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Items: 1 to 20 of 39


Atomic resolution experimental phase information reveals extensive disorder and bound 2-methyl-2,4-pentanediol in Ca(2+)-calmodulin.

Lin J, van den Bedem H, Brunger AT, Wilson MA.

Acta Crystallogr D Struct Biol. 2016 Jan;72(Pt 1):83-92. doi: 10.1107/S2059798315021609. Epub 2016 Jan 1.


Regulation of DJ-1 by Glutaredoxin 1 in Vivo: Implications for Parkinson's Disease.

Johnson WM, Golczak M, Choe K, Curran PL, Miller OG, Yao C, Wang W, Lin J, Milkovic NM, Ray A, Ravindranath V, Zhu X, Wilson MA, Wilson-Delfosse AL, Chen SG, Mieyal JJ.

Biochemistry. 2016 Aug 16;55(32):4519-32. doi: 10.1021/acs.biochem.5b01132. Epub 2016 Aug 1.


Some of the most interesting CASP11 targets through the eyes of their authors.

Kryshtafovych A, Moult J, Baslé A, Burgin A, Craig TK, Edwards RA, Fass D, Hartmann MD, Korycinski M, Lewis RJ, Lorimer D, Lupas AN, Newman J, Peat TS, Piepenbrink KH, Prahlad J, van Raaij MJ, Rohwer F, Segall AM, Seguritan V, Sundberg EJ, Singh AK, Wilson MA, Schwede T.

Proteins. 2016 Sep;84 Suppl 1:34-50. doi: 10.1002/prot.24942. Epub 2015 Nov 16.


Transient sampling of aggregation-prone conformations causes pathogenic instability of a parkinsonian mutant of DJ-1 at physiological temperature.

Milkovic NM, Catazaro J, Lin J, Halouska S, Kizziah JL, Basiaga S, Cerny RL, Powers R, Wilson MA.

Protein Sci. 2015 Oct;24(10):1671-85. doi: 10.1002/pro.2762. Epub 2015 Aug 17.


A Chemical Approach for the Detection of Protein Sulfinylation.

Lo Conte M, Lin J, Wilson MA, Carroll KS.

ACS Chem Biol. 2015 Aug 21;10(8):1825-30. doi: 10.1021/acschembio.5b00124. Epub 2015 Jun 17.


Toward resolving the catalytic mechanism of dihydrofolate reductase using neutron and ultrahigh-resolution X-ray crystallography.

Wan Q, Bennett BC, Wilson MA, Kovalevsky A, Langan P, Howell EE, Dealwis C.

Proc Natl Acad Sci U S A. 2014 Dec 23;111(51):18225-30. doi: 10.1073/pnas.1415856111. Epub 2014 Dec 1.


Preliminary joint X-ray and neutron protein crystallographic studies of ecDHFR complexed with folate and NADP+.

Wan Q, Kovalevsky AY, Wilson MA, Bennett BC, Langan P, Dealwis C.

Acta Crystallogr F Struct Biol Commun. 2014 Jun;70(Pt 6):814-8. doi: 10.1107/S2053230X1400942X. Epub 2014 May 25.


Crystal cryocooling distorts conformational heterogeneity in a model Michaelis complex of DHFR.

Keedy DA, van den Bedem H, Sivak DA, Petsko GA, Ringe D, Wilson MA, Fraser JS.

Structure. 2014 Jun 10;22(6):899-910. doi: 10.1016/j.str.2014.04.016. Epub 2014 May 29.


Use of cysteine-reactive cross-linkers to probe conformational flexibility of human DJ-1 demonstrates that Glu18 mutations are dimers.

Prahlad J, Hauser DN, Milkovic NM, Cookson MR, Wilson MA.

J Neurochem. 2014 Sep;130(6):839-53. doi: 10.1111/jnc.12763. Epub 2014 Jun 19.


Metabolic role for yeast DJ-1 superfamily proteins.

Wilson MA.

Proc Natl Acad Sci U S A. 2014 May 13;111(19):6858-9. doi: 10.1073/pnas.1405511111. Epub 2014 Apr 30. No abstract available.


A glutathione-independent glyoxalase of the DJ-1 superfamily plays an important role in managing metabolically generated methylglyoxal in Candida albicans.

Hasim S, Hussin NA, Alomar F, Bidasee KR, Nickerson KW, Wilson MA.

J Biol Chem. 2014 Jan 17;289(3):1662-74. doi: 10.1074/jbc.M113.505784. Epub 2013 Dec 3.


Functional convergence of structurally distinct thioesterases from cyanobacteria and plants involved in phylloquinone biosynthesis.

Furt F, Allen WJ, Widhalm JR, Madzelan P, Rizzo RC, Basset G, Wilson MA.

Acta Crystallogr D Biol Crystallogr. 2013 Oct;69(Pt 10):1876-88. doi: 10.1107/S0907444913015771. Epub 2013 Sep 20.


Visualizing networks of mobility in proteins.

Wilson MA.

Nat Methods. 2013 Sep;10(9):835-7. doi: 10.1038/nmeth.2606. No abstract available.


O-Demethylations catalyzed by Rieske nonheme iron monooxygenases involve the difficult oxidation of a saturated C-H bond.

Jiang W, Wilson MA, Weeks DP.

ACS Chem Biol. 2013 Aug 16;8(8):1687-91. doi: 10.1021/cb400154a. Epub 2013 Jun 10.


Influence of peptide dipoles and hydrogen bonds on reactive cysteine pKa values in fission yeast DJ-1.

Madzelan P, Labunska T, Wilson MA.

FEBS J. 2012 Nov;279(22):4111-20. doi: 10.1111/febs.12004. Epub 2012 Oct 11.


Conservation of oxidative protein stabilization in an insect homologue of parkinsonism-associated protein DJ-1.

Lin J, Prahlad J, Wilson MA.

Biochemistry. 2012 May 8;51(18):3799-807. doi: 10.1021/bi3003296. Epub 2012 Apr 24.


A plant DJ-1 homolog is essential for Arabidopsis thaliana chloroplast development.

Lin J, Nazarenus TJ, Frey JL, Liang X, Wilson MA, Stone JM.

PLoS One. 2011;6(8):e23731. doi: 10.1371/journal.pone.0023731. Epub 2011 Aug 23.


Escherichia coli thioredoxin-like protein YbbN contains an atypical tetratricopeptide repeat motif and is a negative regulator of GroEL.

Lin J, Wilson MA.

J Biol Chem. 2011 Jun 3;286(22):19459-69. doi: 10.1074/jbc.M111.238741. Epub 2011 Apr 15.


The role of cysteine oxidation in DJ-1 function and dysfunction.

Wilson MA.

Antioxid Redox Signal. 2011 Jul 1;15(1):111-22. doi: 10.1089/ars.2010.3481. Epub 2011 Jan 14. Review.


Evolution of new enzymatic function by structural modulation of cysteine reactivity in Pseudomonas fluorescens isocyanide hydratase.

Lakshminarasimhan M, Madzelan P, Nan R, Milkovic NM, Wilson MA.

J Biol Chem. 2010 Sep 17;285(38):29651-61. doi: 10.1074/jbc.M110.147934. Epub 2010 Jul 14.

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