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Items: 1 to 20 of 28

1.

Intestinal virome changes precede autoimmunity in type I diabetes-susceptible children.

Zhao G, Vatanen T, Droit L, Park A, Kostic AD, Poon TW, Vlamakis H, Siljander H, Härkönen T, Hämäläinen AM, Peet A, Tillmann V, Ilonen J, Wang D, Knip M, Xavier RJ, Virgin HW.

Proc Natl Acad Sci U S A. 2017 Jul 10. pii: 201706359. doi: 10.1073/pnas.1706359114. [Epub ahead of print]

PMID:
28696303
2.

High-throughput automated microfluidic sample preparation for accurate microbial genomics.

Kim S, De Jonghe J, Kulesa AB, Feldman D, Vatanen T, Bhattacharyya RP, Berdy B, Gomez J, Nolan J, Epstein S, Blainey PC.

Nat Commun. 2017 Jan 27;8:13919. doi: 10.1038/ncomms13919.

3.

The effect of host genetics on the gut microbiome.

Bonder MJ, Kurilshikov A, Tigchelaar EF, Mujagic Z, Imhann F, Vila AV, Deelen P, Vatanen T, Schirmer M, Smeekens SP, Zhernakova DV, Jankipersadsing SA, Jaeger M, Oosting M, Cenit MC, Masclee AA, Swertz MA, Li Y, Kumar V, Joosten L, Harmsen H, Weersma RK, Franke L, Hofker MH, Xavier RJ, Jonkers D, Netea MG, Wijmenga C, Fu J, Zhernakova A.

Nat Genet. 2016 Nov;48(11):1407-1412. doi: 10.1038/ng.3663. Epub 2016 Oct 3.

PMID:
27694959
4.

Increased Intestinal Microbial Diversity Following Fecal Microbiota Transplant for Active Crohn's Disease.

Vaughn BP, Vatanen T, Allegretti JR, Bai A, Xavier RJ, Korzenik J, Gevers D, Ting A, Robson SC, Moss AC.

Inflamm Bowel Dis. 2016 Sep;22(9):2182-90. doi: 10.1097/MIB.0000000000000893.

PMID:
27542133
5.

Dysbiosis, inflammation, and response to treatment: a longitudinal study of pediatric subjects with newly diagnosed inflammatory bowel disease.

Shaw KA, Bertha M, Hofmekler T, Chopra P, Vatanen T, Srivatsa A, Prince J, Kumar A, Sauer C, Zwick ME, Satten GA, Kostic AD, Mulle JG, Xavier RJ, Kugathasan S.

Genome Med. 2016 Jul 13;8(1):75. doi: 10.1186/s13073-016-0331-y.

6.

Natural history of the infant gut microbiome and impact of antibiotic treatment on bacterial strain diversity and stability.

Yassour M, Vatanen T, Siljander H, Hämäläinen AM, Härkönen T, Ryhänen SJ, Franzosa EA, Vlamakis H, Huttenhower C, Gevers D, Lander ES, Knip M; DIABIMMUNE Study Group, Xavier RJ.

Sci Transl Med. 2016 Jun 15;8(343):343ra81. doi: 10.1126/scitranslmed.aad0917.

7.

Variation in Microbiome LPS Immunogenicity Contributes to Autoimmunity in Humans.

Vatanen T, Kostic AD, d'Hennezel E, Siljander H, Franzosa EA, Yassour M, Kolde R, Vlamakis H, Arthur TD, Hämäläinen AM, Peet A, Tillmann V, Uibo R, Mokurov S, Dorshakova N, Ilonen J, Virtanen SM, Szabo SJ, Porter JA, Lähdesmäki H, Huttenhower C, Gevers D, Cullen TW, Knip M; DIABIMMUNE Study Group, Xavier RJ.

Cell. 2016 Jun 2;165(6):1551. doi: 10.1016/j.cell.2016.05.056. No abstract available.

8.

Variation in Microbiome LPS Immunogenicity Contributes to Autoimmunity in Humans.

Vatanen T, Kostic AD, d'Hennezel E, Siljander H, Franzosa EA, Yassour M, Kolde R, Vlamakis H, Arthur TD, Hämäläinen AM, Peet A, Tillmann V, Uibo R, Mokurov S, Dorshakova N, Ilonen J, Virtanen SM, Szabo SJ, Porter JA, Lähdesmäki H, Huttenhower C, Gevers D, Cullen TW, Knip M; DIABIMMUNE Study Group, Xavier RJ.

Cell. 2016 May 5;165(4):842-53. doi: 10.1016/j.cell.2016.04.007. Epub 2016 Apr 28. Erratum in: Cell. 2016 Jun 2;165(6):1551.

9.

Population-based metagenomics analysis reveals markers for gut microbiome composition and diversity.

Zhernakova A, Kurilshikov A, Bonder MJ, Tigchelaar EF, Schirmer M, Vatanen T, Mujagic Z, Vila AV, Falony G, Vieira-Silva S, Wang J, Imhann F, Brandsma E, Jankipersadsing SA, Joossens M, Cenit MC, Deelen P, Swertz MA; LifeLines cohort study, Weersma RK, Feskens EJ, Netea MG, Gevers D, Jonkers D, Franke L, Aulchenko YS, Huttenhower C, Raes J, Hofker MH, Xavier RJ, Wijmenga C, Fu J.

Science. 2016 Apr 29;352(6285):565-9. doi: 10.1126/science.aad3369. Epub 2016 Apr 28.

10.

