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Items: 1 to 20 of 270

1.

In silico Pathway Activation Network Decomposition Analysis (iPANDA) as a method for biomarker development.

Ozerov IV, Lezhnina KV, Izumchenko E, Artemov AV, Medintsev S, Vanhaelen Q, Aliper A, Vijg J, Osipov AN, Labat I, West MD, Buzdin A, Cantor CR, Nikolsky Y, Borisov N, Irincheeva I, Khokhlovich E, Sidransky D, Camargo ML, Zhavoronkov A.

Nat Commun. 2016 Nov 16;7:13427. doi: 10.1038/ncomms13427.

PMID:
27848968
2.

Whole Chromosome Instability induces senescence and promotes SASP.

Andriani GA, Almeida VP, Faggioli F, Mauro M, Tsai WL, Santambrogio L, Maslov A, Gadina M, Campisi J, Vijg J, Montagna C.

Sci Rep. 2016 Oct 12;6:35218. doi: 10.1038/srep35218.

3.

Evidence for a limit to human lifespan.

Dong X, Milholland B, Vijg J.

Nature. 2016 Oct 5;538(7624):257-259. doi: 10.1038/nature19793. [Epub ahead of print]

4.

Do DNA Double-Strand Breaks Drive Aging?

White RR, Vijg J.

Mol Cell. 2016 Sep 1;63(5):729-38. doi: 10.1016/j.molcel.2016.08.004. Review.

PMID:
27588601
5.

Restricted diet delays accelerated ageing and genomic stress in DNA-repair-deficient mice.

Vermeij WP, Dollé ME, Reiling E, Jaarsma D, Payan-Gomez C, Bombardieri CR, Wu H, Roks AJ, Botter SM, van der Eerden BC, Youssef SA, Kuiper RV, Nagarajah B, van Oostrom CT, Brandt RM, Barnhoorn S, Imholz S, Pennings JL, de Bruin A, Gyenis Á, Pothof J, Vijg J, van Steeg H, Hoeijmakers JH.

Nature. 2016 Aug 24;537(7620):427-431. doi: 10.1038/nature19329. [Epub ahead of print]

PMID:
27556946
6.

Single-cell genome-wide bisulfite sequencing uncovers extensive heterogeneity in the mouse liver methylome.

Gravina S, Dong X, Yu B, Vijg J.

Genome Biol. 2016 Jul 5;17(1):150. doi: 10.1186/s13059-016-1011-3.

7.

Quantitative detection of low-abundance somatic structural variants in normal cells by high-throughput sequencing.

Quispe-Tintaya W, Gorbacheva T, Lee M, Makhortov S, Popov VN, Vijg J, Maslov AY.

Nat Methods. 2016 Jul;13(7):584-6. doi: 10.1038/nmeth.3893.

PMID:
27271197
8.

Deep biomarkers of human aging: Application of deep neural networks to biomarker development.

Putin E, Mamoshina P, Aliper A, Korzinkin M, Moskalev A, Kolosov A, Ostrovskiy A, Cantor C, Vijg J, Zhavoronkov A.

Aging (Albany NY). 2016 May;8(5):1021-33. doi: 10.18632/aging.100968.

9.

Systems-level analysis of human aging genes shed new light on mechanisms of aging.

Zhang Q, Nogales-Cadenas R, Lin JR, Zhang W, Cai Y, Vijg J, Zhang ZD.

Hum Mol Genet. 2016 Jul 15;25(14):2934-2947.

PMID:
27179790
10.

Sensitivity of primary fibroblasts in culture to atmospheric oxygen does not correlate with species lifespan.

Patrick A, Seluanov M, Hwang C, Tam J, Khan T, Morgenstern A, Wiener L, Vazquez JM, Zafar H, Wen R, Muratkalyeva M, Doerig K, Zagorulya M, Cole L, Catalano S, Lobo Ladd AA, Coppi AA, Coşkun Y, Tian X, Ablaeva J, Nevo E, Gladyshev VN, Zhang ZD, Vijg J, Seluanov A, Gorbunova V.

Aging (Albany NY). 2016 May;8(5):841-7. doi: 10.18632/aging.100958.

11.

Mechanisms and consequences of aneuploidy and chromosome instability in the aging brain.

Andriani GA, Vijg J, Montagna C.

Mech Ageing Dev. 2016 Mar 21. pii: S0047-6374(16)30028-8. doi: 10.1016/j.mad.2016.03.007. [Epub ahead of print]

PMID:
27013377
12.

The dark side of circulating nucleic acids.

Gravina S, Sedivy JM, Vijg J.

Aging Cell. 2016 Jun;15(3):398-9. doi: 10.1111/acel.12454. Review.

13.

DNA repair in species with extreme lifespan differences.

MacRae SL, Croken MM, Calder RB, Aliper A, Milholland B, White RR, Zhavoronkov A, Gladyshev VN, Seluanov A, Gorbunova V, Zhang ZD, Vijg J.

Aging (Albany NY). 2015 Dec;7(12):1171-84.

14.

Whole chromosome aneuploidy in the brain of Bub1bH/H and Ercc1-/Δ7 mice.

Andriani GA, Faggioli F, Baker D, Dollé ME, Sellers RS, Hébert JM, Van Steeg H, Hoeijmakers J, Vijg J, Montagna C.

Hum Mol Genet. 2016 Feb 15;25(4):755-65. doi: 10.1093/hmg/ddv612.

PMID:
26681803
15.

Comprehensive transcriptional landscape of aging mouse liver.

White RR, Milholland B, MacRae SL, Lin M, Zheng D, Vijg J.

BMC Genomics. 2015 Nov 5;16:899. doi: 10.1186/s12864-015-2061-8.

16.

The Essence of Aging.

Vijg J, Kennedy BK.

Gerontology. 2016;62(4):381-5. doi: 10.1159/000439348.

17.

Age-related somatic mutations in the cancer genome.

Milholland B, Auton A, Suh Y, Vijg J.

Oncotarget. 2015 Sep 22;6(28):24627-35. doi: 10.18632/oncotarget.5685.

18.

Development of a Targeted Multi-Disorder High-Throughput Sequencing Assay for the Effective Identification of Disease-Causing Variants.

Delio M, Patel K, Maslov A, Marion RW, McDonald TV, Cadoff EM, Golden A, Greally JM, Vijg J, Morrow B, Montagna C.

PLoS One. 2015 Jul 27;10(7):e0133742. doi: 10.1371/journal.pone.0133742.

19.

Genetic evidence for common pathways in human age-related diseases.

Johnson SC, Dong X, Vijg J, Suh Y.

Aging Cell. 2015 Oct;14(5):809-17. doi: 10.1111/acel.12362.

20.

High-throughput sequencing in mutation detection: A new generation of genotoxicity tests?

Maslov AY, Quispe-Tintaya W, Gorbacheva T, White RR, Vijg J.

Mutat Res. 2015 Jun;776:136-43. doi: 10.1016/j.mrfmmm.2015.03.014. Review.

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