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Items: 1 to 20 of 448

1.

Ubiquitin-Mediated Regulation of RIPK1 Kinase Activity Independent of IKK and MK2.

Annibaldi A, Wicky John S, Vanden Berghe T, Swatek KN, Ruan J, Liccardi G, Bianchi K, Elliott PR, Choi SM, Van Coillie S, Bertin J, Wu H, Komander D, Vandenabeele P, Silke J, Meier P.

Mol Cell. 2018 Feb 15;69(4):566-580.e5. doi: 10.1016/j.molcel.2018.01.027.

PMID:
29452637
2.

Tozasertib analogues as inhibitors of necroptotic cell death.

Hofmans S, Devisscher L, Martens S, Van Rompaey D, Goossens K, Divert T, Nerinckx W, Takahashi N, De Winter H, Van der Veken P, Goossens V, Vandenabeele P, Augustyns K.

J Med Chem. 2018 Feb 13. doi: 10.1021/acs.jmedchem.7b01449. [Epub ahead of print]

PMID:
29437386
3.

RIPK4 activity in keratinocytes is controlled by the SCFβ-TrCP ubiquitin ligase to maintain cortical actin organization.

Tanghe G, Urwyler-Rösselet C, De Groote P, Dejardin E, De Bock PJ, Gevaert K, Vandenabeele P, Declercq W.

Cell Mol Life Sci. 2018 Feb 12. doi: 10.1007/s00018-018-2763-6. [Epub ahead of print]

PMID:
29435596
4.

RIPK1-dependent cell death: a novel target of the Aurora kinase inhibitor Tozasertib (VX-680).

Martens S, Goossens V, Devisscher L, Hofmans S, Claeys P, Vuylsteke M, Takahashi N, Augustyns K, Vandenabeele P.

Cell Death Dis. 2018 Feb 12;9(2):211. doi: 10.1038/s41419-017-0245-7.

PMID:
29434255
5.

Noninvasive whole-body imaging of phosphatidylethanolamine as a cell death marker using 99mTc-duramycin during TNF-induced SIRS.

Delvaeye T, Wyffels L, Deleye S, Lemeire K, Gonçalves A, Decrock E, Staelens S, Leybaert L, Vandenabeele P, Krysko D.

J Nucl Med. 2018 Feb 1. pii: jnumed.117.205815. doi: 10.2967/jnumed.117.205815. [Epub ahead of print]

PMID:
29419481
6.

Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018.

Galluzzi L, Vitale I, Aaronson SA, Abrams JM, Adam D, Agostinis P, Alnemri ES, Altucci L, Amelio I, Andrews DW, Annicchiarico-Petruzzelli M, Antonov AV, Arama E, Baehrecke EH, Barlev NA, Bazan NG, Bernassola F, Bertrand MJM, Bianchi K, Blagosklonny MV, Blomgren K, Borner C, Boya P, Brenner C, Campanella M, Candi E, Carmona-Gutierrez D, Cecconi F, Chan FK, Chandel NS, Cheng EH, Chipuk JE, Cidlowski JA, Ciechanover A, Cohen GM, Conrad M, Cubillos-Ruiz JR, Czabotar PE, D'Angiolella V, Dawson TM, Dawson VL, De Laurenzi V, De Maria R, Debatin KM, DeBerardinis RJ, Deshmukh M, Di Daniele N, Di Virgilio F, Dixit VM, Dixon SJ, Duckett CS, Dynlacht BD, El-Deiry WS, Elrod JW, Fimia GM, Fulda S, García-Sáez AJ, Garg AD, Garrido C, Gavathiotis E, Golstein P, Gottlieb E, Green DR, Greene LA, Gronemeyer H, Gross A, Hajnoczky G, Hardwick JM, Harris IS, Hengartner MO, Hetz C, Ichijo H, Jäättelä M, Joseph B, Jost PJ, Juin PP, Kaiser WJ, Karin M, Kaufmann T, Kepp O, Kimchi A, Kitsis RN, Klionsky DJ, Knight RA, Kumar S, Lee SW, Lemasters JJ, Levine B, Linkermann A, Lipton SA, Lockshin RA, López-Otín C, Lowe SW, Luedde T, Lugli E, MacFarlane M, Madeo F, Malewicz M, Malorni W, Manic G, Marine JC, Martin SJ, Martinou JC, Medema JP, Mehlen P, Meier P, Melino S, Miao EA, Molkentin JD, Moll UM, Muñoz-Pinedo C, Nagata S, Nuñez G, Oberst A, Oren M, Overholtzer M, Pagano M, Panaretakis T, Pasparakis M, Penninger JM, Pereira DM, Pervaiz S, Peter ME, Piacentini M, Pinton P, Prehn JHM, Puthalakath H, Rabinovich GA, Rehm M, Rizzuto R, Rodrigues CMP, Rubinsztein DC, Rudel T, Ryan KM, Sayan E, Scorrano L, Shao F, Shi Y, Silke J, Simon HU, Sistigu A, Stockwell BR, Strasser A, Szabadkai G, Tait SWG, Tang D, Tavernarakis N, Thorburn A, Tsujimoto Y, Turk B, Vanden Berghe T, Vandenabeele P, Vander Heiden MG, Villunger A, Virgin HW, Vousden KH, Vucic D, Wagner EF, Walczak H, Wallach D, Wang Y, Wells JA, Wood W, Yuan J, Zakeri Z, Zhivotovsky B, Zitvogel L, Melino G, Kroemer G.

