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Effects of a dietary ketone ester on hippocampal glycolytic and tricarboxylic acid cycle intermediates and amino acids in a 3xTgAD mouse model of Alzheimer's disease.

Pawlosky RJ, Kemper MF, Kashiwaya Y, King MT, Mattson MP, Veech RL.

J Neurochem. 2017 Apr;141(2):195-207. doi: 10.1111/jnc.13958. Epub 2017 Mar 15.


A new way to produce hyperketonemia: use of ketone ester in a case of Alzheimer's disease.

Newport MT, VanItallie TB, Kashiwaya Y, King MT, Veech RL.

Alzheimers Dement. 2015 Jan;11(1):99-103. doi: 10.1016/j.jalz.2014.01.006. Epub 2014 Oct 7.


Ketone ester effects on metabolism and transcription.

Veech RL.

J Lipid Res. 2014 Oct;55(10):2004-6. doi: 10.1194/jlr.R046292. Epub 2014 Apr 8. Review.


Ketone esters increase brown fat in mice and overcome insulin resistance in other tissues in the rat.

Veech RL.

Ann N Y Acad Sci. 2013 Oct;1302:42-48. doi: 10.1111/nyas.12222. Epub 2013 Aug 2. Review.


A ketone ester diet exhibits anxiolytic and cognition-sparing properties, and lessens amyloid and tau pathologies in a mouse model of Alzheimer's disease.

Kashiwaya Y, Bergman C, Lee JH, Wan R, King MT, Mughal MR, Okun E, Clarke K, Mattson MP, Veech RL.

Neurobiol Aging. 2013 Jun;34(6):1530-9. doi: 10.1016/j.neurobiolaging.2012.11.023. Epub 2012 Dec 29.


A ketogenic diet increases brown adipose tissue mitochondrial proteins and UCP1 levels in mice.

Srivastava S, Baxa U, Niu G, Chen X, Veech RL.

IUBMB Life. 2013 Jan;65(1):58-66. doi: 10.1002/iub.1102. Epub 2012 Dec 10. Erratum in: IUBMB Life. 2014 Jul;66(7):519.


Microwave irradiation decreases ATP, increases free [Mg²⁺], and alters in vivo intracellular reactions in rat brain.

Srivastava S, Kashiwaya Y, Chen X, Geiger JD, Pawlosky R, Veech RL.

J Neurochem. 2012 Dec;123(5):668-75. doi: 10.1111/jnc.12026.


Kinetics, safety and tolerability of (R)-3-hydroxybutyl (R)-3-hydroxybutyrate in healthy adult subjects.

Clarke K, Tchabanenko K, Pawlosky R, Carter E, Todd King M, Musa-Veloso K, Ho M, Roberts A, Robertson J, Vanitallie TB, Veech RL.

Regul Toxicol Pharmacol. 2012 Aug;63(3):401-8. doi: 10.1016/j.yrtph.2012.04.008. Epub 2012 May 3.


Oral 28-day and developmental toxicity studies of (R)-3-hydroxybutyl (R)-3-hydroxybutyrate.

Clarke K, Tchabanenko K, Pawlosky R, Carter E, Knight NS, Murray AJ, Cochlin LE, King MT, Wong AW, Roberts A, Robertson J, Veech RL.

Regul Toxicol Pharmacol. 2012 Jul;63(2):196-208. doi: 10.1016/j.yrtph.2012.04.001. Epub 2012 Apr 11.


The unrecognized effects of the volume and composition of the resuscitation fluid used during the administration of blood products.

Robert Valeri C, Veech RL.

Transfus Apher Sci. 2012 Apr;46(2):121-3. doi: 10.1016/j.transci.2012.01.010. Epub 2012 Feb 22. Review.


Mitochondrial biogenesis and increased uncoupling protein 1 in brown adipose tissue of mice fed a ketone ester diet.

Srivastava S, Kashiwaya Y, King MT, Baxa U, Tam J, Niu G, Chen X, Clarke K, Veech RL.

FASEB J. 2012 Jun;26(6):2351-62. doi: 10.1096/fj.11-200410. Epub 2012 Feb 23.


The effect of pH and free Mg2+ on ATP linked enzymes and the calculation of Gibbs free energy of ATP hydrolysis.

Bergman C, Kashiwaya Y, Veech RL.

J Phys Chem B. 2010 Dec 16;114(49):16137-46. doi: 10.1021/jp105723r. Epub 2010 Sep 27.


A ketone ester diet increases brain malonyl-CoA and Uncoupling proteins 4 and 5 while decreasing food intake in the normal Wistar Rat.

Kashiwaya Y, Pawlosky R, Markis W, King MT, Bergman C, Srivastava S, Murray A, Clarke K, Veech RL.

J Biol Chem. 2010 Aug 20;285(34):25950-6. doi: 10.1074/jbc.M110.138198. Epub 2010 Jun 7.


Alterations in brain glucose utilization accompanying elevations in blood ethanol and acetate concentrations in the rat.

Pawlosky RJ, Kashiwaya Y, Srivastava S, King MT, Crutchfield C, Volkow N, Kunos G, Li TK, Veech RL.

Alcohol Clin Exp Res. 2010 Feb;34(2):375-81. doi: 10.1111/j.1530-0277.2009.01099.x. Epub 2009 Nov 24.


Severe adverse events associated with hemoglobin based oxygen carriers: role of resuscitative fluids and liquid preserved RBC.

Robert Valeri C, Ragno G, Veech RL.

Transfus Apher Sci. 2008 Dec;39(3):205-11. doi: 10.1016/j.transci.2008.09.008. Epub 2008 Oct 31. Review.


Ketoacids? Good medicine?

Cahill GF Jr, Veech RL.

Trans Am Clin Climatol Assoc. 2003;114:149-61; discussion 162-3. Review.


A humble hexose monophosphate pathway metabolite regulates short- and long-term control of lipogenesis.

Veech RL.

Proc Natl Acad Sci U S A. 2003 May 13;100(10):5578-80. Epub 2003 Apr 29. Review. No abstract available.

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