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Transfemoral implantation of the ACURATE neo prosthesis using a low-profile expandable introducer system: A multicenter registry.

Kim WK, Brinkert M, Mangner N, Gatto F, Husser O, Renker M, Liebetrau C, Gasior T, Doss M, Walther T, Hamm C, Linke A, Toggweiler S, Möllmann H.

Int J Cardiol. 2019 Jan 25. pii: S0167-5273(18)34810-1. doi: 10.1016/j.ijcard.2019.01.081. [Epub ahead of print]


The DEDICATE Trial: An independent all-comers trial of transcatheter aortic valve implantation vs. surgical aortic valve replacement in patients at low to intermediate operative risk is recruiting patients.

Seiffert M, Walther T, Hamm C, Falk V, Frey N, Thiele H, Hagl C, Landmesser U, Borger M, Massberg S, Reichenspurner H, Baumgartner H, Blankenberg S, Cremer J.

Eur Heart J. 2019 Jan 21;40(4):331-333. doi: 10.1093/eurheartj/ehy851. No abstract available.


The unfolded protein response and endoplasmic reticulum protein targeting machineries converge on the stress sensor IRE1.

Acosta-Alvear D, Karagöz GE, Fröhlich F, Li H, Walther TC, Walter P.

Elife. 2018 Dec 24;7. pii: e43036. doi: 10.7554/eLife.43036.


Patients at Intermediate Surgical Risk Undergoing Isolated Interventional or Surgical Aortic Valve Implantation for Severe Symptomatic Aortic Valve Stenosis.

Werner N, Zahn R, Beckmann A, Bauer T, Bleiziffer S, Hamm CW, Berkeredjian R, Berkowitsch A, Mohr FW, Landwehr S, Katus HA, Harringer W, Ensminger S, Frerker C, Möllmann H, Walther T, Schneider S, Lange R; GARY Executive Board.

Circulation. 2018 Dec 4;138(23):2611-2623. doi: 10.1161/CIRCULATIONAHA.117.033048.


Lipidomic Analysis of α-Synuclein Neurotoxicity Identifies Stearoyl CoA Desaturase as a Target for Parkinson Treatment.

Fanning S, Haque A, Imberdis T, Baru V, Barrasa MI, Nuber S, Termine D, Ramalingam N, Ho GPH, Noble T, Sandoe J, Lou Y, Landgraf D, Freyzon Y, Newby G, Soldner F, Terry-Kantor E, Kim TE, Hofbauer HF, Becuwe M, Jaenisch R, Pincus D, Clish CB, Walther TC, Farese RV Jr, Srinivasan S, Welte MA, Kohlwein SD, Dettmer U, Lindquist S, Selkoe D.

Mol Cell. 2018 Dec 1. pii: S1097-2765(18)30998-5. doi: 10.1016/j.molcel.2018.11.028. [Epub ahead of print]


CRISPR-Cas9-based Genome Engineering to Generate Jurkat Reporter Models for HIV-1 Infection with Selected Proviral Integration Sites.

Bialek JK, Walther T, Hauber J, Lange UC.

J Vis Exp. 2018 Nov 14;(141). doi: 10.3791/58572.


Scaffolds in a shell-a new approach combining one-photon and two-photon polymerization.

Trautmann A, Götzendorfer B, Walther T, Hellmann R.

Opt Express. 2018 Nov 12;26(23):29659-29668. doi: 10.1364/OE.26.029659.


The transient production of anti-TNF-α antibody Adalimumab and a comparison of its characterization to the biosimilar Cinorra.

Tabasinezhad M, Mahboudi F, Wenzel W, Rahimi H, Walther TH, Blattner C, Omidinia E.

Protein Expr Purif. 2019 Mar;155:59-65. doi: 10.1016/j.pep.2018.11.006. Epub 2018 Nov 22.


Patients at low surgical risk as defined by the Society of Thoracic Surgeons Score undergoing isolated interventional or surgical aortic valve implantation: in-hospital data and 1-year results from the German Aortic Valve Registry (GARY).

Bekeredjian R, Szabo G, Balaban Ü, Bleiziffer S, Bauer T, Ensminger S, Frerker C, Herrmann E, Beyersdorf F, Hamm C, Beckmann A, Möllmann H, Karck M, Katus HA, Walther T.

Eur Heart J. 2018 Nov 16. doi: 10.1093/eurheartj/ehy699. [Epub ahead of print]


Rational engineering of a malate dehydrogenase for microbial production of 2,4-dihydroxybutyric acid via homoserine pathway.

