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Items: 1 to 20 of 24


Transcriptome Analysis of Pig In Vivo, In Vitro-Fertilized, and Nuclear Transfer Blastocyst-Stage Embryos Treated with Histone Deacetylase Inhibitors Postfusion and Activation Reveals Changes in the Lysosomal Pathway.

Whitworth KM, Mao J, Lee K, Spollen WG, Samuel MS, Walters EM, Spate LD, Prather RS.

Cell Reprogram. 2015 Aug;17(4):243-58. doi: 10.1089/cell.2015.0022.


Engineering protein processing of the mammary gland to produce abundant hemophilia B therapy in milk.

Zhao J, Xu W, Ross JW, Walters EM, Butler SP, Whyte JJ, Kelso L, Fatemi M, Vanderslice NC, Giroux K, Spate LD, Samuel MS, Murphy CN, Wells KD, Masiello NC, Prather RS, Velander WH.

Sci Rep. 2015 Sep 21;5:14176. doi: 10.1038/srep14176.


Pig oocyte activation using a Zn²⁺ chelator, TPEN.

Lee K, Davis A, Zhang L, Ryu J, Spate LD, Park KW, Samuel MS, Walters EM, Murphy CN, Machaty Z, Prather RS.

Theriogenology. 2015 Oct 1;84(6):1024-32. doi: 10.1016/j.theriogenology.2015.05.036. Epub 2015 Jun 12.


A Genetic Porcine Model of Cancer.

Schook LB, Collares TV, Hu W, Liang Y, Rodrigues FM, Rund LA, Schachtschneider KM, Seixas FK, Singh K, Wells KD, Walters EM, Prather RS, Counter CM.

PLoS One. 2015 Jul 1;10(7):e0128864. doi: 10.1371/journal.pone.0128864. eCollection 2015.


Targeted disruption of CD1d prevents NKT cell development in pigs.

Yang G, Artiaga BL, Hackmann TJ, Samuel MS, Walters EM, Salek-Ardakani S, Driver JP.

Mamm Genome. 2015 Jun;26(5-6):264-70. doi: 10.1007/s00335-015-9564-0. Epub 2015 May 1.


Impairment of preimplantation porcine embryo development by histone demethylase KDM5B knockdown through disturbance of bivalent H3K4me3-H3K27me3 modifications.

Huang J, Zhang H, Wang X, Dobbs KB, Yao J, Qin G, Whitworth K, Walters EM, Prather RS, Zhao J.

Biol Reprod. 2015 Mar;92(3):72. doi: 10.1095/biolreprod.114.122762. Epub 2015 Jan 21.


Oxamflatin treatment enhances cloned porcine embryo development and nuclear reprogramming.

Mao J, Zhao MT, Whitworth KM, Spate LD, Walters EM, O'Gorman C, Lee K, Samuel MS, Murphy CN, Wells K, Rivera RM, Prather RS.

Cell Reprogram. 2015 Feb;17(1):28-40. doi: 10.1089/cell.2014.0075. Epub 2014 Dec 30.


Use of the CRISPR/Cas9 system to produce genetically engineered pigs from in vitro-derived oocytes and embryos.

Whitworth KM, Lee K, Benne JA, Beaton BP, Spate LD, Murphy SL, Samuel MS, Mao J, O'Gorman C, Walters EM, Murphy CN, Driver J, Mileham A, McLaren D, Wells KD, Prather RS.

Biol Reprod. 2014 Sep;91(3):78. doi: 10.1095/biolreprod.114.121723. Epub 2014 Aug 6.


Engraftment of human iPS cells and allogeneic porcine cells into pigs with inactivated RAG2 and accompanying severe combined immunodeficiency.

Lee K, Kwon DN, Ezashi T, Choi YJ, Park C, Ericsson AC, Brown AN, Samuel MS, Park KW, Walters EM, Kim DY, Kim JH, Franklin CL, Murphy CN, Roberts RM, Prather RS, Kim JH.

Proc Natl Acad Sci U S A. 2014 May 20;111(20):7260-5. doi: 10.1073/pnas.1406376111. Epub 2014 May 5.


