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Items: 1 to 20 of 60


Daily associations between alcohol and sexual behavior in young adults.

Simons JS, Simons RM, Maisto SA, Hahn AM, Walters KJ.

Exp Clin Psychopharmacol. 2018 Feb;26(1):36-48. doi: 10.1037/pha0000163.


Structure of the Rpn13-Rpn2 complex provides insights for Rpn13 and Uch37 as anticancer targets.

Lu X, Nowicka U, Sridharan V, Liu F, Randles L, Hymel D, Dyba M, Tarasov SG, Tarasova NI, Zhao XZ, Hamazaki J, Murata S, Burke TR Jr, Walters KJ.

Nat Commun. 2017 Jun 9;8:15540. doi: 10.1038/ncomms15540.


A pharmacotherapy review of the novel, oral antithrombotics.

Walters KJ, Meador A, Galdo JA, Ciarrocca K.

Spec Care Dentist. 2017 Mar;37(2):62-70. doi: 10.1111/scd.12207. Epub 2016 Oct 22. Review.


Novel TDP2-ubiquitin interactions and their importance for the repair of topoisomerase II-mediated DNA damage.

Rao T, Gao R, Takada S, Al Abo M, Chen X, Walters KJ, Pommier Y, Aihara H.

Nucleic Acids Res. 2016 Dec 1;44(21):10201-10215. Epub 2016 Aug 19.


Structures of Rpn1 T1:Rad23 and hRpn13:hPLIC2 Reveal Distinct Binding Mechanisms between Substrate Receptors and Shuttle Factors of the Proteasome.

Chen X, Randles L, Shi K, Tarasov SG, Aihara H, Walters KJ.

Structure. 2016 Aug 2;24(8):1257-1270. doi: 10.1016/j.str.2016.05.018. Epub 2016 Jul 7.


(1)H, (15)N, (13)C resonance assignments for Saccharomyces cerevisiae Rad23 UBL domain.

Chen X, Walters KJ.

Biomol NMR Assign. 2016 Oct;10(2):291-5. doi: 10.1007/s12104-016-9686-7. Epub 2016 May 17.


Characterization of Dynamic UbR-Proteasome Subcomplexes by In vivo Cross-linking (X) Assisted Bimolecular Tandem Affinity Purification (XBAP) and Label-free Quantitation.

Yu C, Yang Y, Wang X, Guan S, Fang L, Liu F, Walters KJ, Kaiser P, Huang L.

Mol Cell Proteomics. 2016 Jul;15(7):2279-92. doi: 10.1074/mcp.M116.058271. Epub 2016 Apr 25.


Individual Versus Team-Based Financial Incentives to Increase Physical Activity: A Randomized, Controlled Trial.

Patel MS, Asch DA, Rosin R, Small DS, Bellamy SL, Eberbach K, Walters KJ, Haff N, Lee SM, Wesby L, Hoffer K, Shuttleworth D, Taylor DH, Hilbert V, Zhu J, Yang L, Wang X, Volpp KG.

J Gen Intern Med. 2016 Jul;31(7):746-54. doi: 10.1007/s11606-016-3627-0. Epub 2016 Mar 14.


Myosin VI Contains a Compact Structural Motif that Binds to Ubiquitin Chains.

He F, Wollscheid HP, Nowicka U, Biancospino M, Valentini E, Ehlinger A, Acconcia F, Magistrati E, Polo S, Walters KJ.

Cell Rep. 2016 Mar 22;14(11):2683-94. doi: 10.1016/j.celrep.2016.01.079. Epub 2016 Mar 10.


Diverse functions of myosin VI elucidated by an isoform-specific α-helix domain.

Wollscheid HP, Biancospino M, He F, Magistrati E, Molteni E, Lupia M, Soffientini P, Rottner K, Cavallaro U, Pozzoli U, Mapelli M, Walters KJ, Polo S.

Nat Struct Mol Biol. 2016 Apr;23(4):300-308. doi: 10.1038/nsmb.3187. Epub 2016 Mar 7.


Rpn1 provides adjacent receptor sites for substrate binding and deubiquitination by the proteasome.

Shi Y, Chen X, Elsasser S, Stocks BB, Tian G, Lee BH, Shi Y, Zhang N, de Poot SA, Tuebing F, Sun S, Vannoy J, Tarasov SG, Engen JR, Finley D, Walters KJ.

Science. 2016 Feb 19;351(6275). pii: aad9421. doi: 10.1126/science.aad9421.


The Proteasome Ubiquitin Receptor hRpn13 and Its Interacting Deubiquitinating Enzyme Uch37 Are Required for Proper Cell Cycle Progression.

Randles L, Anchoori RK, Roden RB, Walters KJ.

J Biol Chem. 2016 Apr 15;291(16):8773-83. doi: 10.1074/jbc.M115.694588. Epub 2016 Feb 23.


Mycobacterium tuberculosis copper-regulated protein SocB is an intrinsically disordered protein that folds upon interaction with a synthetic phospholipid bilayer.

Nowicka U, Hoffman M, Randles L, Shi X, Khavrutskii L, Stefanisko K, Tarasova NI, Darwin KH, Walters KJ.

Proteins. 2016 Feb;84(2):193-200. doi: 10.1002/prot.24970. Epub 2015 Dec 29.


Gates, Channels, and Switches: Elements of the Proteasome Machine.

Finley D, Chen X, Walters KJ.

Trends Biochem Sci. 2016 Jan;41(1):77-93. doi: 10.1016/j.tibs.2015.10.009. Epub 2015 Nov 28. Review.


A High Affinity hRpn2-Derived Peptide That Displaces Human Rpn13 from Proteasome in 293T Cells.

Lu X, Liu F, Durham SE, Tarasov SG, Walters KJ.

PLoS One. 2015 Oct 14;10(10):e0140518. doi: 10.1371/journal.pone.0140518. eCollection 2015.


Artificial targeting of misfolded cytosolic proteins to endoplasmic reticulum as a mechanism for clearance.

Liu F, Koepp DM, Walters KJ.

Sci Rep. 2015 Jul 14;5:12088. doi: 10.1038/srep12088.


Structural plasticity allows UCH37 to be primed by RPN13 or locked down by INO80G.

Chen X, Walters KJ.

Mol Cell. 2015 Mar 5;57(5):767-768. doi: 10.1016/j.molcel.2015.02.025.


A bis-benzylidine piperidone targeting proteasome ubiquitin receptor RPN13/ADRM1 as a therapy for cancer.

Anchoori RK, Karanam B, Peng S, Wang JW, Jiang R, Tanno T, Orlowski RZ, Matsui W, Zhao M, Rudek MA, Hung CF, Chen X, Walters KJ, Roden RB.

Cancer Cell. 2013 Dec 9;24(6):791-805. doi: 10.1016/j.ccr.2013.11.001.


Structural insights into proteasome activation by the 19S regulatory particle.

Ehlinger A, Walters KJ.

Biochemistry. 2013 May 28;52(21):3618-28. doi: 10.1021/bi400417a. Epub 2013 May 14.


Conformational dynamics of the Rpt6 ATPase in proteasome assembly and Rpn14 binding.

Ehlinger A, Park S, Fahmy A, Lary JW, Cole JL, Finley D, Walters KJ.

Structure. 2013 May 7;21(5):753-65. doi: 10.1016/j.str.2013.02.021. Epub 2013 Apr 4.

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