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Items: 18

1.

CCI-007, a novel small molecule with cytotoxic activity against infant leukemia with MLL rearrangements.

Somers K, Chudakova DA, Middlemiss SM, Wen VW, Clifton M, Kwek A, Liu B, Mayoh C, Bongers A, Karsa M, Pan S, Cruikshank S, Scandlyn M, Hoang W, Imamura T, Kees UR, Gudkov AV, Chernova OB, Haber M, Norris MD, Henderson MJ.

Oncotarget. 2016 Jul 19;7(29):46067-46087. doi: 10.18632/oncotarget.10022.

2.

Intensive versus conventional glucose control in critically ill patients with traumatic brain injury: long-term follow-up of a subgroup of patients from the NICE-SUGAR study.

NICE-SUGAR Study Investigators for the Australian and New Zealand Intensive Care Society Clinical Trials Group and the Canadian Critical Care Trials Group, Finfer S, Chittock D, Li Y, Foster D, Dhingra V, Bellomo R, Cook D, Dodek P, Hebert P, Henderson W, Heyland D, Higgins A, McArthur C, Mitchell I, Myburgh J, Robinson B, Ronco J.

Intensive Care Med. 2015 Jun;41(6):1037-47. doi: 10.1007/s00134-015-3757-6. Epub 2015 Jun 19.

PMID:
26088909
3.

Prevalence, risk factors, and outcomes of delirium in mechanically ventilated adults.

Mehta S, Cook D, Devlin JW, Skrobik Y, Meade M, Fergusson D, Herridge M, Steinberg M, Granton J, Ferguson N, Tanios M, Dodek P, Fowler R, Burns K, Jacka M, Olafson K, Mallick R, Reynolds S, Keenan S, Burry L; SLEAP Investigators; Canadian Critical Care Trials Group.

Crit Care Med. 2015 Mar;43(3):557-66. doi: 10.1097/CCM.0000000000000727.

PMID:
25493968
4.

Hepatocyte produced matrix metalloproteinases are regulated by CD147 in liver fibrogenesis.

Calabro SR, Maczurek AE, Morgan AJ, Tu T, Wen VW, Yee C, Mridha A, Lee M, d'Avigdor W, Locarnini SA, McCaughan GW, Warner FJ, McLennan SV, Shackel NA.

PLoS One. 2014 Jul 30;9(7):e90571. doi: 10.1371/journal.pone.0090571. eCollection 2014.

5.

Case management in an acute-care hospital: collaborating for quality, cost-effective patient care.

Grootveld K, Wen V, Bather M, Park J.

Healthc Q. 2014;17(1):60-5.

PMID:
24844723
6.

Heparin-induced thrombocytopenia in the critically ill: interpreting the 4Ts test in a randomized trial.

Crowther M, Cook D, Guyatt G, Zytaruk N, McDonald E, Williamson D, Albert M, Dodek P, Finfer S, Vallance S, Heels-Ansdell D, McIntyre L, Mehta S, Lamontagne F, Muscedere J, Jacka M, Lesur O, Kutsiogiannis J, Friedrich J, Klinger JR, Qushmaq I, Burry L, Khwaja K, Sheppard JA, Warkentin TE; PROTECT collaborators; Canadian Critical Care Trials Group; Australian and New Zealand Intensive Care Society Clinical Trials Group.

J Crit Care. 2014 Jun;29(3):470.e7-15. doi: 10.1016/j.jcrc.2014.02.004. Epub 2014 Feb 14.

PMID:
24726205
7.

Modeling human endothelial cell transformation in vascular neoplasias.

Wen VW, MacKenzie KL.

Dis Model Mech. 2013 Sep;6(5):1066-79. doi: 10.1242/dmm.012674. Review.

8.

Cyclin E facilitates dysplastic hepatocytes to bypass G1/S checkpoint in hepatocarcinogenesis.

Pok S, Wen V, Shackel N, Alsop A, Pyakurel P, Fahrer A, Farrell GC, Teoh NC.

J Gastroenterol Hepatol. 2013 Sep;28(9):1545-54. doi: 10.1111/jgh.12216.

PMID:
23574010
9.

Co-enrollment of critically ill patients into multiple studies: patterns, predictors and consequences.

