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Regulation of normal B-cell differentiation and malignant B-cell survival by OCT2.

Hodson DJ, Shaffer AL, Xiao W, Wright GW, Schmitz R, Phelan JD, Yang Y, Webster DE, Rui L, Kohlhammer H, Nakagawa M, Waldmann TA, Staudt LM.

Proc Natl Acad Sci U S A. 2016 Apr 5;113(14):E2039-46. doi: 10.1073/pnas.1600557113.


The noncoding RNAs SNORD50A and SNORD50B bind K-Ras and are recurrently deleted in human cancer.

Siprashvili Z, Webster DE, Johnston D, Shenoy RM, Ungewickell AJ, Bhaduri A, Flockhart R, Zarnegar BJ, Che Y, Meschi F, Puglisi JD, Khavari PA.

Nat Genet. 2016 Jan;48(1):53-8. doi: 10.1038/ng.3452.


A LncRNA-MAF:MAFB transcription factor network regulates epidermal differentiation.

Lopez-Pajares V, Qu K, Zhang J, Webster DE, Barajas BC, Siprashvili Z, Zarnegar BJ, Boxer LD, Rios EJ, Tao S, Kretz M, Khavari PA.

Dev Cell. 2015 Mar 23;32(6):693-706. doi: 10.1016/j.devcel.2015.01.028.


Dicer-microRNA-Myc circuit promotes transcription of hundreds of long noncoding RNAs.

Zheng GX, Do BT, Webster DE, Khavari PA, Chang HY.

Nat Struct Mol Biol. 2014 Jul;21(7):585-90. doi: 10.1038/nsmb.2842.


Enhancer-targeted genome editing selectively blocks innate resistance to oncokinase inhibition.

Webster DE, Barajas B, Bussat RT, Yan KJ, Neela PH, Flockhart RJ, Kovalski J, Zehnder A, Khavari PA.

Genome Res. 2014 May;24(5):751-60. doi: 10.1101/gr.166231.113.


Control of somatic tissue differentiation by the long non-coding RNA TINCR.

Kretz M, Siprashvili Z, Chu C, Webster DE, Zehnder A, Qu K, Lee CS, Flockhart RJ, Groff AF, Chow J, Johnston D, Kim GE, Spitale RC, Flynn RA, Zheng GX, Aiyer S, Raj A, Rinn JL, Chang HY, Khavari PA.

Nature. 2013 Jan 10;493(7431):231-5. doi: 10.1038/nature11661.


Identification of proteins binding coding and non-coding human RNAs using protein microarrays.

Siprashvili Z, Webster DE, Kretz M, Johnston D, Rinn JL, Chang HY, Khavari PA.

BMC Genomics. 2012 Nov 16;13:633. doi: 10.1186/1471-2164-13-633.


Transcriptome sequencing in Sezary syndrome identifies Sezary cell and mycosis fungoides-associated lncRNAs and novel transcripts.

Lee CS, Ungewickell A, Bhaduri A, Qu K, Webster DE, Armstrong R, Weng WK, Aros CJ, Mah A, Chen RO, Lin M, Sundram U, Chang HY, Kretz M, Kim YH, Khavari PA.

Blood. 2012 Oct 18;120(16):3288-97. doi: 10.1182/blood-2012-04-423061.


Genomic profiling of a human organotypic model of AEC syndrome reveals ZNF750 as an essential downstream target of mutant TP63.

Zarnegar BJ, Webster DE, Lopez-Pajares V, Vander Stoep Hunt B, Qu K, Yan KJ, Berk DR, Sen GL, Khavari PA.

Am J Hum Genet. 2012 Sep 7;91(3):435-43. doi: 10.1016/j.ajhg.2012.07.007.


BRAFV600E remodels the melanocyte transcriptome and induces BANCR to regulate melanoma cell migration.

Flockhart RJ, Webster DE, Qu K, Mascarenhas N, Kovalski J, Kretz M, Khavari PA.

Genome Res. 2012 Jun;22(6):1006-14. doi: 10.1101/gr.140061.112. Erratum in: Genome Res. 2012 Jul;22(7):1382.


ZNF750 is a p63 target gene that induces KLF4 to drive terminal epidermal differentiation.

Sen GL, Boxer LD, Webster DE, Bussat RT, Qu K, Zarnegar BJ, Johnston D, Siprashvili Z, Khavari PA.

Dev Cell. 2012 Mar 13;22(3):669-77. doi: 10.1016/j.devcel.2011.12.001.


Use of the wound-inducible NtQPT2 promoter from Nicotiana tabacum for production of a plant-made vaccine.

De Guzman G, Walmsley AM, Webster DE, Hamill JD.

Biotechnol Lett. 2012 Jun;34(6):1143-50. doi: 10.1007/s10529-012-0879-6.


Suppression of progenitor differentiation requires the long noncoding RNA ANCR.

Kretz M, Webster DE, Flockhart RJ, Lee CS, Zehnder A, Lopez-Pajares V, Qu K, Zheng GX, Chow J, Kim GE, Rinn JL, Chang HY, Siprashvili Z, Khavari PA.

Genes Dev. 2012 Feb 15;26(4):338-43. doi: 10.1101/gad.182121.111.


Production, characterisation and immunogenicity of a plant-made Plasmodium antigen--the 19 kDa C-terminal fragment of Plasmodium yoelii merozoite surface protein 1.

Ma C, Wang L, Webster DE, Campbell AE, Coppel RL.

Appl Microbiol Biotechnol. 2012 Apr;94(1):151-61. doi: 10.1007/s00253-011-3772-7.


Advanced glycation end products are direct modulators of β-cell function.

Coughlan MT, Yap FY, Tong DC, Andrikopoulos S, Gasser A, Thallas-Bonke V, Webster DE, Miyazaki J, Kay TW, Slattery RM, Kaye DM, Drew BG, Kingwell BA, Fourlanos S, Groop PH, Harrison LC, Knip M, Forbes JM.

Diabetes. 2011 Oct;60(10):2523-32. doi: 10.2337/db10-1033.


Post-translational modification of plant-made foreign proteins; glycosylation and beyond.

Webster DE, Thomas MC.

Biotechnol Adv. 2012 Mar-Apr;30(2):410-8. doi: 10.1016/j.biotechadv.2011.07.015. Review.


Hairy roots cultures from different Solanaceous species have varying capacities to produce E. coli B-subunit heat-labile toxin antigen.

De Guzman G, Walmsley AM, Webster DE, Hamill JD.

Biotechnol Lett. 2011 Dec;33(12):2495-502. doi: 10.1007/s10529-011-0710-9.


KIR receptor-ligand incompatibility predicts killing of osteosarcoma cell lines by allogeneic NK cells.

Delgado D, Webster DE, DeSantes KB, Durkin ET, Shaaban AF.

Pediatr Blood Cancer. 2010 Dec 15;55(7):1300-5. doi: 10.1002/pbc.22665.


Opioidergic mechanisms underlying the actions of Vitex agnus-castus L.

Webster DE, He Y, Chen SN, Pauli GF, Farnsworth NR, Wang ZJ.

Biochem Pharmacol. 2011 Jan 1;81(1):170-7. doi: 10.1016/j.bcp.2010.09.013.


Circulating high-molecular-weight RAGE ligands activate pathways implicated in the development of diabetic nephropathy.

Penfold SA, Coughlan MT, Patel SK, Srivastava PM, Sourris KC, Steer D, Webster DE, Thomas MC, MacIsaac RJ, Jerums G, Burrell LM, Cooper ME, Forbes JM.

Kidney Int. 2010 Aug;78(3):287-95. doi: 10.1038/ki.2010.134.

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