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The role of α9β1 integrin and its ligands in the development of autoimmune diseases.

Kon S, Uede T.

J Cell Commun Signal. 2017 Oct 3. doi: 10.1007/s12079-017-0413-7. [Epub ahead of print]


Comparison of the antiviral potential among soluble forms of herpes simplex virus type-2 glycoprotein D receptors, herpes virus entry mediator A, nectin-1 and nectin-2, in transgenic mice.

Fujimoto Y, Tomioka Y, Ozaki K, Takeda K, Suyama H, Yamamoto S, Takakuwa H, Morimatsu M, Uede T, Ono E.

J Gen Virol. 2017 Jul;98(7):1815-1822. doi: 10.1099/jgv.0.000804. Epub 2017 Jul 24.


A Novel α9 Integrin Ligand, XCL1/Lymphotactin, Is Involved in the Development of Murine Models of Autoimmune Diseases.

Matsumoto N, Kon S, Nakatsuru T, Miyashita T, Inui K, Saitoh K, Kitai Y, Muromoto R, Kashiwakura JI, Uede T, Matsuda T.

J Immunol. 2017 Jul 1;199(1):82-90. doi: 10.4049/jimmunol.1601329. Epub 2017 May 26.


Osteopontin attenuates acute gastrointestinal graft-versus-host disease by preventing apoptosis of intestinal epithelial cells.

Kawakami K, Minami N, Matsuura M, Iida T, Toyonaga T, Nagaishi K, Arimura Y, Fujimiya M, Uede T, Nakase H.

Biochem Biophys Res Commun. 2017 Apr 1;485(2):468-475. doi: 10.1016/j.bbrc.2017.02.047. Epub 2017 Feb 9.


Death receptor 6 contributes to autoimmunity in lupus-prone mice.

Fujikura D, Ikesue M, Endo T, Chiba S, Higashi H, Uede T.

Nat Commun. 2017 Jan 3;8:13957. doi: 10.1038/ncomms13957.


High salt diet stimulates gut Th17 response and exacerbates TNBS-induced colitis in mice.

Wei Y, Lu C, Chen J, Cui G, Wang L, Yu T, Yang Y, Wu W, Ding Y, Li L, Uede T, Chen Z, Diao H.

Oncotarget. 2017 Jan 3;8(1):70-82. doi: 10.18632/oncotarget.13783.


G-CSF-induced sympathetic tone provokes fever and primes antimobilizing functions of neutrophils via PGE2.

Kawano Y, Fukui C, Shinohara M, Wakahashi K, Ishii S, Suzuki T, Sato M, Asada N, Kawano H, Minagawa K, Sada A, Furuyashiki T, Uematsu S, Akira S, Uede T, Narumiya S, Matsui T, Katayama Y.

Blood. 2017 Feb 2;129(5):587-597. doi: 10.1182/blood-2016-07-725754. Epub 2016 Nov 8.


Enterogenous bacterial glycolipids are required for the generation of natural killer T cells mediated liver injury.

Wei Y, Zeng B, Chen J, Cui G, Lu C, Wu W, Yang J, Wei H, Xue R, Bai L, Chen Z, Li L, Iwabuchi K, Uede T, Van Kaer L, Diao H.

Sci Rep. 2016 Nov 8;6:36365. doi: 10.1038/srep36365.


Adenovirus-Mediated ICOSIg Gene Therapy in a Presensitized Murine Model of Allergic Rhinitis.

Sato J, Konno N, Murakami M, Uede T, Himi T.

Adv Otorhinolaryngol. 2016;77:59-66. doi: 10.1159/000441876. Epub 2016 Apr 26.


Influence of Peri-Operative Hypothermia on Surgical Site Infection in Prolonged Gastroenterological Surgery.

Tsuchida T, Takesue Y, Ichiki K, Uede T, Nakajima K, Ikeuchi H, Uchino M.

Surg Infect (Larchmt). 2016 Oct;17(5):570-6. doi: 10.1089/sur.2015.182. Epub 2016 Mar 30.


Severe Infection With Avian Influenza A Virus is Associated With Delayed Immune Recovery in Survivors.

