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Items: 1 to 20 of 161


Psychosocial morbidity in women with abnormal cervical cytology managed by cytological surveillance or initial colposcopy: longitudinal analysis from the TOMBOLA randomised trial.

Fielding S, Rothnie K, Gray NM, Little J, Cruickshank ME, Neal K, Walker LG, Whynes D, Cotton SC, Sharp L; In association with the TOMBOLA group.

Psychooncology. 2017 Apr;26(4):476-483. doi: 10.1002/pon.4163. Epub 2016 Jun 14.


The UK Lung Cancer Screening Trial: a pilot randomised controlled trial of low-dose computed tomography screening for the early detection of lung cancer.

Field JK, Duffy SW, Baldwin DR, Brain KE, Devaraj A, Eisen T, Green BA, Holemans JA, Kavanagh T, Kerr KM, Ledson M, Lifford KJ, McRonald FE, Nair A, Page RD, Parmar MK, Rintoul RC, Screaton N, Wald NJ, Weller D, Whynes DK, Williamson PR, Yadegarfar G, Hansell DM.

Health Technol Assess. 2016 May;20(40):1-146. doi: 10.3310/hta20400.


Intravenous tranexamic acid for hyperacute primary intracerebral hemorrhage: Protocol for a randomized, placebo-controlled trial.

Sprigg N, Robson K, Bath P, Dineen R, Roberts I, Robinson T, Roffe C, Werring D, Al-Shahi Salman R, Pocock S, Duley L, England T, Whynes D, Ciccone A, Laska AC, Christensen H, Ozturk S, Collins R, Bereczki D, Egea-Guerrero JJ, Law ZK, Czlonkowska A, Seiffge D, Beredzie M; TICH-2 Investigators.

Int J Stroke. 2016 Aug;11(6):683-94. doi: 10.1177/1747493016641960. Epub 2016 Apr 5.


UK Lung Cancer RCT Pilot Screening Trial: baseline findings from the screening arm provide evidence for the potential implementation of lung cancer screening.

Field JK, Duffy SW, Baldwin DR, Whynes DK, Devaraj A, Brain KE, Eisen T, Gosney J, Green BA, Holemans JA, Kavanagh T, Kerr KM, Ledson M, Lifford KJ, McRonald FE, Nair A, Page RD, Parmar MK, Rassl DM, Rintoul RC, Screaton NJ, Wald NJ, Weller D, Williamson PR, Yadegarfar G, Hansell DM.

Thorax. 2016 Feb;71(2):161-70. doi: 10.1136/thoraxjnl-2015-207140. Epub 2015 Dec 8.


Impact of post-colposcopy management on women's long-term worries: results from the UK population-based TOMBOLA trial.

Sharp L, Cotton S, Cruickshank M, Gray N, Smart L, Whynes D, Little J; TOMBOLA Group.

J Fam Plann Reprod Health Care. 2016 Jan;42(1):43-51. doi: 10.1136/jfprhc-2015-101170. Epub 2015 Sep 16.


Cost-effectiveness of volar locking plate versus percutaneous fixation for distal radial fractures: Economic evaluation alongside a randomised clinical trial.

Karantana A, Scammell BE, Davis TR, Whynes DK.

Bone Joint J. 2015 Sep;97-B(9):1264-70. doi: 10.1302/0301-620X.97B9.35560.


Long-Term Worries after Colposcopy: Which Women Are at Increased Risk?

Sharp L, Cotton SC, Cruickshank ME, Gray NM, Neal K, Rothnie K, Thornton AJ, Walker LG, Little J; TOMBOLA Group.

Womens Health Issues. 2015 Sep-Oct;25(5):517-27. doi: 10.1016/j.whi.2015.04.002. Epub 2015 Jun 4.


Blinded randomised controlled trial of low-dose Adjuvant Steroids in Adults admitted to hospital with Pandemic influenza (ASAP): a trial 'in hibernation', ready for rapid activation.

Lim WS, Brittain C, Duley L, Edwards S, Gordon S, Montgomery A, Nguyen-Van-Tam J, Read R, Whitham D, Whynes D, Woodhead M, Wootton D.

Health Technol Assess. 2015 Feb;19(16):1-78, vii-viii. doi: 10.3310/hta19160.


Cost comparison of re-usable and single-use fibrescopes in a large English teaching hospital.

McCahon RA, Whynes DK.

Anaesthesia. 2015 Jun;70(6):699-706. doi: 10.1111/anae.13011. Epub 2015 Jan 31.