Interaction of photoperiod and vernalization determines flowering time of Brachypodium distachyon.

Ream TS, Woods DP, Schwartz CJ, Sanabria CP, Mahoy JA, Walters EM, Kaeppler HF, Amasino RM.

Plant Physiol. 2014 Feb;164(2):694-709. doi: 10.1104/pp.113.232678. Epub 2013 Dec 19.


An organic acid based counter selection system for cyanobacteria.

Begemann MB, Zess EK, Walters EM, Schmitt EF, Markley AL, Pfleger BF.

PLoS One. 2013 Oct 1;8(10):e76594. doi: 10.1371/journal.pone.0076594. eCollection 2013.


Xenopus egg extract treatment reduced global DNA methylation of donor cells and enhanced somatic cell nuclear transfer embryo development in pigs.

Yang X, Mao J, Walters EM, Zhao MT, Teson J, Lee K, Prather RS.

Biores Open Access. 2012 Apr;1(2):79-87. doi: 10.1089/biores.2012.0214.


Completion of the swine genome will simplify the production of swine as a large animal biomedical model.

Walters EM, Wolf E, Whyte JJ, Mao J, Renner S, Nagashima H, Kobayashi E, Zhao J, Wells KD, Critser JK, Riley LK, Prather RS.

BMC Med Genomics. 2012 Nov 15;5:55. doi: 10.1186/1755-8794-5-55.


Effects of combined treatment of MG132 and scriptaid on early and term development of porcine somatic cell nuclear transfer embryos.

Mao J, Tessanne K, Whitworth KM, Spate LD, Walters EM, Samuel MS, Murphy CN, Tracy L, Zhao J, Prather RS.

Cell Reprogram. 2012 Oct;14(5):385-9. doi: 10.1089/cell.2012.0018. Epub 2012 Aug 23.


Emerging applications of sperm, embryo and somatic cell cryopreservation in maintenance, relocation and rederivation of swine genetics.

Men H, Walters EM, Nagashima H, Prather RS.

Theriogenology. 2012 Nov;78(8):1720-9. doi: 10.1016/j.theriogenology.2012.06.003. Epub 2012 Aug 13. Review.


Regulation of oocyte mitochondrial DNA copy number by follicular fluid, EGF, and neuregulin 1 during in vitro maturation affects embryo development in pigs.

Mao J, Whitworth KM, Spate LD, Walters EM, Zhao J, Prather RS.

Theriogenology. 2012 Sep 1;78(4):887-97. doi: 10.1016/j.theriogenology.2012.04.002. Epub 2012 May 22.


Birth of piglets from in vitro-produced, zona-intact porcine embryos vitrified in a closed system.

Men H, Zhao C, Si W, Murphy CN, Spate L, Liu Y, Walters EM, Samuel MS, Prather RS, Critser JK.

Theriogenology. 2011 Jul 15;76(2):280-9. doi: 10.1016/j.theriogenology.2011.02.004. Epub 2011 Mar 31.


Gene targeting with zinc finger nucleases to produce cloned eGFP knockout pigs.

Whyte JJ, Zhao J, Wells KD, Samuel MS, Whitworth KM, Walters EM, Laughlin MH, Prather RS.

Mol Reprod Dev. 2011 Jan;78(1):2. doi: 10.1002/mrd.21271. No abstract available.


Vascular endothelium-specific overexpression of human catalase in cloned pigs.

Whyte JJ, Samuel M, Mahan E, Padilla J, Simmons GH, Arce-Esquivel AA, Bender SB, Whitworth KM, Hao YH, Murphy CN, Walters EM, Prather RS, Laughlin MH.

Transgenic Res. 2011 Oct;20(5):989-1001. doi: 10.1007/s11248-010-9473-7. Epub 2010 Dec 18.


Histone deacetylase inhibitors improve in vitro and in vivo developmental competence of somatic cell nuclear transfer porcine embryos.

Zhao J, Hao Y, Ross JW, Spate LD, Walters EM, Samuel MS, Rieke A, Murphy CN, Prather RS.

Cell Reprogram. 2010 Feb;12(1):75-83. doi: 10.1089/cell.2009.0038.

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