Cook D, McDonald E, Smith O, Zytaruk N, Heels-Ansdell D, Watpool I, McArdle T, Matte A, Clarke F, Vallance S, Finfer S, Galt P, Crozier T, Fowler R, Arabi Y, Woolfe C, Orford N, Hall R, Adhikari NK, Ferland MC, Marshall J, Meade M; PROTECT Research Coordinators; PROTECT Investigators; Canadian Critical Care Trials Group; Australian and New Zealand Intensive Care Society Clinical Trials Group.

Crit Care. 2013 Jan 8;17(1):R1. doi: 10.1186/cc11917.

10.

Rates and determinants of informed consent: a case study of an international thromboprophylaxis trial.

Smith OM, McDonald E, Zytaruk N, Foster D, Matte A, Clarke F, Meade L, O'Callaghan N, Vallance S, Galt P, Rajbhandari D, Rocha M, Mehta S, Ferguson ND, Hall R, Fowler R, Burns K, Qushmaq I, Ostermann M, Heels-Ansdell D, Cook D; PROTECT Research Coordinators; PROTECT Investigators; Canadian Critical Care Trials Group; Australian, New Zealand Intensive Care Society Clinical Trials Group.

J Crit Care. 2013 Feb;28(1):28-39. doi: 10.1016/j.jcrc.2012.08.005. Epub 2012 Oct 22.

PMID:
23089679
11.

Endothelial cell dysfunction and cytoskeletal changes associated with repression of p16(INK4a) during immortalization.

Kan CY, Wen VW, Pasquier E, Jankowski K, Chang M, Richards LA, Kavallaris M, MacKenzie KL.

Oncogene. 2012 Nov 15;31(46):4815-27. doi: 10.1038/onc.2011.645. Epub 2012 Feb 6.

12.

Single-incision laparoscopic appendectomy: prospective case series at a single centre in Singapore.

Goel R, Buhari SA, Foo J, Chung LK, Wen VL, Agarwal A, Lomanto D.

Surg Laparosc Endosc Percutan Tech. 2011 Oct;21(5):318-21. doi: 10.1097/SLE.0b013e3182311bd9.

PMID:
22002266
13.

Single port laparoscopic liver resection for hepatocellular carcinoma: a preliminary report.

Chang SK, Mayasari M, Ganpathi IS, Wen VL, Madhavan K.

Int J Hepatol. 2011;2011:579203. doi: 10.4061/2011/579203. Epub 2011 May 26.

14.

Mild hyperoxia limits hTR levels, telomerase activity, and telomere length maintenance in hTERT-transduced bone marrow endothelial cells.

Napier CE, Veas LA, Kan CY, Taylor LM, Yuan J, Wen VW, James A, O'Brien TA, Lock RB, MacKenzie KL.

Biochim Biophys Acta. 2010 Oct;1803(10):1142-53. doi: 10.1016/j.bbamcr.2010.06.010. Epub 2010 Jul 7.

15.

Targeting telomerase in hematologic malignancy.

Maritz MF, Napier CE, Wen VW, MacKenzie KL.

Future Oncol. 2010 May;6(5):769-89. doi: 10.2217/fon.10.42. Review.

PMID:
20465390
16.

Intensive versus conventional glucose control in critically ill patients.

NICE-SUGAR Study Investigators, Finfer S, Chittock DR, Su SY, Blair D, Foster D, Dhingra V, Bellomo R, Cook D, Dodek P, Henderson WR, H├ębert PC, Heritier S, Heyland DK, McArthur C, McDonald E, Mitchell I, Myburgh JA, Norton R, Potter J, Robinson BG, Ronco JJ.

N Engl J Med. 2009 Mar 26;360(13):1283-97. doi: 10.1056/NEJMoa0810625. Epub 2009 Mar 24.

17.

Telomere-driven karyotypic complexity concurs with p16INK4a inactivation in TP53-competent immortal endothelial cells.

Wen VW, Wu K, Baksh S, Hinshelwood RA, Lock RB, Clark SJ, Moore MA, Mackenzie KL.

Cancer Res. 2006 Nov 15;66(22):10691-700.

18.

Over-expression of p53 mutants in LNCaP cells alters tumor growth and angiogenesis in vivo.

Perryman LA, Blair JM, Kingsley EA, Szymanska B, Ow KT, Wen VW, MacKenzie KL, Vermeulen PB, Jackson P, Russell PJ.

Biochem Biophys Res Commun. 2006 Jul 7;345(3):1207-14. Epub 2006 May 11.

PMID:
16723121

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