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Items: 1 to 20 of 463

1.

Dihydromyricetin exerts a rapid antidepressant-like effect in association with enhancement of BDNF expression and inhibition of neuroinflammation.

Ren Z, Yan P, Zhu L, Yang H, Zhao Y, Kirby BP, Waddington JL, Zhen X.

Psychopharmacology (Berl). 2017 Oct 20. doi: 10.1007/s00213-017-4761-z. [Epub ahead of print]

PMID:
29058041
2.

Dapsone and Nitroso Dapsone Activation of Naı̈ve T-Cells from Healthy Donors.

Alzahrani A, Ogese M, Meng X, Waddington JC, Tailor A, Farrell J, Maggs JL, Betts C, Park BK, Naisbitt D.

Chem Res Toxicol. 2017 Oct 31. doi: 10.1021/acs.chemrestox.7b00263. [Epub ahead of print]

PMID:
29045131
3.

Activation of AMPK/mTORC1-Mediated Autophagy by Metformin Reverses Clk1 Deficiency-Sensitized Dopaminergic Neuronal Death.

Yan Q, Han C, Wang G, Waddington JL, Zheng L, Zhen X.

Mol Pharmacol. 2017 Dec;92(6):640-652. doi: 10.1124/mol.117.109512. Epub 2017 Oct 12.

PMID:
29025968
4.

Stimulation of accumbal GABAA receptors inhibits delta2-, but not delta1-, opioid receptor-mediated dopamine efflux in the nucleus accumbens of freely moving rats.

Aono Y, Kiguchi Y, Watanabe Y, Waddington JL, Saigusa T.

Eur J Pharmacol. 2017 Nov 15;815:18-25. doi: 10.1016/j.ejphar.2017.09.019. Epub 2017 Sep 18.

PMID:
28923348
5.

Modelling the neuromotor abnormalities of psychotic illness: Putative mechanisms and systems dysfunction.

Waddington JL, O'Tuathaigh CM.

Schizophr Res. 2017 Aug 31. pii: S0920-9964(17)30499-1. doi: 10.1016/j.schres.2017.08.022. [Epub ahead of print]

PMID:
28867516
6.

Translating advances in the molecular basis of schizophrenia into novel cognitive treatment strategies.

O'Tuathaigh CMP, Moran PM, Zhen XC, Waddington JL.

Br J Pharmacol. 2017 Oct;174(19):3173-3190. doi: 10.1111/bph.13938. Epub 2017 Aug 3. Review.

PMID:
28667666
7.
8.

Specialized Information Processing Deficits and Distinct Metabolomic Profiles Following TM-Domain Disruption of Nrg1.

O'Tuathaigh CMP, Mathur N, O'Callaghan MJ, MacIntyre L, Harvey R, Lai D, Waddington JL, Pickard BS, Watson DG, Moran PM.

Schizophr Bull. 2017 Sep 1;43(5):1100-1113. doi: 10.1093/schbul/sbw189.

9.

Genetic correlation between amyotrophic lateral sclerosis and schizophrenia.

McLaughlin RL, Schijven D, van Rheenen W, van Eijk KR, O'Brien M, Kahn RS, Ophoff RA, Goris A, Bradley DG, Al-Chalabi A, van den Berg LH, Luykx JJ, Hardiman O, Veldink JH; Project MinE GWAS Consortium; Schizophrenia Working Group of the Psychiatric Genomics Consortium.

Nat Commun. 2017 Mar 21;8:14774. doi: 10.1038/ncomms14774.

10.

Occurrence and co-occurrence of hallucinations by modality in schizophrenia-spectrum disorders.

McCarthy-Jones S, Smailes D, Corvin A, Gill M, Morris DW, Dinan TG, Murphy KC, Anthony O Neill F, Waddington JL, Australian Schizophrenia Research Bank, Donohoe G, Dudley R.

Psychiatry Res. 2017 Jun;252:154-160. doi: 10.1016/j.psychres.2017.01.102. Epub 2017 Feb 24.

PMID:
28273630
11.

Semaphorin 6A knockout mice display abnormalities across ethologically-based topographies of exploration and in motor learning.

Håkansson K, Runker AE, O'Sullivan GJ, Mitchell KJ, Waddington JL, O'Tuathaigh CM.

