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Items: 18

1.

Analysis of Plasminogen Genetic Variants in Multiple Sclerosis Patients.

Sadovnick AD, Traboulsee AL, Bernales CQ, Ross JP, Forwell AL, Yee IM, Guillot-Noel L, Fontaine B, Cournu-Rebeix I, Alcina A, Fedetz M, Izquierdo G, Matesanz F, Hilven K, Dubois B, Goris A, Astobiza I, Alloza I, Antigüedad A, Vandenbroeck K, Akkad DA, Aktas O, Blaschke P, Buttmann M, Chan A, Epplen JT, Gerdes LA, Kroner A, Kubisch C, Kümpfel T, Lohse P, Rieckmann P, Zettl UK, Zipp F, Bertram L, Lill CM, Fernandez O, Urbaneja P, Leyva L, Alvarez-Cermeño JC, Arroyo R, Garagorri AM, García-Martínez A, Villar LM, Urcelay E, Malhotra S, Montalban X, Comabella M, Berger T, Fazekas F, Reindl M, Schmied MC, Zimprich A, Vilariño-Güell C.

G3 (Bethesda). 2016 Jul 7;6(7):2073-9. doi: 10.1534/g3.116.030841.

2.

Pharmacogenomic study in patients with multiple sclerosis: Responders and nonresponders to IFN-β.

Bustamante MF, Morcillo-Suárez C, Malhotra S, Rio J, Leyva L, Fernández O, Zettl UK, Killestein J, Brassat D, García-Merino JA, Sánchez AJ, Urcelay E, Alvarez-Lafuente R, Villar LM, Alvarez-Cermeño JC, Farré X, Lechner-Scott J, Vandenbroeck K, Rodríguez-Antigüedad A, Drulovic JS, Martinelli Boneschi F, Chan A, Oksenberg J, Navarro A, Montalban X, Comabella M.

Neurol Neuroimmunol Neuroinflamm. 2015 Sep 24;2(5):e154. doi: 10.1212/NXI.0000000000000154. eCollection 2015 Oct.

3.

Autophagic marker MAP1LC3B expression levels are associated with carotid atherosclerosis symptomatology.

Swaminathan B, Goikuria H, Vega R, Rodríguez-Antigüedad A, López Medina A, Freijo Mdel M, Vandenbroeck K, Alloza I.

PLoS One. 2014 Dec 12;9(12):e115176. doi: 10.1371/journal.pone.0115176. eCollection 2014.

4.

Human endogenous retrovirus HERV-Fc1 association with multiple sclerosis susceptibility: a meta-analysis.

de la Hera B, Varadé J, García-Montojo M, Alcina A, Fedetz M, Alloza I, Astobiza I, Leyva L, Fernández O, Izquierdo G, Antigüedad A, Arroyo R, Álvarez-Lafuente R, Vandenbroeck K, Matesanz F, Urcelay E.

PLoS One. 2014 Mar 3;9(3):e90182. doi: 10.1371/journal.pone.0090182. eCollection 2014.

5.

A trifluoromethyl analogue of celecoxib exerts beneficial effects in neuroinflammation.

Di Penta A, Chiba A, Alloza I, Wyssenbach A, Yamamura T, Villoslada P, Miyake S, Vandenbroeck K.

PLoS One. 2013 Dec 11;8(12):e83119. doi: 10.1371/journal.pone.0083119. eCollection 2013.

6.

MANBA, CXCR5, SOX8, RPS6KB1 and ZBTB46 are genetic risk loci for multiple sclerosis.

International Multiple Sclerosis Genetics Consortium., Lill CM, Schjeide BM, Graetz C, Ban M, Alcina A, Ortiz MA, Pérez J, Damotte V, Booth D, Lopez de Lapuente A, Broer L, Schilling M, Akkad DA, Aktas O, Alloza I, Antigüedad A, Arroyo R, Blaschke P, Buttmann M, Chan A, Compston A, Cournu-Rebeix I, Dörner T, Epplen JT, Fernández Ó, Gerdes LA, Guillot-Noël L, Hartung HP, Hoffjan S, Izquierdo G, Kemppinen A, Kroner A, Kubisch C, Kümpfel T, Li SC, Lindenberger U, Lohse P, Lubetzki C, Luessi F, Malhotra S, Mescheriakova J, Montalban X, Papeix C, Paredes LF, Rieckmann P, Steinhagen-Thiessen E, Winkelmann A, Zettl UK, Hintzen R, Vandenbroeck K, Stewart G, Fontaine B, Comabella M, Urcelay E, Matesanz F, Sawcer S, Bertram L, Zipp F.

Brain. 2013 Jun;136(Pt 6):1778-82. doi: 10.1093/brain/awt101.

7.

Fine mapping and functional analysis of the multiple sclerosis risk gene CD6.

Swaminathan B, Cuapio A, Alloza I, Matesanz F, Alcina A, García-Barcina M, Fedetz M, Fernández O, Lucas M, Orpez T, Pinto-Medel MJ, Otaegui D, Olascoaga J, Urcelay E, Ortiz MA, Arroyo R, Oksenberg JR, Antigüedad A, Tolosa E, Vandenbroeck K.