Cell Death Differ. 2018 Jan 23. doi: 10.1038/s41418-017-0012-4. [Epub ahead of print] Review.

PMID:
29362479
7.

Nanoscopic X-ray fluorescence imaging and quantification of intracellular key-elements in cryofrozen Friedreich's ataxia fibroblasts.

De Samber B, Meul E, Laforce B, De Paepe B, Smet J, De Bruyne M, De Rycke R, Bohic S, Cloetens P, Van Coster R, Vandenabeele P, Vanden Berghe T.

PLoS One. 2018 Jan 17;13(1):e0190495. doi: 10.1371/journal.pone.0190495. eCollection 2018.

8.

Keratinocyte-specific ablation of RIPK4 allows epidermal cornification but impairs skin barrier formation.

Urwyler-Rösselet C, Tanghe G, Leurs K, Gilbert B, De Rycke R, De Bruyne M, Lippens S, Bartunkova S, De Groote P, Niessen C, Haftek M, Vandenabeele P, Declercq W.

J Invest Dermatol. 2018 Jan 6. pii: S0022-202X(18)30006-X. doi: 10.1016/j.jid.2017.12.031. [Epub ahead of print]

PMID:
29317263
9.

Necroptotic cell death in anti-cancer therapy.

Krysko O, Aaes TL, Kagan VE, D'Herde K, Bachert C, Leybaert L, Vandenabeele P, Krysko DV.

Immunol Rev. 2017 Nov;280(1):207-219. doi: 10.1111/imr.12583. Review.

PMID:
29027225
10.

6E11, a highly selective inhibitor of Receptor-Interacting Protein Kinase 1, protects cells against cold hypoxia-reoxygenation injury.

Delehouzé C, Leverrier-Penna S, Le Cann F, Comte A, Jacquard-Fevai M, Delalande O, Desban N, Baratte B, Gallais I, Faurez F, Bonnet MC, Hauteville M, Goekjian PG, Thuillier R, Favreau F, Vandenabeele P, Hauet T, Dimanche-Boitrel MT, Bach S.

Sci Rep. 2017 Oct 10;7(1):12931. doi: 10.1038/s41598-017-12788-4.

11.

How do we fit ferroptosis in the family of regulated cell death?

Fearnhead HO, Vandenabeele P, Vanden Berghe T.

Cell Death Differ. 2017 Dec;24(12):1991-1998. doi: 10.1038/cdd.2017.149. Epub 2017 Oct 6. Review.