The influence of a short-term gluten-free diet on the human gut microbiome.

Bonder MJ, Tigchelaar EF, Cai X, Trynka G, Cenit MC, Hrdlickova B, Zhong H, Vatanen T, Gevers D, Wijmenga C, Wang Y, Zhernakova A.

Genome Med. 2016 Apr 21;8(1):45. doi: 10.1186/s13073-016-0295-y.

11.

Urinary adiponectin is an independent predictor of progression to end-stage renal disease in patients with type 1 diabetes and diabetic nephropathy.

Panduru NM, Saraheimo M, Forsblom C, Thorn LM, Gordin D, Wadén J, Tolonen N, Bierhaus A, Humpert PM, Groop PH; FinnDiane Study Group.

Diabetes Care. 2015 May;38(5):883-90. doi: 10.2337/dc14-2276. Epub 2015 Feb 26.

PMID:
25720601
12.

The dynamics of the human infant gut microbiome in development and in progression toward type 1 diabetes.

Kostic AD, Gevers D, Siljander H, Vatanen T, Hyötyläinen T, Hämäläinen AM, Peet A, Tillmann V, Pöhö P, Mattila I, Lähdesmäki H, Franzosa EA, Vaarala O, de Goffau M, Harmsen H, Ilonen J, Virtanen SM, Clish CB, Orešič M, Huttenhower C, Knip M; DIABIMMUNE Study Group, Xavier RJ.

Cell Host Microbe. 2015 Feb 11;17(2):260-73. doi: 10.1016/j.chom.2015.01.001. Epub 2015 Feb 5.

13.

Incidence of stroke according to presence of diabetic nephropathy and severe diabetic retinopathy in patients with type 1 diabetes.

Hägg S, Thorn LM, Putaala J, Liebkind R, Harjutsalo V, Forsblom CM, Gordin D, Tatlisumak T, Groop PH; FinnDiane Study Group.

Diabetes Care. 2013 Dec;36(12):4140-6. doi: 10.2337/dc13-0669. Epub 2013 Oct 7.

14.

Chromosome 2q31.1 associates with ESRD in women with type 1 diabetes.

Sandholm N, McKnight AJ, Salem RM, Brennan EP, Forsblom C, Harjutsalo V, Mäkinen VP, McKay GJ, Sadlier DM, Williams WW, Martin F, Panduru NM, Tarnow L, Tuomilehto J, Tryggvason K, Zerbini G, Comeau ME, Langefeld CD; FIND Consortium, Godson C, Hirschhorn JN, Maxwell AP, Florez JC, Groop PH; FinnDiane Study Group and the GENIE Consortium.

J Am Soc Nephrol. 2013 Oct;24(10):1537-43. doi: 10.1681/ASN.2012111122. Epub 2013 Sep 12.

15.

Patients with Type 1 diabetes consuming alcoholic spirits have an increased risk of microvascular complications.

Harjutsalo V, Feodoroff M, Forsblom C, Groop PH; FinnDiane Study Group.

Diabet Med. 2014 Feb;31(2):156-64. doi: 10.1111/dme.12307. Epub 2013 Sep 14.

PMID:
23952587
16.

Associations and interactions between lipid profiles, retinopathy and nephropathy in patients with type 1 diabetes: the FinnDiane Study.

Tolonen N, Hietala K, Forsblom C, Harjutsalo V, Mäkinen VP, Kytö J, Summanen PA, Thorn LM, Wadén J, Gordin D, Taskinen MR, Groop PH; FinnDiane Study Group.

J Intern Med. 2013 Nov;274(5):469-79. doi: 10.1111/joim.12111. Epub 2013 Aug 1.

17.

Urinary liver-type fatty acid-binding protein and progression of diabetic nephropathy in type 1 diabetes.

Panduru NM, Forsblom C, Saraheimo M, Thorn L, Bierhaus A, Humpert PM, Groop PH; FinnDiane Study Group.

Diabetes Care. 2013 Jul;36(7):2077-83. doi: 10.2337/dc12-1868. Epub 2013 Feb 1.

18.

The absence of macrophage Nrf2 promotes early atherogenesis.

Ruotsalainen AK, Inkala M, Partanen ME, Lappalainen JP, Kansanen E, Mäkinen PI, Heinonen SE, Laitinen HM, Heikkilä J, Vatanen T, Hörkkö S, Yamamoto M, Ylä-Herttuala S, Jauhiainen M, Levonen AL.

Cardiovasc Res. 2013 Apr 1;98(1):107-15. doi: 10.1093/cvr/cvt008. Epub 2013 Jan 22.

PMID:
23341579
19.

Purchase of antidepressant agents by patients with type 1 diabetes is associated with increased mortality rates in women but not in men.

Ahola AJ, Harjutsalo V, Saraheimo M, Forsblom C, Groop PH; FinnDiane Study Group.

Diabetologia. 2012 Jan;55(1):73-9. doi: 10.1007/s00125-011-2347-6. Epub 2011 Oct 28.

PMID:
22033620
20.

Novel susceptibility locus at 22q11 for diabetic nephropathy in type 1 diabetes.

Wessman M, Forsblom C, Kaunisto MA, Söderlund J, Ilonen J, Sallinen R, Hiekkalinna T, Parkkonen M, Maxwell AP, Tarnow L, Parving HH, Hadjadj S, Marre M, Peltonen L, Groop PH; FinnDiane Study Group.

PLoS One. 2011;6(9):e24053. doi: 10.1371/journal.pone.0024053. Epub 2011 Sep 1.

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