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Items: 1 to 20 of 212


Anemia induces gut inflammation and injury in an animal model of preterm infants.

Arthur CM, Nalbant D, Feldman HA, Saeedi BJ, Matthews J, Robinson BS, Kamili NA, Bennett A, Cress GA, Sola-Visner M, Jones RM, Zimmerman MB, Neish AS, Patel RM, Nopoulos P, Georgieff MK, Roback JD, Widness JA, Josephson CD, Stowell SR.

Transfusion. 2019 Apr;59(4):1233-1245. doi: 10.1111/trf.15254. Epub 2019 Mar 21.


A Mechanism-Based Population Pharmacokinetics Model of Erythropoietin in Premature Infants and Healthy Adults Following Multiple Intravenous Doses.

D'Cunha R, Widness JA, Yan X, Schmidt RL, Veng-Pedersen P, An G.

J Clin Pharmacol. 2019 Jun;59(6):835-846. doi: 10.1002/jcph.1368. Epub 2019 Jan 7.


Overlooked Issues on Pharmacokinetics Data Interpretation of Protein Drugs-a Case Example of Erythropoietin.

An G, Schmidt RL, Mock DM, Veng-Pedersen P, Widness JA.

AAPS J. 2018 Nov 26;21(1):6. doi: 10.1208/s12248-018-0269-7. No abstract available.


A Brief History of Milk Hygiene and Its Impact on Infant Mortality from 1875 to 1925 and Implications for Today: A Review.

Currier RW, Widness JA.

J Food Prot. 2018 Oct;81(10):1713-1722. doi: 10.4315/0362-028X.JFP-18-186.


Robust increases in erythropoietin production by the hypoxic fetus is a response to protect the brain and other vital organs.

Teramo KA, Klemetti MM, Widness JA.

Pediatr Res. 2018 Dec;84(6):807-812. doi: 10.1038/s41390-018-0054-4. Epub 2018 Jun 12. Review.


Development, validation, and potential applications of biotinylated red blood cells for posttransfusion kinetics and other physiological studies: evidenced-based analysis and recommendations.

Mock DM, Nalbant D, Kyosseva SV, Schmidt RL, An G, Matthews NI, Vlaar APJ, van Bruggen R, de Korte D, Strauss RG, Cancelas JA, Franco RS, Veng-Pedersen P, Widness JA.

Transfusion. 2018 Aug;58(8):2068-2081. doi: 10.1111/trf.14647. Epub 2018 May 16. Review.


In premature infants there is no decrease in 24-hour posttransfusion allogeneic red blood cell recovery after 42 days of storage.

Nalbant D, Cancelas JA, Mock DM, Kyosseva SV, Schmidt RL, Cress GA, Zimmerman MB, Strauss RG, Widness JA.

Transfusion. 2018 Feb;58(2):352-358. doi: 10.1111/trf.14396. Epub 2017 Nov 29.


Antibodies to biotinylated red blood cells in adults and infants: improved detection, partial characterization, and dependence on red blood cell-biotin dose.

Schmidt RL, Mock DM, Franco RS, Cohen RM, North AK, Cancelas JA, Geisen C, Strauss RG, Vlaar AP, Nalbant D, Widness JA.

Transfusion. 2017 Jun;57(6):1488-1496. doi: 10.1111/trf.14075. Epub 2017 Mar 5.


Population Pharmacokinetics of Darbepoetin in Infants Following Single Intravenous and Subcutaneous Dosing.

An G, Ohls RK, Christensen RD, Widness JA, Mock DM, Veng-Pedersen P.

J Pharm Sci. 2017 Jun;106(6):1644-1649. doi: 10.1016/j.xphs.2017.02.001. Epub 2017 Feb 9.


Estimation of adult and neonatal RBC lifespans in anemic neonates using RBCs labeled at several discrete biotin densities.

Kuruvilla DJ, Widness JA, Nalbant D, Schmidt RL, Mock DM, An G, Veng-Pedersen P.

Pediatr Res. 2017 Jun;81(6):905-910. doi: 10.1038/pr.2017.14. Epub 2017 Jan 18.


Research Opportunities to Improve Neonatal Red Blood Cell Transfusion.

Patel RM, Meyer EK, Widness JA.

Transfus Med Rev. 2016 Oct;30(4):165-73. doi: 10.1016/j.tmrv.2016.06.005. Epub 2016 Jul 4. Review.


A Novel Physiology-Based Mathematical Model to Estimate Red Blood Cell Lifespan in Different Human Age Groups.

An G, Widness JA, Mock DM, Veng-Pedersen P.

AAPS J. 2016 Sep;18(5):1182-91. doi: 10.1208/s12248-016-9923-0. Epub 2016 May 23.


Platelet Transfusion Practices Among Very-Low-Birth-Weight Infants.

Sparger KA, Assmann SF, Granger S, Winston A, Christensen RD, Widness JA, Josephson C, Stowell SR, Saxonhouse M, Sola-Visner M.

JAMA Pediatr. 2016 Jul 1;170(7):687-94. doi: 10.1001/jamapediatrics.2016.0507.


Clearance of stored red blood cells is not increased compared with fresh red blood cells in a human endotoxemia model.

Peters AL, Beuger B, Mock DM, Widness JA, de Korte D, Juffermans NP, Vlaar AP, van Bruggen R.

Transfusion. 2016 Jun;56(6):1362-9. doi: 10.1111/trf.13595. Epub 2016 Apr 4.


Models for the red blood cell lifespan.

Shrestha RP, Horowitz J, Hollot CV, Germain MJ, Widness JA, Mock DM, Veng-Pedersen P, Chait Y.

J Pharmacokinet Pharmacodyn. 2016 Jun;43(3):259-74. doi: 10.1007/s10928-016-9470-4. Epub 2016 Apr 2.


Iron is prioritized to red blood cells over the brain in phlebotomized anemic newborn lambs.

Zamora TG, Guiang SF 3rd, Widness JA, Georgieff MK.

Pediatr Res. 2016 Jun;79(6):922-8. doi: 10.1038/pr.2016.20. Epub 2016 Feb 11.


Predictive factors and practice trends in red blood cell transfusions for very-low-birth-weight infants.

Ekhaguere OA, Morriss FH Jr, Bell EF, Prakash N, Widness JA.

Pediatr Res. 2016 May;79(5):736-41. doi: 10.1038/pr.2016.4. Epub 2016 Jan 12.


A Mass Balance-Based Semiparametric Approach to Evaluate Neonatal Erythropoiesis.

Kuruvilla DJ, Widness JA, Nalbant D, Schmidt RL, Mock DM, Veng-Pedersen P.

AAPS J. 2016 Jan;18(1):187-95. doi: 10.1208/s12248-015-9831-8. Epub 2015 Oct 26.


Autologous Infant and Allogeneic Adult Red Cells Demonstrate Similar Concurrent Post-Transfusion Survival in Very Low Birth Weight Neonates.

Widness JA, Kuruvilla DJ, Mock DM, Matthews NI, Nalbant D, Cress GA, Schmidt RL, Strauss RG, Zimmerman MB, Veng-Pedersen P.

J Pediatr. 2015 Nov;167(5):1001-6. doi: 10.1016/j.jpeds.2015.08.028. Epub 2015 Sep 9.


A Method to Evaluate Fetal Erythropoiesis from Postnatal Survival of Fetal RBCs.

Kuruvilla DJ, Widness JA, Nalbant D, Schmidt RL, Mock DM, Veng-Pedersen P.

AAPS J. 2015 Sep;17(5):1246-54. doi: 10.1208/s12248-015-9784-y. Epub 2015 May 28.

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