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Items: 1 to 20 of 218

1.

High-throughput Chemical Screening Identifies Focal Adhesion Kinase and Aurora Kinase B Inhibition as a Synergistic Treatment Combination in Ewing Sarcoma.

Wang S, Hwang EE, Guha R, O'Neill AF, Melong N, Veinotte CJ, Saur Conway A, Wuerthele K, Shen M, McKnight C, Alexe G, Lemieux ME, Wang A, Hughes E, Xu X, Boxer MB, Hall MD, Kung AL, Berman JN, Davis MI, Stegmaier K, Crompton BD.

Clin Cancer Res. 2019 Apr 12. pii: clincanres.0375.2017. doi: 10.1158/1078-0432.CCR-17-0375. [Epub ahead of print]

PMID:
30979745
2.

The past, present, and future of CRM1/XPO1 inhibitors.

Wang AY, Liu H.

Stem Cell Investig. 2019 Feb 25;6:6. doi: 10.21037/sci.2019.02.03. eCollection 2019. Review.

3.

A randomized clinical trial comparing early active motion programs: Earlier hand function, TAM, and orthotic satisfaction with a relative motion extension program for zones V and VI extensor tendon repairs.

Collocott SJF, Kelly E, Foster M, Myhr H, Wang A, Ellis RF.

J Hand Ther. 2019 Mar 21. pii: S0894-1130(18)30082-6. doi: 10.1016/j.jht.2018.10.003. [Epub ahead of print]

PMID:
30905495
4.

Semiautomatic carotid intraplaque hemorrhage volume measurement using 3D carotid MRI.

Liu J, Sun J, Balu N, Ferguson MS, Wang J, Kerwin WS, Hippe DS, Wang A, Hatsukami TS, Yuan C.

J Magn Reson Imaging. 2019 Mar 12. doi: 10.1002/jmri.26698. [Epub ahead of print]

PMID:
30861249
5.

Impact of Polymer-TLR-7/8 Agonist (Adjuvant) Morphology on the Potency and Mechanism of CD8 T Cell Induction.

Lynn GM, Chytil P, Francica JR, Lagová A, Kueberuwa G, Ishizuka AS, Zaidi N, Ramirez-Valdez RA, Blobel NJ, Baharom F, Leal J, Wang AQ, Gerner MY, Etrych T, Ulbrich K, Seymour LW, Seder RA, Laga R.

Biomacromolecules. 2019 Feb 11;20(2):854-870. doi: 10.1021/acs.biomac.8b01473. Epub 2019 Jan 22.

PMID:
30608149
6.

Key Characteristics Approach to Carcinogenic Hazard Identification.

Guyton KZ, Rieswijk L, Wang A, Chiu WA, Smith MT.

Chem Res Toxicol. 2018 Dec 17;31(12):1290-1292. doi: 10.1021/acs.chemrestox.8b00321. Epub 2018 Dec 6.

PMID:
30521319
7.

Screening for Elevated Blood Lead Levels: False-Positive Rates of Tests on Capillary Samples, Minnesota, 2011-2017.

Wang A, Rezania Z, Haugen KMB, Baertlein L, Yendell SJ.

J Public Health Manag Pract. 2019 Jan/Feb;25 Suppl 1, Lead Poisoning Prevention:S44-S50. doi: 10.1097/PHH.0000000000000879.

PMID:
30507769
8.

Mouse, rat, and dog bioavailability and mouse oral antidepressant efficacy of ( 2R,6R)-hydroxynorketamine.

Highland JN, Morris PJ, Zanos P, Lovett J, Ghosh S, Wang AQ, Zarate CA Jr, Thomas CJ, Moaddel R, Gould TD.

J Psychopharmacol. 2018 Nov 29:269881118812095. doi: 10.1177/0269881118812095. [Epub ahead of print]

PMID:
30488740
9.

Pharmacokinetic evaluation of the PNC disassembler metarrestin in wild-type and Pdx1-Cre;LSL-KrasG12D/+;Tp53R172H/+ (KPC) mice, a genetically engineered model of pancreatic cancer.

Vilimas T, Wang AQ, Patnaik S, Hughes EA, Singleton MD, Knotts Z, Li D, Frankowski K, Schlomer JJ, Guerin TM, Springer S, Drennan C, Dextras C, Wang C, Gilbert D, Southall N, Ferrer M, Huang S, Kozlov S, Marugan J, Xu X, Rudloff U.

Cancer Chemother Pharmacol. 2018 Dec;82(6):1067-1080. doi: 10.1007/s00280-018-3699-0. Epub 2018 Oct 10.

10.

Discovery and lead identification of quinazoline-based BRD4 inhibitors.

Yang SM, Urban DJ, Yoshioka M, Strovel JW, Fletcher S, Wang AQ, Xu X, Shah P, Hu X, Hall MD, Jadhav A, Maloney DJ.

Bioorg Med Chem Lett. 2018 Nov 15;28(21):3483-3488. doi: 10.1016/j.bmcl.2018.08.039. Epub 2018 Aug 31.

