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Items: 19

1.

AMPK activation protects from neuronal dysfunction and vulnerability across nematode, cellular and mouse models of Huntington's disease.

Vázquez-Manrique RP, Farina F, Cambon K, Dolores Sequedo M, Parker AJ, Millán JM, Weiss A, Déglon N, Neri C.

Hum Mol Genet. 2016 Mar 15;25(6):1043-58. doi: 10.1093/hmg/ddv513.

2.

IP3 signalling regulates exogenous RNAi in Caenorhabditis elegans.

Nagy AI, Vázquez-Manrique RP, Lopez M, Christov CP, Sequedo MD, Herzog M, Herlihy AE, Bodak M, Gatsi R, Baylis HA.

EMBO Rep. 2015 Mar;16(3):341-50. doi: 10.15252/embr.201439585.

3.

Targeted next generation sequencing for molecular diagnosis of Usher syndrome.

Aparisi MJ, Aller E, Fuster-García C, García-García G, Rodrigo R, Vázquez-Manrique RP, Blanco-Kelly F, Ayuso C, Roux AF, Jaijo T, Millán JM.

Orphanet J Rare Dis. 2014 Nov 18;9:168. doi: 10.1186/s13023-014-0168-7.

4.

The Wnt receptor Ryk reduces neuronal and cell survival capacity by repressing FOXO activity during the early phases of mutant huntingtin pathogenicity.

Tourette C, Farina F, Vazquez-Manrique RP, Orfila AM, Voisin J, Hernandez S, Offner N, Parker JA, Menet S, Kim J, Lyu J, Choi SH, Cormier K, Edgerly CK, Bordiuk OL, Smith K, Louise A, Halford M, Stacker S, Vert JP, Ferrante RJ, Lu W, Neri C.

PLoS Biol. 2014 Jun 24;12(6):e1001895. doi: 10.1371/journal.pbio.1001895.

5.

Integration of β-catenin, sirtuin, and FOXO signaling protects from mutant huntingtin toxicity.

Parker JA, Vazquez-Manrique RP, Tourette C, Farina F, Offner N, Mukhopadhyay A, Orfila AM, Darbois A, Menet S, Tissenbaum HA, Neri C.

J Neurosci. 2012 Sep 5;32(36):12630-40. doi: 10.1523/JNEUROSCI.0277-12.2012.

6.

Delaying aging and the aging-associated decline in protein homeostasis by inhibition of tryptophan degradation.

van der Goot AT, Zhu W, Vázquez-Manrique RP, Seinstra RI, Dettmer K, Michels H, Farina F, Krijnen J, Melki R, Buijsman RC, Ruiz Silva M, Thijssen KL, Kema IP, Neri C, Oefner PJ, Nollen EA.

Proc Natl Acad Sci U S A. 2012 Sep 11;109(37):14912-7. doi: 10.1073/pnas.1203083109.

7.

Large-scale functional RNAi screen in C. elegans identifies genes that regulate the dysfunction of mutant polyglutamine neurons.

Lejeune FX, Mesrob L, Parmentier F, Bicep C, Vazquez-Manrique RP, Parker JA, Vert JP, Tourette C, Neri C.

BMC Genomics. 2012 Mar 13;13:91. doi: 10.1186/1471-2164-13-91.

8.

Genetic analysis of IP3 and calcium signalling pathways in C. elegans.

Baylis HA, Vázquez-Manrique RP.

Biochim Biophys Acta. 2012 Aug;1820(8):1253-68. doi: 10.1016/j.bbagen.2011.11.009. Review.

PMID:
22146231
9.

Absence of effects of Sir2 overexpression on lifespan in C. elegans and Drosophila.

Burnett C, Valentini S, Cabreiro F, Goss M, Somogyvári M, Piper MD, Hoddinott M, Sutphin GL, Leko V, McElwee JJ, Vazquez-Manrique RP, Orfila AM, Ackerman D, Au C, Vinti G, Riesen M, Howard K, Neri C, Bedalov A, Kaeberlein M, Soti C, Partridge L, Gems D.

Nature. 2011 Sep 21;477(7365):482-5. doi: 10.1038/nature10296.

10.

Reverse genetic strategies in Caenorhabditis elegans: towards controlled manipulation of the genome.

Baylis HA, Vázquez-Manrique RP.

ScientificWorldJournal. 2011 Jul 7;11:1394-410. doi: 10.1100/tsw.2011.126. Review.

11.

Disruption of the ATP-binding cassette B7 (ABTM-1/ABCB7) induces oxidative stress and premature cell death in Caenorhabditis elegans.

González-Cabo P, Bolinches-Amorós A, Cabello J, Ros S, Moreno S, Baylis HA, Palau F, Vázquez-Manrique RP.

J Biol Chem. 2011 Jun 17;286(24):21304-14. doi: 10.1074/jbc.M110.211201.

12.

Improved gene targeting in C. elegans using counter-selection and Flp-mediated marker excision.

Vázquez-Manrique RP, Legg JC, Olofsson B, Ly S, Baylis HA.

Genomics. 2010 Jan;95(1):37-46. doi: 10.1016/j.ygeno.2009.09.001.

13.

Inositol 1,4,5-trisphosphate signalling regulates the avoidance response to nose touch in Caenorhabditis elegans.

Walker DS, Vázquez-Manrique RP, Gower NJ, Gregory E, Schafer WR, Baylis HA.

PLoS Genet. 2009 Sep;5(9):e1000636. doi: 10.1371/journal.pgen.1000636.

14.

TRPM channels are required for rhythmicity in the ultradian defecation rhythm of C. elegans.

Kwan CS, Vázquez-Manrique RP, Ly S, Goyal K, Baylis HA.

BMC Physiol. 2008 May 21;8:11. doi: 10.1186/1472-6793-8-11.

15.

Phospholipase C-epsilon regulates epidermal morphogenesis in Caenorhabditis elegans.

Vázquez-Manrique RP, Nagy AI, Legg JC, Bales OA, Ly S, Baylis HA.

PLoS Genet. 2008 Mar 28;4(3):e1000043. doi: 10.1371/journal.pgen.1000043.

16.

The frataxin-encoding operon of Caenorhabditis elegans shows complex structure and regulation.

Vázquez-Manrique RP, González-Cabo P, Ortiz-Martín I, Ros S, Baylis HA, Palau F.

Genomics. 2007 Mar;89(3):392-401.

17.
18.

Frataxin interacts functionally with mitochondrial electron transport chain proteins.

González-Cabo P, Vázquez-Manrique RP, García-Gimeno MA, Sanz P, Palau F.

Hum Mol Genet. 2005 Aug 1;14(15):2091-8.

19.

Evolution of gypsy endogenous retrovirus in the Drosophila obscura species group.

Vázquez-Manrique RP, Hernández M, Martínez-Sebastián MJ, de Frutos R.

Mol Biol Evol. 2000 Aug;17(8):1185-93.

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