PMID:
28984871
12.

Sorafenib inhibits therapeutic induction of necroptosis in acute leukemia cells.

Feldmann F, Schenk B, Martens S, Vandenabeele P, Fulda S.

Oncotarget. 2017 Aug 4;8(40):68208-68220. doi: 10.18632/oncotarget.19919. eCollection 2017 Sep 15.

13.

Heme Oxygenase Activity and Heme Binding in a Neonatal Mouse Model.

Kourula S, Ang J, Zhao H, Kalish F, Vandenabeele P, Sylvester KG, Wong RJ, Stevenson DK.

Neonatology. 2017;112(4):376-383. doi: 10.1159/000479493. Epub 2017 Sep 20.

PMID:
28926834
14.

MK2 phosphorylation of RIPK1 regulates TNF-mediated cell death.

Dondelinger Y, Delanghe T, Rojas-Rivera D, Priem D, Delvaeye T, Bruggeman I, Van Herreweghe F, Vandenabeele P, Bertrand MJM.

Nat Cell Biol. 2017 Oct;19(10):1237-1247. doi: 10.1038/ncb3608. Epub 2017 Sep 18.

PMID:
28920952
15.

RIPK1 protects hepatocytes from death in Fas-induced hepatitis.

Filliol A, Farooq M, Piquet-Pellorce C, Genet V, Dimanche-Boitrel MT, Vandenabeele P, Bertrand MJM, Samson M, Le Seyec J.

Sci Rep. 2017 Aug 23;7(1):9205. doi: 10.1038/s41598-017-09789-8.

16.

Development of a Fiber-Optics Microspatially Offset Raman Spectroscopy Sensor for Probing Layered Materials.

Vandenabeele P, Conti C, Rousaki A, Moens L, Realini M, Matousek P.

Anal Chem. 2017 Sep 5;89(17):9218-9223. doi: 10.1021/acs.analchem.7b01978. Epub 2017 Aug 11.

PMID:
28753322
17.

Necroptosis: (Last) Message in a Bubble.

Vandenabeele P, Riquet F, Cappe B.

Immunity. 2017 Jul 18;47(1):1-3. doi: 10.1016/j.immuni.2017.07.002.

PMID:
28723543
18.

Sibiriline, a new small chemical inhibitor of receptor-interacting protein kinase 1, prevents immune-dependent hepatitis.

Le Cann F, Delehouzé C, Leverrier-Penna S, Filliol A, Comte A, Delalande O, Desban N, Baratte B, Gallais I, Piquet-Pellorce C, Faurez F, Bonnet M, Mettey Y, Goekjian P, Samson M, Vandenabeele P, Bach S, Dimanche-Boitrel MT.

FEBS J. 2017 Sep;284(18):3050-3068. doi: 10.1111/febs.14176. Epub 2017 Aug 11.

PMID:
28715128
19.

Sorafenib tosylate inhibits directly necrosome complex formation and protects in mouse models of inflammation and tissue injury.

Martens S, Jeong M, Tonnus W, Feldmann F, Hofmans S, Goossens V, Takahashi N, Bräsen JH, Lee EW, Van der Veken P, Joossens J, Augustyns K, Fulda S, Linkermann A, Song J, Vandenabeele P.

Cell Death Dis. 2017 Jun 29;8(6):e2904. doi: 10.1038/cddis.2017.298.

20.

The IL-33/ST2 axis is crucial in type 2 airway responses induced by Staphylococcus aureus-derived serine protease-like protein D.

Teufelberger AR, Nordengrün M, Braun H, Maes T, De Grove K, Holtappels G, O'Brien C, Provoost S, Hammad H, Gonçalves A, Beyaert R, Declercq W, Vandenabeele P, Krysko DV, Bröker BM, Bachert C, Krysko O.

J Allergy Clin Immunol. 2018 Feb;141(2):549-559.e7. doi: 10.1016/j.jaci.2017.05.004. Epub 2017 May 19.

PMID:
28532656

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