Neurosci Lett. 2017 Feb 22;641:70-76. doi: 10.1016/j.neulet.2017.01.043. Epub 2017 Jan 18.

PMID:
28109776
12.

Dysregulation of Specialized Delay/Interference-Dependent Working Memory Following Loss of Dysbindin-1A in Schizophrenia-Related Phenotypes.

Petit EI, Michalak Z, Cox R, O'Tuathaigh CM, Clarke N, Tighe O, Talbot K, Blake D, Joel J, Shaw A, Sheardown SA, Morrison AD, Wilson S, Shapland EM, Henshall DC, Kew JN, Kirby BP, Waddington JL.

Neuropsychopharmacology. 2017 May;42(6):1349-1360. doi: 10.1038/npp.2016.282. Epub 2016 Dec 16.

PMID:
27986973
13.

Altered cytokine profile, pain sensitivity, and stress responsivity in mice with co-disruption of the developmental genes Neuregulin-1×DISC1.

Desbonnet L, Cox R, Tighe O, Lai D, Harvey RP, Waddington JL, O'Tuathaigh CM.

Behav Brain Res. 2017 Mar 1;320:113-118. doi: 10.1016/j.bbr.2016.11.049. Epub 2016 Dec 1.

PMID:
27916686
14.

Contribution of copy number variants to schizophrenia from a genome-wide study of 41,321 subjects.

Marshall CR, Howrigan DP, Merico D, Thiruvahindrapuram B, Wu W, Greer DS, Antaki D, Shetty A, Holmans PA, Pinto D, Gujral M, Brandler WM, Malhotra D, Wang Z, Fajarado KVF, Maile MS, Ripke S, Agartz I, Albus M, Alexander M, Amin F, Atkins J, Bacanu SA, Belliveau RA Jr, Bergen SE, Bertalan M, Bevilacqua E, Bigdeli TB, Black DW, Bruggeman R, Buccola NG, Buckner RL, Bulik-Sullivan B, Byerley W, Cahn W, Cai G, Cairns MJ, Campion D, Cantor RM, Carr VJ, Carrera N, Catts SV, Chambert KD, Cheng W, Cloninger CR, Cohen D, Cormican P, Craddock N, Crespo-Facorro B, Crowley JJ, Curtis D, Davidson M, Davis KL, Degenhardt F, Del Favero J, DeLisi LE, Dikeos D, Dinan T, Djurovic S, Donohoe G, Drapeau E, Duan J, Dudbridge F, Eichhammer P, Eriksson J, Escott-Price V, Essioux L, Fanous AH, Farh KH, Farrell MS, Frank J, Franke L, Freedman R, Freimer NB, Friedman JI, Forstner AJ, Fromer M, Genovese G, Georgieva L, Gershon ES, Giegling I, Giusti-Rodríguez P, Godard S, Goldstein JI, Gratten J, de Haan L, Hamshere ML, Hansen M, Hansen T, Haroutunian V, Hartmann AM, Henskens FA, Herms S, Hirschhorn JN, Hoffmann P, Hofman A, Huang H, Ikeda M, Joa I, Kähler AK, Kahn RS, Kalaydjieva L, Karjalainen J, Kavanagh D, Keller MC, Kelly BJ, Kennedy JL, Kim Y, Knowles JA, Konte B, Laurent C, Lee P, Lee SH, Legge SE, Lerer B, Levy DL, Liang KY, Lieberman J, Lönnqvist J, Loughland CM, Magnusson PKE, Maher BS, Maier W, Mallet J, Mattheisen M, Mattingsdal M, McCarley RW, McDonald C, McIntosh AM, Meier S, Meijer CJ, Melle I, Mesholam-Gately RI, Metspalu A, Michie PT, Milani L, Milanova V, Mokrab Y, Morris DW, Müller-Myhsok B, Murphy KC, Murray RM, Myin-Germeys I, Nenadic I, Nertney DA, Nestadt G, Nicodemus KK, Nisenbaum L, Nordin A, O'Callaghan E, O'Dushlaine C, Oh SY, Olincy A, Olsen L, O'Neill FA, Van Os J, Pantelis C, Papadimitriou GN, Parkhomenko E, Pato MT, Paunio T; Psychosis Endophenotypes International Consortium, Perkins DO, Pers TH, Pietiläinen O, Pimm J, Pocklington AJ, Powell J, Price A, Pulver AE, Purcell SM, Quested D, Rasmussen HB, Reichenberg A, Reimers MA, Richards AL, Roffman JL, Roussos P, Ruderfer DM, Salomaa V, Sanders AR, Savitz A, Schall U, Schulze TG, Schwab SG, Scolnick EM, Scott RJ, Seidman LJ, Shi J, Silverman JM, Smoller JW, Söderman E, Spencer CCA, Stahl EA, Strengman E, Strohmaier J, Stroup TS, Suvisaari J, Svrakic DM, Szatkiewicz JP, Thirumalai S, Tooney PA, Veijola J, Visscher PM, Waddington J, Walsh D, Webb BT, Weiser M, Wildenauer DB, Williams NM, Williams S, Witt SH, Wolen AR, Wormley BK, Wray NR, Wu JQ, Zai CC, Adolfsson R, Andreassen OA, Blackwood DHR, Bramon E, Buxbaum JD, Cichon S, Collier DA, Corvin A, Daly MJ, Darvasi A, Domenici E, Esko T, Gejman PV, Gill M, Gurling H, Hultman CM, Iwata N, Jablensky AV, Jönsson EG, Kendler KS, Kirov G, Knight J, Levinson DF, Li QS, McCarroll SA, McQuillin A, Moran JL, Mowry BJ, Nöthen MM, Ophoff RA, Owen MJ, Palotie A, Pato CN, Petryshen TL, Posthuma D, Rietschel M, Riley BP, Rujescu D, Sklar P, St Clair D, Walters JTR, Werge T, Sullivan PF, O'Donovan MC, Scherer SW, Neale BM, Sebat J; CNV and Schizophrenia Working Groups of the Psychiatric Genomics Consortium.