PMID:
30268702
11.

Discovery of 3-(4-sulfamoylnaphthyl)pyrazolo[1,5-a]pyrimidines as potent and selective ALK2 inhibitors.

Jiang JK, Huang X, Shamim K, Patel PR, Lee A, Wang AQ, Nguyen K, Tawa G, Cuny GD, Yu PB, Zheng W, Xu X, Sanderson P, Huang W.

Bioorg Med Chem Lett. 2018 Nov 1;28(20):3356-3362. doi: 10.1016/j.bmcl.2018.09.006. Epub 2018 Sep 6.

PMID:
30227946
12.

Cervical Spine Osteomyelitis: A Systematic Review of Instrumented Fusion in the Modern Era.

Wang AJ, Huang KT, Smith TR, Lu Y, Chi JH, Groff MW, Zaidi HA.

World Neurosurg. 2018 Dec;120:e562-e572. doi: 10.1016/j.wneu.2018.08.129. Epub 2018 Aug 28.

PMID:
30165226
13.

In Vivo Efficacy of VT-1129 against Experimental Cryptococcal Meningitis with the Use of a Loading Dose-Maintenance Dose Administration Strategy.

Wiederhold NP, Xu X, Wang A, Najvar LK, Garvey EP, Ottinger EA, Alimardanov A, Cradock J, Behnke M, Hoekstra WJ, Brand SR, Schotzinger RJ, Jaramillo R, Olivo M, Kirkpatrick WR, Patterson TF.

Antimicrob Agents Chemother. 2018 Oct 24;62(11). pii: e01315-18. doi: 10.1128/AAC.01315-18. Print 2018 Nov.

14.

Optimization of the first small-molecule relaxin/insulin-like family peptide receptor (RXFP1) agonists: Activation results in an antifibrotic gene expression profile.

Wilson KJ, Xiao J, Chen CZ, Huang Z, Agoulnik IU, Ferrer M, Southall N, Hu X, Zheng W, Xu X, Wang A, Myhr C, Barnaeva E, George ER, Agoulnik AI, Marugan JJ.

Eur J Med Chem. 2018 Aug 5;156:79-92. doi: 10.1016/j.ejmech.2018.06.008. Epub 2018 Jun 7.

PMID:
30006176
15.

Classifying Clinical Trial Eligibility Criteria to Facilitate Phased Cohort Identification Using Clinical Data Repositories.

Wang AY, Lancaster WJ, Wyatt MC, Rasmussen LV, Fort DG, Cimino JJ.

AMIA Annu Symp Proc. 2018 Apr 16;2017:1754-1763. eCollection 2017.

16.

Discovery of Orally Bioavailable, Quinoline-Based Aldehyde Dehydrogenase 1A1 (ALDH1A1) Inhibitors with Potent Cellular Activity.

Yang SM, Martinez NJ, Yasgar A, Danchik C, Johansson C, Wang Y, Baljinnyam B, Wang AQ, Xu X, Shah P, Cheff D, Wang XS, Roth J, Lal-Nag M, Dunford JE, Oppermann U, Vasiliou V, Simeonov A, Jadhav A, Maloney DJ.

J Med Chem. 2018 Jun 14;61(11):4883-4903. doi: 10.1021/acs.jmedchem.8b00270. Epub 2018 May 31.

17.

Ketogenic diet enhances neurovascular function with altered gut microbiome in young healthy mice.

Ma D, Wang AC, Parikh I, Green SJ, Hoffman JD, Chlipala G, Murphy MP, Sokola BS, Bauer B, Hartz AMS, Lin AL.

Sci Rep. 2018 Apr 27;8(1):6670. doi: 10.1038/s41598-018-25190-5.

18.

Rates of depressive symptoms among pharmacy residents.

Williams E, Martin SL, Fabrikant A, Wang A, Pojasek M.

Am J Health Syst Pharm. 2018 Mar 1;75(5):292-297. doi: 10.2146/ajhp161008.

PMID:
29472510
19.

Endoscopic eradication therapy for patients with Barrett's esophagus-associated dysplasia and intramucosal cancer.

Standards of Practice Committee, Wani S, Qumseya B, Sultan S, Agrawal D, Chandrasekhara V, Harnke B, Kothari S, McCarter M, Shaukat A, Wang A, Yang J, Dewitt J.

Gastrointest Endosc. 2018 Apr;87(4):907-931.e9. doi: 10.1016/j.gie.2017.10.011. Epub 2018 Feb 15. No abstract available.

PMID:
29397943
20.

Preclinical Pharmacological Development of Chlorcyclizine Derivatives for the Treatment of Hepatitis C Virus Infection.

Rolt A, Le D, Hu Z, Wang AQ, Shah P, Singleton M, Hughes E, Dulcey AE, He S, Imamura M, Uchida T, Chayama K, Xu X, Marugan JJ, Liang TJ.

J Infect Dis. 2018 May 5;217(11):1761-1769. doi: 10.1093/infdis/jiy039.

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