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Cilia and Obesity.

Vaisse C, Reiter JF, Berbari NF.

Cold Spring Harb Perspect Biol. 2017 Jan 17. pii: a028217. doi: 10.1101/cshperspect.a028217. [Epub ahead of print]


The Association of Serum Leptin with Mortality in Older Adults.

Mishra S, Harris TB, Hsueh WC, Hue T, Leak TS, Li R, Mehta M, Vaisse C, Sahyoun NR.

PLoS One. 2015 Oct 16;10(10):e0140763. doi: 10.1371/journal.pone.0140763.


Genetic association study of adiposity and melanocortin-4 receptor (MC4R) common variants: replication and functional characterization of non-coding regions.

Evans DS, Calton MA, Kim MJ, Kwok PY, Miljkovic I, Harris T, Koster A, Liu Y, Tranah GJ, Ahituv N, Hsueh WC, Vaisse C.

PLoS One. 2014 May 12;9(5):e96805. doi: 10.1371/journal.pone.0096805.


Hyperphagia: current concepts and future directions proceedings of the 2nd international conference on hyperphagia.

Heymsfield SB, Avena NM, Baier L, Brantley P, Bray GA, Burnett LC, Butler MG, Driscoll DJ, Egli D, Elmquist J, Forster JL, Goldstone AP, Gourash LM, Greenway FL, Han JC, Kane JG, Leibel RL, Loos RJ, Scheimann AO, Roth CL, Seeley RJ, Sheffield V, Tauber M, Vaisse C, Wang L, Waterland RA, Wevrick R, Yanovski JA, Zinn AR.

Obesity (Silver Spring). 2014 Feb;22 Suppl 1:S1-S17. doi: 10.1002/oby.20646.


Functional characterization of SIM1-associated enhancers.

Kim MJ, Oksenberg N, Hoffmann TJ, Vaisse C, Ahituv N.

Hum Mol Genet. 2014 Apr 1;23(7):1700-8. doi: 10.1093/hmg/ddt559.


The melanocortin system and insulin resistance in humans: insights from a patient with complete POMC deficiency and type 1 diabetes mellitus.

Aslan IR, Ranadive SA, Valle I, Kollipara S, Noble JA, Vaisse C.

Int J Obes (Lond). 2014 Jan;38(1):148-51. doi: 10.1038/ijo.2013.53.


Mechanism of N-terminal modulation of activity at the melanocortin-4 receptor GPCR.

Ersoy BA, Pardo L, Zhang S, Thompson DA, Millhauser G, Govaerts C, Vaisse C.

Nat Chem Biol. 2012 Aug;8(8):725-30. doi: 10.1038/nchembio.1008.


Replication and extension of association between common genetic variants in SIM1 and human adiposity.

Swarbrick MM, Evans DS, Valle MI, Favre H, Wu SH, Njajou OT, Li R, Zmuda JM, Miljkovic I, Harris TB, Kwok PY, Vaisse C, Hsueh WC.

Obesity (Silver Spring). 2011 Dec;19(12):2394-403. doi: 10.1038/oby.2011.79.


Weight loss after Roux-en-Y gastric bypass in obese patients heterozygous for MC4R mutations.

Aslan IR, Campos GM, Calton MA, Evans DS, Merriman RB, Vaisse C.

Obes Surg. 2011 Jul;21(7):930-4. doi: 10.1007/s11695-010-0295-8.


Changes in cortical bone response to high-fat diet from adolescence to adulthood in mice.

Ionova-Martin SS, Wade JM, Tang S, Shahnazari M, Ager JW 3rd, Lane NE, Yao W, Alliston T, Vaisse C, Ritchie RO.

Osteoporos Int. 2011 Aug;22(8):2283-93. doi: 10.1007/s00198-010-1432-x.


Bariatric surgery in a patient with complete MC4R deficiency.

Aslan IR, Ranadive SA, Ersoy BA, Rogers SJ, Lustig RH, Vaisse C.

Int J Obes (Lond). 2011 Mar;35(3):457-61. doi: 10.1038/ijo.2010.168.


Reduced size-independent mechanical properties of cortical bone in high-fat diet-induced obesity.

Ionova-Martin SS, Do SH, Barth HD, Szadkowska M, Porter AE, Ager JW 3rd, Ager JW Jr, Alliston T, Vaisse C, Ritchie RO.

Bone. 2010 Jan;46(1):217-25. doi: 10.1016/j.bone.2009.10.015.


In silico mutagenesis: a case study of the melanocortin 4 receptor.

Bromberg Y, Overton J, Vaisse C, Leibel RL, Rost B.

FASEB J. 2009 Sep;23(9):3059-69. doi: 10.1096/fj.08-127530.


Narrowing down the role of common variants in the genetic predisposition to obesity.

Calton MA, Vaisse C.

Genome Med. 2009 Mar 11;1(3):31. doi: 10.1186/gm31.


Identification, characterization and rescue of a novel vasopressin-2 receptor mutation causing nephrogenic diabetes insipidus.

Ranadive SA, Ersoy B, Favre H, Cheung CC, Rosenthal SM, Miller WL, Vaisse C.

Clin Endocrinol (Oxf). 2009 Sep;71(3):388-93. doi: 10.1111/j.1365-2265.2008.03513.x.


Association of functionally significant Melanocortin-4 but not Melanocortin-3 receptor mutations with severe adult obesity in a large North American case-control study.

Calton MA, Ersoy BA, Zhang S, Kane JP, Malloy MJ, Pullinger CR, Bromberg Y, Pennacchio LA, Dent R, McPherson R, Ahituv N, Vaisse C.

Hum Mol Genet. 2009 Mar 15;18(6):1140-7. doi: 10.1093/hmg/ddn431.


Lessons from extreme human obesity: monogenic disorders.

Ranadive SA, Vaisse C.

Endocrinol Metab Clin North Am. 2008 Sep;37(3):733-51, x. doi: 10.1016/j.ecl.2008.07.003. Review.


Unexpected endocrine features and normal pigmentation in a young adult patient carrying a novel homozygous mutation in the POMC gene.

Clément K, Dubern B, Mencarelli M, Czernichow P, Ito S, Wakamatsu K, Barsh GS, Vaisse C, Leger J.

J Clin Endocrinol Metab. 2008 Dec;93(12):4955-62. doi: 10.1210/jc.2008-1164.


Gender and neurogenin3 influence the pathogenesis of ketosis-prone diabetes.

Louet JF, Smith SB, Gautier JF, Molokhia M, Virally ML, Kevorkian JP, Guillausseau PJ, Vexiau P, Charpentier G, German MS, Vaisse C, Urbanek M, Mauvais-Jarvis F.

Diabetes Obes Metab. 2008 Sep;10(10):912-20.


Mutational analysis of the pro-opiomelanocortin gene in French obese children led to the identification of a novel deleterious heterozygous mutation located in the alpha-melanocyte stimulating hormone domain.

Dubern B, Lubrano-Berthelier C, Mencarelli M, Ersoy B, Frelut ML, Bouglé D, Costes B, Simon C, Tounian P, Vaisse C, Clement K.

Pediatr Res. 2008 Feb;63(2):211-6.

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