Chen J, Cui G, Lu C, Ding Y, Gao H, Zhu Y, Wei Y, Wang L, Uede T, Li L, Diao H.

Medicine (Baltimore). 2016 Feb;95(5):e2606. doi: 10.1097/MD.0000000000002606.


Osteopontin-integrin interaction as a novel molecular target for antibody-mediated immunotherapy in adult T-cell leukemia.

Maeda N, Ohashi T, Chagan-Yasutan H, Hattori T, Takahashi Y, Harigae H, Hasegawa H, Yamada Y, Fujii M, Maenaka K, Uede T.

Retrovirology. 2015 Nov 24;12:99. doi: 10.1186/s12977-015-0225-x.


Decreased Osteopontin Expression as a Reliable Prognostic Indicator of Improvement in Pulmonary Tuberculosis: Impact of the Level of Interferon-gamma-Inducible Protein 10.

Zhu Y, Jia H, Chen J, Cui G, Gao H, Wei Y, Lu C, Wang L, Uede T, Diao H.

Cell Physiol Biochem. 2015;37(5):1983-96. doi: 10.1159/000438559. Epub 2015 Nov 20.


Integrin Alpha-9 Mediates Lymphatic Valve Formation in Corneal Lymphangiogenesis.

Altiok E, Ecoiffier T, Sessa R, Yuen D, Grimaldo S, Tran C, Li D, Rosner M, Lee N, Uede T, Chen L.

Invest Ophthalmol Vis Sci. 2015 Oct;56(11):6313-9. doi: 10.1167/iovs.15-17509.


Regular Exercise Enhances the Immune Response Against Microbial Antigens Through Up-Regulation of Toll-like Receptor Signaling Pathways.

Zheng Q, Cui G, Chen J, Gao H, Wei Y, Uede T, Chen Z, Diao H.

Cell Physiol Biochem. 2015;37(2):735-46. doi: 10.1159/000430391. Epub 2015 Sep 11.


Syndecan 4 Mediates Nrf2-dependent Expansion of Bronchiolar Progenitors That Protect Against Lung Inflammation.

Santoso A, Kikuchi T, Tode N, Hirano T, Komatsu R, Damayanti T, Motohashi H, Yamamoto M, Kojima T, Uede T, Nukiwa T, Ichinose M.

Mol Ther. 2016 Feb;24(1):41-52. doi: 10.1038/mt.2015.153. Epub 2015 Aug 26.


Osteopontin Deficiency Accelerates Spontaneous Colitis in Mice with Disrupted Gut Microbiota and Macrophage Phagocytic Activity.

Toyonaga T, Nakase H, Ueno S, Matsuura M, Yoshino T, Honzawa Y, Itou A, Namba K, Minami N, Yamada S, Koshikawa Y, Uede T, Chiba T, Okazaki K.

PLoS One. 2015 Aug 14;10(8):e0135552. doi: 10.1371/journal.pone.0135552. eCollection 2015.


Oral administration of the Aureobasidium pullulans-derived β-glucan effectively prevents the development of high fat diet-induced fatty liver in mice.

Aoki S, Iwai A, Kawata K, Muramatsu D, Uchiyama H, Okabe M, Ikesue M, Maeda N, Uede T.

Sci Rep. 2015 Jul 16;5:10457. doi: 10.1038/srep10457.


Osteopontin promotes dendritic cell maturation and function in response to HBV antigens.

Cui G, Chen J, He J, Lu C, Wei Y, Wang L, Xu X, Li L, Uede T, Diao H.

Drug Des Devel Ther. 2015 Jun 12;9:3003-16. doi: 10.2147/DDDT.S81656. eCollection 2015.


Syndecan 4 Regulation of the Development of Autoimmune Arthritis in Mice by Modulating B Cell Migration and Germinal Center Formation.

Endo T, Ito K, Morimoto J, Kanayama M, Ota D, Ikesue M, Kon S, Takahashi D, Onodera T, Iwasaki N, Uede T.

Arthritis Rheumatol. 2015 Sep;67(9):2512-22. doi: 10.1002/art.39193.

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