PLoS One. 2013 Apr 24;8(4):e62376. doi: 10.1371/journal.pone.0062376. Print 2013.

8.

Oxidative stress and proinflammatory cytokines contribute to demyelination and axonal damage in a cerebellar culture model of neuroinflammation.

di Penta A, Moreno B, Reix S, Fernandez-Diez B, Villanueva M, Errea O, Escala N, Vandenbroeck K, Comella JX, Villoslada P.

PLoS One. 2013;8(2):e54722. doi: 10.1371/journal.pone.0054722. Epub 2013 Feb 19.

9.

Identification of a functional variant in the KIF5A-CYP27B1-METTL1-FAM119B locus associated with multiple sclerosis.

Alcina A, Fedetz M, Fernández O, Saiz A, Izquierdo G, Lucas M, Leyva L, García-León JA, Abad-Grau Mdel M, Alloza I, Antigüedad A, Garcia-Barcina MJ, Vandenbroeck K, Varadé J, de la Hera B, Arroyo R, Comabella M, Montalban X, Petit-Marty N, Navarro A, Otaegui D, Olascoaga J, Blanco Y, Urcelay E, Matesanz F.

J Med Genet. 2013 Jan;50(1):25-33. doi: 10.1136/jmedgenet-2012-101085. Epub 2012 Nov 17.

10.

A 4-trifluoromethyl analogue of celecoxib inhibits arthritis by suppressing innate immune cell activation.

Chiba A, Mizuno M, Tomi C, Tajima R, Alloza I, di Penta A, Yamamura T, Vandenbroeck K, Miyake S.

Arthritis Res Ther. 2012 Jan 17;14(1):R9. doi: 10.1186/ar3683.

11.

Cytokine gene polymorphisms and human autoimmune disease in the era of genome-wide association studies.

Vandenbroeck K.

J Interferon Cytokine Res. 2012 Apr;32(4):139-51. doi: 10.1089/jir.2011.0103. Epub 2011 Dec 22. Review.

12.

High affinity binding of hydrophobic and autoantigenic regions of proinsulin to the 70 kDa chaperone DnaK.

Burkart V, Siegenthaler RK, Blasius E, Vandenbroeck K, Alloza I, Fingberg W, Schloot NC, Christen P, Kolb H.

BMC Biochem. 2010 Nov 8;11:44. doi: 10.1186/1471-2091-11-44.

13.

The endoplasmic reticulum protein folding factory and its chaperones: new targets for drug discovery?

McLaughlin M, Vandenbroeck K.

Br J Pharmacol. 2011 Jan;162(2):328-45. doi: 10.1111/j.1476-5381.2010.01064.x. Review.

14.

Inhibition of secretion of interleukin (IL)-12/IL-23 family cytokines by 4-trifluoromethyl-celecoxib is coupled to degradation via the endoplasmic reticulum stress protein HERP.

McLaughlin M, Alloza I, Quoc HP, Scott CJ, Hirabayashi Y, Vandenbroeck K.

J Biol Chem. 2010 Mar 5;285(10):6960-9. doi: 10.1074/jbc.M109.056614. Epub 2010 Jan 6.

15.

Genetic polymorphisms, their allele combinations and IFN-beta treatment response in Irish multiple sclerosis patients.

O'Doherty C, Favorov A, Heggarty S, Graham C, Favorova O, Ochs M, Hawkins S, Hutchinson M, O'Rourke K, Vandenbroeck K.

Pharmacogenomics. 2009 Jul;10(7):1177-86. doi: 10.2217/pgs.09.41.

16.

Pharmacogenomic studies of the anticancer and immunosuppressive thiopurines mercaptopurine and azathioprine.

Hawwa AF, Millership JS, Collier PS, Vandenbroeck K, McCarthy A, Dempsey S, Cairns C, Collins J, Rodgers C, McElnay JC.

Br J Clin Pharmacol. 2008 Oct;66(4):517-28. doi: 10.1111/j.1365-2125.2008.03248.x. Epub 2008 Jun 28.

17.

Irreversible inhibition of the bacterial cysteine protease-transpeptidase sortase (SrtA) by substrate-derived affinity labels.

Scott CJ, McDowell A, Martin SL, Lynas JF, Vandenbroeck K, Walker B.

Biochem J. 2002 Sep 15;366(Pt 3):953-8.

18.

Sequence of the porcine interferon-gamma (IFN-gamma) gene.

Dijkmans R, Vandenbroeck K, Beuken E, Billiau A.

Nucleic Acids Res. 1990 Jul 25;18(14):4259. No abstract available. Erratum in: Nucleic Acids Res 1990 Oct 11;18(19):5943. Roger D [corrected to Dijkmans R]; Koen V [corrected to Vandenbroeck K]; Erik B [corrected to Beuken E]; Alfons B [corrected to Billiau A].

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