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Items: 1 to 20 of 53

1.

Evolutionary Origins of cGAS-STING Signaling.

Margolis SR, Wilson SC, Vance RE.

Trends Immunol. 2017 Apr 14. pii: S1471-4906(17)30054-6. doi: 10.1016/j.it.2017.03.004. [Epub ahead of print] Review.

PMID:
28416447
2.

NAIP-NLRC4 Inflammasomes Coordinate Intestinal Epithelial Cell Expulsion with Eicosanoid and IL-18 Release via Activation of Caspase-1 and -8.

Rauch I, Deets KA, Ji DX, von Moltke J, Tenthorey JL, Lee AY, Philip NH, Ayres JS, Brodsky IE, Gronert K, Vance RE.

Immunity. 2017 Apr 18;46(4):649-659. doi: 10.1016/j.immuni.2017.03.016. Epub 2017 Apr 11.

PMID:
28410991
3.
4.

Intracellular innate immune surveillance devices in plants and animals.

Jones JD, Vance RE, Dangl JL.

Science. 2016 Dec 2;354(6316). pii: aaf6395. Review.

PMID:
27934708
5.

Functional and Evolutionary Analyses Identify Proteolysis as a General Mechanism for NLRP1 Inflammasome Activation.

Chavarría-Smith J, Mitchell PS, Ho AM, Daugherty MD, Vance RE.

PLoS Pathog. 2016 Dec 7;12(12):e1006052. doi: 10.1371/journal.ppat.1006052. eCollection 2016 Dec.

6.

Cytosolic DNA Sensing: The Field Narrows.

Vance RE.

Immunity. 2016 Aug 16;45(2):227-8. doi: 10.1016/j.immuni.2016.08.006.

PMID:
27533006
7.

NAIP proteins are required for cytosolic detection of specific bacterial ligands in vivo.

Rauch I, Tenthorey JL, Nichols RD, Al Moussawi K, Kang JJ, Kang C, Kazmierczak BI, Vance RE.

J Exp Med. 2016 May 2;213(5):657-65. doi: 10.1084/jem.20151809. Epub 2016 Apr 4.

8.

Ancient Origin of cGAS-STING Reveals Mechanism of Universal 2',3' cGAMP Signaling.

Kranzusch PJ, Wilson SC, Lee AS, Berger JM, Doudna JA, Vance RE.

Mol Cell. 2015 Sep 17;59(6):891-903. doi: 10.1016/j.molcel.2015.07.022. Epub 2015 Aug 20.

9.

The Cytosolic Sensor cGAS Detects Mycobacterium tuberculosis DNA to Induce Type I Interferons and Activate Autophagy.

Watson RO, Bell SL, MacDuff DA, Kimmey JM, Diner EJ, Olivas J, Vance RE, Stallings CL, Virgin HW, Cox JS.

Cell Host Microbe. 2015 Jun 10;17(6):811-9. doi: 10.1016/j.chom.2015.05.004. Epub 2015 Jun 2.

10.

The NLRP1 inflammasomes.

Chavarría-Smith J, Vance RE.

Immunol Rev. 2015 May;265(1):22-34. doi: 10.1111/imr.12283. Review.

PMID:
25879281
11.

The NAIP/NLRC4 inflammasomes.

Vance RE.

Curr Opin Immunol. 2015 Feb;32:84-9. doi: 10.1016/j.coi.2015.01.010. Epub 2015 Jan 24. Review.

12.

The macrophage paradox.

Price JV, Vance RE.

Immunity. 2014 Nov 20;41(5):685-93. doi: 10.1016/j.immuni.2014.10.015. Epub 2014 Nov 1.

13.

Structure-guided reprogramming of human cGAS dinucleotide linkage specificity.

Kranzusch PJ, Lee AS, Wilson SC, Solovykh MS, Vance RE, Berger JM, Doudna JA.

Cell. 2014 Aug 28;158(5):1011-21. doi: 10.1016/j.cell.2014.07.028. Epub 2014 Aug 14.

14.

Molecular basis for specific recognition of bacterial ligands by NAIP/NLRC4 inflammasomes.

Tenthorey JL, Kofoed EM, Daugherty MD, Malik HS, Vance RE.

Mol Cell. 2014 Apr 10;54(1):17-29. doi: 10.1016/j.molcel.2014.02.018. Epub 2014 Mar 20.

15.

Frequent and seasonally variable sublethal anthrax infections are accompanied by short-lived immunity in an endemic system.

Cizauskas CA, Bellan SE, Turner WC, Vance RE, Getz WM.

J Anim Ecol. 2014 Sep;83(5):1078-90. doi: 10.1111/1365-2656.12207. Epub 2014 Mar 14.

16.

cGAS dimerization entangles DNA recognition.

Kranzusch PJ, Vance RE.

Immunity. 2013 Dec 12;39(6):992-4. doi: 10.1016/j.immuni.2013.11.012.

17.

Taking the STING out of cytosolic DNA sensing.

Diner EJ, Vance RE.

Trends Immunol. 2014 Jan;35(1):1-2. doi: 10.1016/j.it.2013.10.011. Epub 2013 Nov 11.

PMID:
24231656
18.

Blue native polyacrylamide gel electrophoresis to monitor inflammasome assembly and composition.

Kofoed EM, Vance RE.

Methods Mol Biol. 2013;1040:169-83. doi: 10.1007/978-1-62703-523-1_13.

PMID:
23852604
19.

Direct proteolytic cleavage of NLRP1B is necessary and sufficient for inflammasome activation by anthrax lethal factor.

Chavarría-Smith J, Vance RE.

PLoS Pathog. 2013;9(6):e1003452. doi: 10.1371/journal.ppat.1003452. Epub 2013 Jun 20.

20.

The innate immune DNA sensor cGAS produces a noncanonical cyclic dinucleotide that activates human STING.

Diner EJ, Burdette DL, Wilson SC, Monroe KM, Kellenberger CA, Hyodo M, Hayakawa Y, Hammond MC, Vance RE.

Cell Rep. 2013 May 30;3(5):1355-61. doi: 10.1016/j.celrep.2013.05.009. Epub 2013 May 23.

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