Frazão CJR, Topham CM, Malbert Y, François JM, Walther T.

Biochem J. 2018 Dec 12;475(23):3887-3901. doi: 10.1042/BCJ20180765.


Organellar Proteomics and Phospho-Proteomics Reveal Subcellular Reorganization in Diet-Induced Hepatic Steatosis.

Krahmer N, Najafi B, Schueder F, Quagliarini F, Steger M, Seitz S, Kasper R, Salinas F, Cox J, Uhlenhaut NH, Walther TC, Jungmann R, Zeigerer A, Borner GHH, Mann M.

Dev Cell. 2018 Oct 22;47(2):205-221.e7. doi: 10.1016/j.devcel.2018.09.017.


Cryo-electron microscopy structure of the lipid droplet-formation protein seipin.

Sui X, Arlt H, Brock KP, Lai ZW, DiMaio F, Marks DS, Liao M, Farese RV Jr, Walther TC.

J Cell Biol. 2018 Dec 3;217(12):4080-4091. doi: 10.1083/jcb.201809067. Epub 2018 Oct 16.


Cardiac resynchronization therapy with wireless left ventricular endocardial pacing: is this the direction to go?

Holubec T, Beckers J, Holubcova Z, Walter V, Walther T.

Cardiovasc Diagn Ther. 2018 Aug;8(4):534-537. doi: 10.21037/cdt.2018.05.08. No abstract available.


Progranulin in the hematopoietic compartment protects mice from atherosclerosis.

Nguyen AD, Nguyen TA, Singh RK, Eberlé D, Zhang J, Abate JP, Robles A, Koliwad S, Huang EJ, Maxfield FR, Walther TC, Farese RV Jr.

Atherosclerosis. 2018 Oct;277:145-154. doi: 10.1016/j.atherosclerosis.2018.08.042. Epub 2018 Aug 30.


Development of a Metabolite Sensor for High-Throughput Detection of Aldehydes in Escherichia Coli.

Frazão CR, Maton V, François JM, Walther T.

Front Bioeng Biotechnol. 2018 Aug 23;6:118. doi: 10.3389/fbioe.2018.00118. eCollection 2018.


Fine needle aspirates of kidneys: a promising tool for RNA sequencing in native and transplanted kidneys.

Eikrem Ø, Walther TC, Flatberg A, Beisvag V, Strauss P, Farstad M, Beisland C, Koch E, Mueller TF, Marti HP.

BMC Nephrol. 2018 Sep 5;19(1):221. doi: 10.1186/s12882-018-1012-4.


Neprilysin degrades murine Amyloid-β (Aβ) more efficiently than human Aβ: Further implication for species-specific amyloid accumulation.

Becker M, Moore A, Naughton M, Boland B, Siems WE, Walther T.

Neurosci Lett. 2018 Nov 1;686:74-79. doi: 10.1016/j.neulet.2018.08.028. Epub 2018 Aug 23.


Self-consistent absorption correction for quantifying very noisy X-ray maps: group III nitride nanowires as an example.

Wang X, Bai J, Walther T.

J Microsc. 2018 Nov;272(2):111-122. doi: 10.1111/jmi.12751. Epub 2018 Aug 21.


Drug-based perturbation screen uncovers synergistic drug combinations in Burkitt lymphoma.

Tomska K, Kurilov R, Lee KS, Hüllein J, Lukas M, Sellner L, Walther T, Wagner L, Oleś M, Brors B, Huber W, Zenz T.

Sci Rep. 2018 Aug 13;8(1):12046. doi: 10.1038/s41598-018-30509-3.


Clonal diversity predicts adverse outcome in chronic lymphocytic leukemia.

Leeksma AC, Taylor J, Wu B, Gardner JR, He J, Nahas M, Gonen M, Alemayehu WG, Te Raa D, Walther T, Hüllein J, Dietrich S, Claus R, de Boer F, de Heer K, Dubois J, Dampmann M, Dürig J, van Oers MHJ, Geisler CH, Eldering E, Levine RL, Miller V, Mughal T, Lamanna N, Frattini MG, Heaney ML, Zelenetz A, Zenz T, Abdel-Wahab O, Kater AP.

Leukemia. 2019 Feb;33(2):390-402. doi: 10.1038/s41375-018-0215-9. Epub 2018 Jul 23.


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