Worthington J, Newman WG.

Scand J Rheumatol. 2017 Jan;46(1):77-78. doi: 10.1080/03009742.2016.1195872. No abstract available.

PMID:
27574969
11.

Extended neuroleptic administration modulates NMDA-R subunit immunoexpression in the rat neocortex and diencephalon.

Krzystanek M, Bogus K, Pałasz A, Wiaderkiewicz A, Filipczyk Ł, Rojczyk E, Worthington J, Wiaderkiewicz R.

Pharmacol Rep. 2016 Oct;68(5):990-5. doi: 10.1016/j.pharep.2016.05.009.

PMID:
27391358
12.

Implementation of a structured hospital-wide morbidity and mortality rounds model.

Kwok ES, Calder LA, Barlow-Krelina E, Mackie C, Seely AJ, Cwinn AA, Worthington JR, Frank JR.

BMJ Qual Saf. 2016 Jun 29. pii: bmjqs-2016-005459. doi: 10.1136/bmjqs-2016-005459. [Epub ahead of print]

PMID:
27358230
13.

Inflammatory cytokines in major depressive disorder: A case-control study.

Cassano P, Bui E, Rogers AH, Walton ZE, Ross R, Zeng M, Nadal-Vicens M, Mischoulon D, Baker AW, Keshaviah A, Worthington J, Hoge EA, Alpert J, Fava M, Wong KK, Simon NM.

Aust N Z J Psychiatry. 2017 Jan;51(1):23-31. doi: 10.1177/0004867416652736.

PMID:
27313138
14.

Women physicians as healthcare leaders: a qualitative study.

Roth VR, Theriault A, Clement C, Worthington J.

J Health Organ Manag. 2016 Jun 20;30(4):648-65. doi: 10.1108/JHOM-09-2014-0164.

PMID:
27296884
15.

Genetic susceptibility to rheumatoid arthritis and its implications for novel drug discovery.

Yarwood A, Eyre S, Worthington J.

Expert Opin Drug Discov. 2016 Aug;11(8):805-13. doi: 10.1080/17460441.2016.1195366.

PMID:
27267163
16.

A combined large-scale meta-analysis identifies COG6 as a novel shared risk locus for rheumatoid arthritis and systemic lupus erythematosus.

Márquez A, Vidal-Bralo L, Rodríguez-Rodríguez L, González-Gay MA, Balsa A, González-Álvaro I, Carreira P, Ortego-Centeno N, Ayala-Gutiérrez MM, García-Hernández FJ, González-Escribano MF, Sabio JM, Tolosa C, Suárez A, González A, Padyukov L, Worthington J, Vyse T, Alarcón-Riquelme ME, Martín J.

Ann Rheum Dis. 2017 Jan;76(1):286-294. doi: 10.1136/annrheumdis-2016-209436.

PMID:
27193031
17.

A method to decipher pleiotropy by detecting underlying heterogeneity driven by hidden subgroups applied to autoimmune and neuropsychiatric diseases.

Han B, Pouget JG, Slowikowski K, Stahl E, Lee CH, Diogo D, Hu X, Park YR, Kim E, Gregersen PK, Dahlqvist SR, Worthington J, Martin J, Eyre S, Klareskog L, Huizinga T, Chen WM, Onengut-Gumuscu S, Rich SS; Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium., Wray NR, Raychaudhuri S.

Nat Genet. 2016 Jul;48(7):803-10. doi: 10.1038/ng.3572.

18.

Tuft Cells: A New Flavor in Innate Epithelial Immunity.

Grencis RK, Worthington JJ.

Trends Parasitol. 2016 Aug;32(8):583-5. doi: 10.1016/j.pt.2016.04.016.

PMID:
27161767
19.

Brief Report: IRF4 Newly Identified as a Common Susceptibility Locus for Systemic Sclerosis and Rheumatoid Arthritis in a Cross-Disease Meta-Analysis of Genome-Wide Association Studies.

López-Isac E, Martín JE, Assassi S, Simeón CP, Carreira P, Ortego-Centeno N, Freire M, Beltrán E, Narváez J, Alegre-Sancho JJ; Spanish Scleroderma Group., Fernández-Gutiérrez B, Balsa A, Ortiz AM, González-Gay MA, Beretta L, Santaniello A, Bellocchi C, Lunardi C, Moroncini G, Gabrielli A, Witte T, Hunzelmann N, Distler JH, Riekemasten G, van der Helm-van Mil AH, de Vries-Bouwstra J, Magro-Checa C, Voskuyl AE, Vonk MC, Molberg Ø, Merriman T, Hesselstrand R, Nordin A, Padyukov L, Herrick A, Eyre S, Koeleman BP, Denton CP, Fonseca C, Radstake TR, Worthington J, Mayes MD, Martín J.

Arthritis Rheumatol. 2016 Sep;68(9):2338-44. doi: 10.1002/art.39730.

PMID:
27111665
20.

Major histocompatibility complex harbors widespread genotypic variability of non-additive risk of rheumatoid arthritis including epistasis.

Wei WH, Bowes J, Plant D, Viatte S, Yarwood A, Massey J, Worthington J, Eyre S.

Sci Rep. 2016 Apr 25;6:25014. doi: 10.1038/srep25014.

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