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Items: 18


Identification and Characterization of Novel Compounds Blocking Shiga Toxin Expression in Escherichia coli O157:H7.

Huerta-Uribe A, Marjenberg ZR, Yamaguchi N, Fitzgerald S, Connolly JP, Carpena N, Uvell H, Douce G, Elofsson M, Byron O, Marquez R, Gally DL, Roe AJ.

Front Microbiol. 2016 Nov 30;7:1930. eCollection 2016.


Dibenzocyclooctadiene lignans from Schisandra spp. selectively inhibit the growth of the intracellular bacteria Chlamydia pneumoniae and Chlamydia trachomatis.

Hakala E, Hanski L, Uvell H, Yrjönen T, Vuorela H, Elofsson M, Vuorela PM.

J Antibiot (Tokyo). 2015 Oct;68(10):609-14. doi: 10.1038/ja.2015.48. Epub 2015 May 6.


Inhibitory activity of the isoflavone biochanin A on intracellular bacteria of genus Chlamydia and initial development of a buccal formulation.

Hanski L, Genina N, Uvell H, Malinovskaja K, Gylfe Å, Laaksonen T, Kolakovic R, Mäkilä E, Salonen J, Hirvonen J, Elofsson M, Sandler N, Vuorela PM.

PLoS One. 2014 Dec 16;9(12):e115115. doi: 10.1371/journal.pone.0115115. eCollection 2014.


Novel high-throughput screening method for identification of fungal dimorphism blockers.

Stylianou M, Uvell H, Lopes JP, Enquist PA, Elofsson M, Urban CF.

J Biomol Screen. 2015 Feb;20(2):285-91. doi: 10.1177/1087057114552954. Epub 2014 Oct 3.


N-acylated derivatives of sulfamethoxazole and sulfafurazole inhibit intracellular growth of Chlamydia trachomatis.

Marwaha S, Uvell H, Salin O, Lindgren AE, Silver J, Elofsson M, Gylfe A.

Antimicrob Agents Chemother. 2014 May;58(5):2968-71. doi: 10.1128/AAC.02015-13. Epub 2014 Feb 24.


Syntheses and biological evaluation of 2-amino-3-acyl-tetrahydrobenzothiophene derivatives; antibacterial agents with antivirulence activity.

Dang HT, Chorell E, Uvell H, Pinkner JS, Hultgren SJ, Almqvist F.

Org Biomol Chem. 2014 Mar 28;12(12):1942-56. doi: 10.1039/c3ob42478b. Epub 2014 Feb 17.


Isolation and characterization of anti-adenoviral secondary metabolites from marine actinobacteria.

Strand M, Carlsson M, Uvell H, Islam K, Edlund K, Cullman I, Altermark B, Mei YF, Elofsson M, Willassen NP, Wadell G, Almqvist F.

Mar Drugs. 2014 Jan 28;12(2):799-821. doi: 10.3390/md12020799.


The Oct1 homolog Nubbin is a repressor of NF-κB-dependent immune gene expression that increases the tolerance to gut microbiota.

Dantoft W, Davis MM, Lindvall JM, Tang X, Uvell H, Junell A, Beskow A, Engström Y.

BMC Biol. 2013 Sep 6;11:99. doi: 10.1186/1741-7007-11-99.


Functional studies of the yeast med5, med15 and med16 mediator tail subunits.

Larsson M, Uvell H, Sandström J, Rydén P, Selth LA, Björklund S.

PLoS One. 2013 Aug 22;8(8):e73137. doi: 10.1371/journal.pone.0073137. eCollection 2013.


Design, synthesis and evaluation of triazole functionalized ring-fused 2-pyridones as antibacterial agents.

Bengtsson C, Lindgren AE, Uvell H, Almqvist F.

Eur J Med Chem. 2012 Aug;54:637-46. doi: 10.1016/j.ejmech.2012.06.018. Epub 2012 Jun 18.


Identification of bacterial target proteins for the salicylidene acylhydrazide class of virulence-blocking compounds.

Wang D, Zetterström CE, Gabrielsen M, Beckham KS, Tree JJ, Macdonald SE, Byron O, Mitchell TJ, Gally DL, Herzyk P, Mahajan A, Uvell H, Burchmore R, Smith BO, Elofsson M, Roe AJ.

J Biol Chem. 2011 Aug 26;286(34):29922-31. doi: 10.1074/jbc.M111.233858. Epub 2011 Jul 1.


Synthesis and application of a bromomethyl substituted scaffold to be used for efficient optimization of anti-virulence activity.

Chorell E, Bengtsson C, Sainte-Luce Banchelin T, Das P, Uvell H, Sinha AK, Pinkner JS, Hultgren SJ, Almqvist F.

Eur J Med Chem. 2011 Apr;46(4):1103-16. doi: 10.1016/j.ejmech.2011.01.025. Epub 2011 Jan 21.


The POU transcription factor Drifter/Ventral veinless regulates expression of Drosophila immune defense genes.

Junell A, Uvell H, Davis MM, Edlundh-Rose E, Antonsson A, Pick L, Engström Y.

Mol Cell Biol. 2010 Jul;30(14):3672-84. doi: 10.1128/MCB.00223-10. Epub 2010 May 10.


A multilayered defense against infection: combinatorial control of insect immune genes.

Uvell H, Engström Y.

Trends Genet. 2007 Jul;23(7):342-9. Epub 2007 May 29. Review.


Isolation of regulators of Drosophila immune defense genes by a double interaction screen in yeast.

Junell A, Uvell H, Pick L, Engström Y.

Insect Biochem Mol Biol. 2007 Mar;37(3):202-12. Epub 2006 Nov 7.


Cooperative control of Drosophila immune responses by the JNK and NF-kappaB signaling pathways.

Delaney JR, Stöven S, Uvell H, Anderson KV, Engström Y, Mlodzik M.

EMBO J. 2006 Jul 12;25(13):3068-77. Epub 2006 Jun 8.


Targeting bacterial virulence: inhibitors of type III secretion in Yersinia.

Kauppi AM, Nordfelth R, Uvell H, Wolf-Watz H, Elofsson M.

Chem Biol. 2003 Mar;10(3):241-9.

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