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Items: 1 to 20 of 79

1.

Hepatic Dysfunction Caused by Consumption of a High-Fat Diet.

Soltis AR, Kennedy NJ, Xin X, Zhou F, Ficarro SB, Yap YS, Matthews BJ, Lauffenburger DA, White FM, Marto JA, Davis RJ, Fraenkel E.

Cell Rep. 2017 Dec 12;21(11):3317-3328. doi: 10.1016/j.celrep.2017.11.059.

2.

Camptothecin resistance is determined by the regulation of topoisomerase I degradation mediated by ubiquitin proteasome pathway.

Ando K, Shah AK, Sachdev V, Kleinstiver BP, Taylor-Parker J, Welch MM, Hu Y, Salgia R, White FM, Parvin JD, Ozonoff A, Rameh LE, Joung JK, Bharti AK.

Oncotarget. 2017 Jul 4;8(27):43733-43751. doi: 10.18632/oncotarget.16376.

3.

Revealing disease-associated pathways by network integration of untargeted metabolomics.

Pirhaji L, Milani P, Leidl M, Curran T, Avila-Pacheco J, Clish CB, White FM, Saghatelian A, Fraenkel E.

Nat Methods. 2016 Sep;13(9):770-6. doi: 10.1038/nmeth.3940. Epub 2016 Aug 1.

4.

Network Modeling Identifies Patient-specific Pathways in Glioblastoma.

Tuncbag N, Milani P, Pokorny JL, Johnson H, Sio TT, Dalin S, Iyekegbe DO, White FM, Sarkaria JN, Fraenkel E.

Sci Rep. 2016 Jun 29;6:28668. doi: 10.1038/srep28668.

5.

Quantitative Phosphoproteomics Reveals Wee1 Kinase as a Therapeutic Target in a Model of Proneural Glioblastoma.

Lescarbeau RS, Lei L, Bakken KK, Sims PA, Sarkaria JN, Canoll P, White FM.

Mol Cancer Ther. 2016 Jun;15(6):1332-43. doi: 10.1158/1535-7163.MCT-15-0692. Epub 2016 May 17.

6.

Time-resolved multimodal analysis of Src Homology 2 (SH2) domain binding in signaling by receptor tyrosine kinases.

Jadwin JA, Oh D, Curran TG, Ogiue-Ikeda M, Jia L, White FM, Machida K, Yu J, Mayer BJ.

Elife. 2016 Apr 12;5:e11835. doi: 10.7554/eLife.11835.

7.

A Thermodynamic-Based Interpretation of Protein Expression Heterogeneity in Different Glioblastoma Multiforme Tumors Identifies Tumor-Specific Unbalanced Processes.

Kravchenko-Balasha N, Johnson H, White FM, Heath JR, Levine RD.

J Phys Chem B. 2016 Jul 7;120(26):5990-7. doi: 10.1021/acs.jpcb.6b01692. Epub 2016 Apr 12.

8.

Early signaling dynamics of the epidermal growth factor receptor.

Reddy RJ, Gajadhar AS, Swenson EJ, Rothenberg DA, Curran TG, White FM.

Proc Natl Acad Sci U S A. 2016 Mar 15;113(11):3114-9. doi: 10.1073/pnas.1521288113. Epub 2016 Feb 29.

9.

CNS Anticancer Drug Discovery and Development Conference White Paper.

Levin VA, Tonge PJ, Gallo JM, Birtwistle MR, Dar AC, Iavarone A, Paddison PJ, Heffron TP, Elmquist WF, Lachowicz JE, Johnson TW, White FM, Sul J, Smith QR, Shen W, Sarkaria JN, Samala R, Wen PY, Berry DA, Petter RC.

Neuro Oncol. 2015 Nov;17 Suppl 6:vi1-26. doi: 10.1093/neuonc/nov169.

10.

PTP1B-dependent regulation of receptor tyrosine kinase signaling by the actin-binding protein Mena.

Hughes SK, Oudin MJ, Tadros J, Neil J, Del Rosario A, Joughin BA, Ritsma L, Wyckoff J, Vasile E, Eddy R, Philippar U, Lussiez A, Condeelis JS, van Rheenen J, White F, Lauffenburger DA, Gertler FB.

