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Items: 1 to 20 of 292

1.

Mucoadhesive amorphous solid dispersions for sustained release of poorly water soluble drugs.

LaFountaine JS, Prasad LK, Miller DA, McGinity JW, Williams RO 3rd.

Eur J Pharm Biopharm. 2017 Jan 11. pii: S0939-6411(16)30384-8. doi: 10.1016/j.ejpb.2016.12.031. [Epub ahead of print]

PMID:
28088635
2.

The Immunogenicity of Thin-Film Freeze-Dried, Aluminum Salt-adjuvanted Vaccine When Exposed to Different Temperatures.

Thakkar SG, Ruwona TB, Williams RO 3rd, Cui Z.

Hum Vaccin Immunother. 2017 Jan 4:0. doi: 10.1080/21645515.2016.1259042. [Epub ahead of print]

PMID:
28051903
3.

Increase in circulating Th17 cells during anti-TNF therapy is associated with ultrasonographic improvement of synovitis in rheumatoid arthritis.

Hull DN, Cooksley H, Chokshi S, Williams RO, Abraham S, Taylor PC.

Arthritis Res Ther. 2016 Dec 23;18(1):303. doi: 10.1186/s13075-016-1197-5.

4.

Influence of process parameters on the preparation of pharmaceutical films by electrostatic powder deposition.

Prasad LK, LaFountaine JS, Keen JM, Williams RO 3rd, McGinity JW.

Int J Pharm. 2016 Dec 30;515(1-2):94-103. doi: 10.1016/j.ijpharm.2016.10.014.

PMID:
27725271
5.

Hot melt extrusion versus spray drying: hot melt extrusion degrades albendazole.

Hengsawas Surasarang S, Keen JM, Huang S, Zhang F, McGinity JW, Williams RO 3rd.

Drug Dev Ind Pharm. 2016 Oct 20:1-15. [Epub ahead of print]

PMID:
27616147
6.

Solubility Advantage (and Disadvantage) of Pharmaceutical Amorphous Solid Dispersions.

Huang S, Mao C, Williams RO 3rd, Yang CY.

J Pharm Sci. 2016 Dec;105(12):3549-3561. doi: 10.1016/j.xphs.2016.08.017.

PMID:
27692620
7.

Impact of the Mass Drug Administration for malaria in response to the Ebola outbreak in Sierra Leone.

Aregawi M, Smith SJ, Sillah-Kanu M, Seppeh J, Kamara AR, Williams RO, Aponte JJ, Bosman A, Alonso P.

Malar J. 2016 Sep 20;15:480. doi: 10.1186/s12936-016-1493-1.

8.

Modified release itraconazole amorphous solid dispersion to treat Aspergillus fumigatus: importance of the animal model selection.

Maincent JP, Najvar LK, Kirkpatrick WR, Huang S, Patterson TF, Wiederhold NP, Peters JI, Williams RO 3rd.

Drug Dev Ind Pharm. 2016 Oct 5:1-11. [Epub ahead of print]

PMID:
27645428
9.

TNF╬▒ in the regulation of Treg and Th17 cells in rheumatoid arthritis and other autoimmune inflammatory diseases.

Bystrom J, Clanchy FI, Taher TE, Mangat P, Jawad AS, Williams RO, Mageed RA.

Cytokine. 2016 Sep 14. pii: S1043-4666(16)30490-2. doi: 10.1016/j.cyto.2016.09.001. [Epub ahead of print]

PMID:
27639923
10.

Abrogation of collagen-induced arthritis by a peptidyl arginine deiminase inhibitor is associated with modulation of T cell-mediated immune responses.

Kawalkowska J, Quirke AM, Ghari F, Davis S, Subramanian V, Thompson PR, Williams RO, Fischer R, La Thangue NB, Venables PJ.

Sci Rep. 2016 May 23;6:26430. doi: 10.1038/srep26430.

11.

Electrostatic powder coating: Principles and pharmaceutical applications.

Prasad LK, McGinity JW, Williams RO 3rd.

Int J Pharm. 2016 May 30;505(1-2):289-302. doi: 10.1016/j.ijpharm.2016.04.016. Review.

PMID:
27085644
12.

Targeted IL-4 therapy synergizes with dexamethasone to induce a state of tolerance by promoting Treg cells and macrophages in mice with arthritis.

Kawalkowska JZ, Hemmerle T, Pretto F, Matasci M, Neri D, Williams RO.

Eur J Immunol. 2016 May;46(5):1246-57. doi: 10.1002/eji.201546221.

PMID:
26919786
13.

Targeting methionyl tRNA synthetase: design, synthesis and antibacterial activity against Clostridium difficile of novel 3-biaryl-N-benzylpropan-1-amine derivatives.

Eissa AG, Blaxland JA, Williams RO, Metwally KA, El-Adl SM, Lashine el-SM, Baillie LW, Simons C.

J Enzyme Inhib Med Chem. 2016 Dec;31(6):1694-7. doi: 10.3109/14756366.2016.1140754.

PMID:
26899668
14.

Use of Polyvinyl Alcohol as a Solubility Enhancing Polymer for Poorly Water-Soluble Drug Delivery (Part 2).

Brough C, Miller DA, Ellenberger D, Lubda D, Williams RO 3rd.

AAPS PharmSciTech. 2016 Feb;17(1):180-90. doi: 10.1208/s12249-016-0490-6.

PMID:
26863889
15.

Enabling thermal processing of ritonavir-polyvinyl alcohol amorphous solid dispersions by KinetiSol® Dispersing.

LaFountaine JS, Jermain SV, Prasad LK, Brough C, Miller DA, Lubda D, McGinity JW, Williams RO 3rd.

Eur J Pharm Biopharm. 2016 Apr;101:72-81. doi: 10.1016/j.ejpb.2016.01.018.

PMID:
26861929
16.

Thermal Processing of PVP- and HPMC-Based Amorphous Solid Dispersions.

LaFountaine JS, Prasad LK, Brough C, Miller DA, McGinity JW, Williams RO 3rd.

AAPS PharmSciTech. 2016 Feb;17(1):120-32. doi: 10.1208/s12249-015-0417-7.

17.

Use of Polyvinyl Alcohol as a Solubility-Enhancing Polymer for Poorly Water Soluble Drug Delivery (Part 1).

Brough C, Miller DA, Keen JM, Kucera SA, Lubda D, Williams RO 3rd.

AAPS PharmSciTech. 2016 Feb;17(1):167-79. doi: 10.1208/s12249-015-0458-y.

18.

Bioavailability enhancement of a BCS IV compound via an amorphous combination product containing ritonavir.

Miller DA, Keen JM, Brough C, Ellenberger DJ, Cisneros M, Williams RO 3rd, McGinity JW.

J Pharm Pharmacol. 2016 May;68(5):678-91. doi: 10.1111/jphp.12478.

PMID:
26454138
19.

Indoleamine 2,3-dioxygenase-1 is protective in atherosclerosis and its metabolites provide new opportunities for drug development.

Cole JE, Astola N, Cribbs AP, Goddard ME, Park I, Green P, Davies AH, Williams RO, Feldmann M, Monaco C.

Proc Natl Acad Sci U S A. 2015 Oct 20;112(42):13033-8. doi: 10.1073/pnas.1517820112.

20.

Effect of hydrophilic additives on the dissolution and pharmacokinetic properties of itraconazole-enteric polymer hot-melt extruded amorphous solid dispersions.

Lang B, Liu S, McGinity JW, Williams RO 3rd.

Drug Dev Ind Pharm. 2016;42(3):429-45. doi: 10.3109/03639045.2015.1075031.

PMID:
26355819
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