Efficacy of nitric oxide, with or without continuing antihypertensive treatment, for management of high blood pressure in acute stroke (ENOS): a partial-factorial randomised controlled trial.

ENOS Trial Investigators, Bath PM, Woodhouse L, Scutt P, Krishnan K, Wardlaw JM, Bereczki D, Sprigg N, Berge E, Beridze M, Caso V, Chen C, Christensen H, Collins R, El Etribi A, Laska AC, Lees KR, Ozturk S, Phillips S, Pocock S, de Silva HA, Szatmari S, Utton S.

Lancet. 2015 Feb 14;385(9968):617-28. doi: 10.1016/S0140-6736(14)61121-1. Epub 2014 Oct 21. Erratum in: Lancet. 2015 Feb 14;385(9968):606.


A normal colposcopy examination fails to provide psychological reassurance for women who have had low-grade abnormal cervical cytology.

Cotton SC, Sharp L, Little J, Gray NM, Walker LG, Whynes DK, Cruickshank ME; TOMBOLA Group.

Cytopathology. 2015 Jun;26(3):178-87. doi: 10.1111/cyt.12173. Epub 2014 Aug 6.


The UK Lung Screen (UKLS): demographic profile of first 88,897 approaches provides recommendations for population screening.

McRonald FE, Yadegarfar G, Baldwin DR, Devaraj A, Brain KE, Eisen T, Holemans JA, Ledson M, Screaton N, Rintoul RC, Hands CJ, Lifford K, Whynes D, Kerr KM, Page R, Parmar M, Wald N, Weller D, Williamson PR, Myles J, Hansell DM, Duffy SW, Field JK.

Cancer Prev Res (Phila). 2014 Mar;7(3):362-71. doi: 10.1158/1940-6207.CAPR-13-0206. Epub 2014 Jan 17.


Effect of 3 to 5 years of scheduled CEA and CT follow-up to detect recurrence of colorectal cancer: the FACS randomized clinical trial.

Primrose JN, Perera R, Gray A, Rose P, Fuller A, Corkhill A, George S, Mant D; FACS Trial Investigators.

JAMA. 2014 Jan 15;311(3):263-70. doi: 10.1001/jama.2013.285718.


The unintended consequences of cervical screening: distress in women undergoing cytologic surveillance.

Sharp L, Cotton S, Cruickshank M, Gray NM, Harrild K, Smart L, Walker LG, Little J; TOMBOLA Group.

J Low Genit Tract Dis. 2014 Apr;18(2):142-50. doi: 10.1097/LGT.0b013e31829c97d8.


Very low quality of life after acute stroke: data from the Efficacy of Nitric Oxide in Stroke trial.

Sprigg N, Selby J, Fox L, Berge E, Whynes D, Bath PM; Efficacy of Nitric Oxide in Stroke Investigators.

Stroke. 2013 Dec;44(12):3458-62. doi: 10.1161/STROKEAHA.113.002201. Epub 2013 Oct 22.


Does the correspondence between EQ-5D health state description and VAS score vary by medical condition?

Whynes DK.

Health Qual Life Outcomes. 2013 Sep 13;11:155. doi: 10.1186/1477-7525-11-155.


European randomized lung cancer screening trials: Post NLST.

Field JK, van Klaveren R, Pedersen JH, Pastorino U, Paci E, Becker N, Infante M, Oudkerk M, de Koning HJ; European Randomized Screening Trial Group.

J Surg Oncol. 2013 Oct;108(5):280-6. doi: 10.1002/jso.23383. Epub 2013 Jul 25.


Evaluation of mammographic surveillance services in women aged 40-49 years with a moderate family history of breast cancer: a single-arm cohort study.

Duffy SW, Mackay J, Thomas S, Anderson E, Chen TH, Ellis I, Evans G, Fielder H, Fox R, Gui G, Macmillan D, Moss S, Rogers C, Sibbering M, Wallis M, Warren R, Watson E, Whynes D, Allgood P, Caunt J.

Health Technol Assess. 2013 Mar;17(11):vii-xiv, 1-95. doi: 10.3310/hta17110.


Impact of alternative management policies on health-related quality of life in women with low-grade abnormal cervical cytology referred for colposcopy.

Whynes DK, Sharp L, Cotton SC, Cruickshank M, Gray NM, Little J, Waugh N.

Eur J Obstet Gynecol Reprod Biol. 2013 Jul;169(1):88-92. doi: 10.1016/j.ejogrb.2013.02.006. Epub 2013 Mar 5.


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