Mol Biol Cell. 2015 Nov 1;26(21):3867-78. doi: 10.1091/mbc.E15-06-0442. Epub 2015 Sep 2.

11.

Minor Changes in Expression of the Mismatch Repair Protein MSH2 Exert a Major Impact on Glioblastoma Response to Temozolomide.

McFaline-Figueroa JL, Braun CJ, Stanciu M, Nagel ZD, Mazzucato P, Sangaraju D, Cerniauskas E, Barford K, Vargas A, Chen Y, Tretyakova N, Lees JA, Hemann MT, White FM, Samson LD.

Cancer Res. 2015 Aug 1;75(15):3127-38. doi: 10.1158/0008-5472.CAN-14-3616. Epub 2015 May 29.

12.

Quantitative Profiling of Lysine Acetylation Reveals Dynamic Crosstalk between Receptor Tyrosine Kinases and Lysine Acetylation.

Bryson BD, White FM.

PLoS One. 2015 May 15;10(5):e0126242. doi: 10.1371/journal.pone.0126242. eCollection 2015.

13.

Phosphotyrosine signaling analysis in human tumors is confounded by systemic ischemia-driven artifacts and intra-specimen heterogeneity.

Gajadhar AS, Johnson H, Slebos RJ, Shaddox K, Wiles K, Washington MK, Herline AJ, Levine DA, Liebler DC, White FM; Clinical Proteomic Tumor Analysis Consortium.

Cancer Res. 2015 Apr 1;75(7):1495-503. doi: 10.1158/0008-5472.CAN-14-2309. Epub 2015 Feb 10.

14.

Engineered bromodomains to explore the acetylproteome.

Bryson BD, Del Rosario AM, Gootenberg JS, Yaffe MB, White FM.

Proteomics. 2015 May;15(9):1470-5. doi: 10.1002/pmic.201400401. Epub 2015 Mar 5.

15.

MARQUIS: a multiplex method for absolute quantification of peptides and posttranslational modifications.

Curran TG, Zhang Y, Ma DJ, Sarkaria JN, White FM.

Nat Commun. 2015 Jan 12;6:5924. doi: 10.1038/ncomms6924.

16.

ATRX directs binding of PRC2 to Xist RNA and Polycomb targets.

Sarma K, Cifuentes-Rojas C, Ergun A, Del Rosario A, Jeon Y, White F, Sadreyev R, Lee JT.

Cell. 2014 Nov 6;159(4):869-83. doi: 10.1016/j.cell.2014.10.019. Erratum in: Cell. 2015 Jan 29;160(3):568-9. Cell. 2014 Nov 20;159(5):1228.

17.

SirT1 is required in the male germ cell for differentiation and fecundity in mice.

Bell EL, Nagamori I, Williams EO, Del Rosario AM, Bryson BD, Watson N, White FM, Sassone-Corsi P, Guarente L.

Development. 2014 Sep;141(18):3495-504. doi: 10.1242/dev.110627. Epub 2014 Aug 19.

18.

Quantitative analysis of signaling networks across differentially embedded tumors highlights interpatient heterogeneity in human glioblastoma.

Johnson H, White FM.

J Proteome Res. 2014 Nov 7;13(11):4581-93. doi: 10.1021/pr500418w. Epub 2014 Jun 24.

19.

Ischemia in tumors induces early and sustained phosphorylation changes in stress kinase pathways but does not affect global protein levels.

Mertins P, Yang F, Liu T, Mani DR, Petyuk VA, Gillette MA, Clauser KR, Qiao JW, Gritsenko MA, Moore RJ, Levine DA, Townsend R, Erdmann-Gilmore P, Snider JE, Davies SR, Ruggles KV, Fenyo D, Kitchens RT, Li S, Olvera N, Dao F, Rodriguez H, Chan DW, Liebler D, White F, Rodland KD, Mills GB, Smith RD, Paulovich AG, Ellis M, Carr SA.

Mol Cell Proteomics. 2014 Jul;13(7):1690-704. doi: 10.1074/mcp.M113.036392. Epub 2014 Apr 9.

20.

System level dynamics of post-translational modifications.

Gajadhar AS, White FM.

Curr Opin Biotechnol. 2014 Aug;28:83-7. doi: 10.1016/j.copbio.2013.12.009. Epub 2014 Jan 15. Review.

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