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Items: 1 to 20 of 161


Activation of ERK and NF-κB during HARE-Mediated Heparin Uptake Require Only One of the Four Endocytic Motifs.

Pandey MS, Miller CM, Harris EN, Weigel PH.

PLoS One. 2016 Apr 21;11(4):e0154124. doi: 10.1371/journal.pone.0154124.


Advances in Hyaluronan Biology: Signaling, Regulation, and Disease Mechanisms.

Simpson MA, de la Motte C, Sherman LS, Weigel PH.

Int J Cell Biol. 2015;2015:690572. doi: 10.1155/2015/690572. No abstract available.


HARE-Mediated Endocytosis of Hyaluronan and Heparin Is Targeted by Different Subsets of Three Endocytic Motifs.

Pandey MS, Harris EN, Weigel PH.

Int J Cell Biol. 2015;2015:524707. doi: 10.1155/2015/524707.


Hyaluronan synthase assembles chitin oligomers with -GlcNAc(α1→)UDP at the reducing end.

Weigel PH, West CM, Zhao P, Wells L, Baggenstoss BA, Washburn JL.

Glycobiology. 2015 Jun;25(6):632-43. doi: 10.1093/glycob/cwv006.


Methods for measuring Class I membrane-bound hyaluronan synthase activity.

Weigel PH, Padgett-McCue AJ, Baggenstoss BA.

Methods Mol Biol. 2013;1022:229-47. doi: 10.1007/978-1-62703-465-4_18.


The hyaluronan receptor for endocytosis (HARE) activates NF-κB-mediated gene expression in response to 40-400-kDa, but not smaller or larger, hyaluronans.

Pandey MS, Baggenstoss BA, Washburn J, Harris EN, Weigel PH.

J Biol Chem. 2013 May 17;288(20):14068-79. doi: 10.1074/jbc.M112.442889.


Digestion products of the PH20 hyaluronidase inhibit remyelination.

Preston M, Gong X, Su W, Matsumoto SG, Banine F, Winkler C, Foster S, Xing R, Struve J, Dean J, Baggenstoss B, Weigel PH, Montine TJ, Back SA, Sherman LS.

Ann Neurol. 2013 Feb;73(2):266-80. doi: 10.1002/ana.23788.


Tumor necrosis factor-stimulated gene-6 (TSG-6) amplifies hyaluronan synthesis by airway smooth muscle cells.

Lauer ME, Cheng G, Swaidani S, Aronica MA, Weigel PH, Hascall VC.

J Biol Chem. 2013 Jan 4;288(1):423-31. doi: 10.1074/jbc.M112.389882.


Hyaluronan turnover and hypoxic brown adipocytic differentiation are co-localized with ossification in calcified human aortic valves.

Stephens EH, Saltarrelli JG Jr, Balaoing LR, Baggett LS, Nandi I, Anderson KM, Morrisett JD, Reardon MJ, Simpson MA, Weigel PH, Olmsted-Davis EA, Davis AR, Grande-Allen KJ.

Pathol Res Pract. 2012 Nov 15;208(11):642-50. doi: 10.1016/j.prp.2012.08.001.


Hyaluronan synthase mediates dye translocation across liposomal membranes.

Medina AP, Lin J, Weigel PH.

BMC Biochem. 2012 Jan 25;13:2. doi: 10.1186/1471-2091-13-2.


Systemic blockade of the hyaluronan receptor for endocytosis prevents lymph node metastasis of prostate cancer.

Simpson MA, Weigel JA, Weigel PH.

Int J Cancer. 2012 Sep 1;131(5):E836-40. doi: 10.1002/ijc.27427.


Clustered Conserved Cysteines in Hyaluronan Synthase Mediate Cooperative Activation by Mg2+ Ions and Severe Inhibitory Effects of Divalent Cations.

Tlapak-Simmons VL, Medina AP, Baggenstoss BA, Nguyen L, Baron CA, Weigel PH.

J Glycomics Lipidomics. 2011 Nov 15;Suppl 1:001.


Increased hyaluronan synthase-2 mRNA expression and hyaluronan accumulation with choroidal thickening: response during recovery from induced myopia.

Rada JA, Wiechmann AF, Hollaway LR, Baggenstoss BA, Weigel PH.

Invest Ophthalmol Vis Sci. 2010 Dec;51(12):6172-9. doi: 10.1167/iovs.10-5522.


N-Glycans on the link domain of human HARE/Stabilin-2 are needed for hyaluronan binding to purified ecto-domain, but not for cellular endocytosis of hyaluronan.

Harris EN, Parry S, Sutton-Smith M, Pandey MS, Panico M, Morris HR, Haslam SM, Dell A, Weigel PH.

Glycobiology. 2010 Aug;20(8):991-1001. doi: 10.1093/glycob/cwq057.


Rat and human HARE/stabilin-2 are clearance receptors for high- and low-molecular-weight heparins.

Harris EN, Baggenstoss BA, Weigel PH.

Am J Physiol Gastrointest Liver Physiol. 2009 Jun;296(6):G1191-9. doi: 10.1152/ajpgi.90717.2008.

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