Nat Genet. 2017 Jan;49(1):27-35. doi: 10.1038/ng.3725. Epub 2016 Nov 21.

PMID:
27869829
15.

Clk1 deficiency promotes neuroinflammation and subsequent dopaminergic cell death through regulation of microglial metabolic reprogramming.

Gu R, Zhang F, Chen G, Han C, Liu J, Ren Z, Zhu Y, Waddington JL, Zheng LT, Zhen X.

Brain Behav Immun. 2017 Feb;60:206-219. doi: 10.1016/j.bbi.2016.10.018. Epub 2016 Oct 18.

PMID:
27769915
16.

Gene × Environment Interactions in Schizophrenia: Evidence from Genetic Mouse Models.

Moran P, Stokes J, Marr J, Bock G, Desbonnet L, Waddington J, O'Tuathaigh C.

Neural Plast. 2016;2016:2173748. Epub 2016 Sep 20. Review.

17.

Immunological Mechanisms of Drug Hypersensitivity.

Meng X, Ariza A, Waddington J, Park K, Naisbitt D.

Curr Pharm Des. 2016;22(45):6734-6747. doi: 10.2174/1381612822666161003115103.

PMID:
27697025
18.

Mass Spectrometric and Functional Aspects of Drug-Protein Conjugation.

Tailor A, Waddington JC, Meng X, Park BK.

Chem Res Toxicol. 2016 Dec 19;29(12):1912-1935. Epub 2016 Sep 30. Review.

PMID:
27689879
19.

Epistatic and Independent Effects on Schizophrenia-Related Phenotypes Following Co-disruption of the Risk Factors Neuregulin-1 × DISC1.

O'Tuathaigh CM, Fumagalli F, Desbonnet L, Perez-Branguli F, Moloney G, Loftus S, O'Leary C, Petit E, Cox R, Tighe O, Clarke G, Lai D, Harvey RP, Cryan JF, Mitchell KJ, Dinan TG, Riva MA, Waddington JL.

Schizophr Bull. 2017 Jan;43(1):214-225. doi: 10.1093/schbul/sbw120. Epub 2016 Sep 9.

PMID:
27613806
20.

Amoxicillin and Clavulanate Form Chemically and Immunologically Distinct Multiple Haptenic Structures in Patients.

Meng X, Earnshaw CJ, Tailor A, Jenkins RE, Waddington JC, Whitaker P, French NS, Naisbitt DJ, Park BK.

Chem Res Toxicol. 2016 Oct 17;29(10):1762-1772. Epub 2016 Sep 21.

PMID:
27603302

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