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Estrogen receptor-alpha isoforms are the main estrogen receptors expressed in non-small cell lung carcinoma.

Pelekanou V, Anastasiou E, Bakogeorgou E, Notas G, Kampa M, Garcia-Milian R, Lavredaki K, Moustou E, Chinari G, Arapantoni P, O'Grady A, Georgoulias V, Tsapis A, Stathopoulos EN, Castanas E.

Steroids. 2018 Feb 15. pii: S0039-128X(18)30016-3. doi: 10.1016/j.steroids.2018.01.008. [Epub ahead of print]


Androgen Triggers the Pro-Migratory CXCL12/CXCR4 Axis in AR-Positive Breast Cancer Cell Lines: Underlying Mechanism and Possible Implications for the Use of Aromatase Inhibitors in Breast Cancer.

Azariadis K, Kiagiadaki F, Pelekanou V, Bempi V, Alexakis K, Kampa M, Tsapis A, Castanas E, Notas G.

Cell Physiol Biochem. 2017;44(1):66-84. doi: 10.1159/000484584. Epub 2017 Nov 3.


Estrogen anti-inflammatory activity on human monocytes is mediated through cross-talk between estrogen receptor ERα36 and GPR30/GPER1.

Pelekanou V, Kampa M, Kiagiadaki F, Deli A, Theodoropoulos P, Agrogiannis G, Patsouris E, Tsapis A, Castanas E, Notas G.

J Leukoc Biol. 2016 Feb;99(2):333-47. doi: 10.1189/jlb.3A0914-430RR. Epub 2015 Sep 22.


Tamoxifen induces a pluripotency signature in breast cancer cells and human tumors.

Notas G, Pelekanou V, Kampa M, Alexakis K, Sfakianakis S, Laliotis A, Askoxilakis J, Tsentelierou E, Tzardi M, Tsapis A, Castanas E.

Mol Oncol. 2015 Nov;9(9):1744-59. doi: 10.1016/j.molonc.2015.05.008. Epub 2015 Jun 5.


BAFF, APRIL, TWEAK, BCMA, TACI and Fn14 proteins are related to human glioma tumor grade: immunohistochemistry and public microarray data meta-analysis.

Pelekanou V, Notas G, Kampa M, Tsentelierou E, Stathopoulos EN, Tsapis A, Castanas E.

PLoS One. 2013 Dec 20;8(12):e83250. doi: 10.1371/journal.pone.0083250. eCollection 2013.


APRIL binding to BCMA activates a JNK2-FOXO3-GADD45 pathway and induces a G2/M cell growth arrest in liver cells.

Notas G, Alexaki VI, Kampa M, Pelekanou V, Charalampopoulos I, Sabour-Alaoui S, Pediaditakis I, Dessirier V, Gravanis A, Stathopoulos EN, Tsapis A, Castanas E.

J Immunol. 2012 Nov 15;189(10):4748-58. doi: 10.4049/jimmunol.1102891. Epub 2012 Oct 15.


TWEAK affects keratinocyte G2/M growth arrest and induces apoptosis through the translocation of the AIF protein to the nucleus.

Sabour Alaoui S, Dessirier V, de Araujo E, Alexaki VI, Pelekanou V, Lkhider M, Stathopoulos EN, Castanas E, Bagot M, Bensussan A, Tsapis A.

PLoS One. 2012;7(3):e33609. doi: 10.1371/journal.pone.0033609. Epub 2012 Mar 16.


B-cell maturation antigen (BCMA) activation exerts specific proinflammatory effects in normal human keratinocytes and is preferentially expressed in inflammatory skin pathologies.

Alexaki VI, Pelekanou V, Notas G, Venihaki M, Kampa M, Dessirier V, Sabour-Alaoui S, Stathopoulos EN, Tsapis A, Castanas E.

Endocrinology. 2012 Feb;153(2):739-49. doi: 10.1210/en.2011-1504. Epub 2011 Dec 13.


Detection of the TNFSF members BAFF, APRIL, TWEAK and their receptors in normal kidney and renal cell carcinomas.

Pelekanou V, Notas G, Theodoropoulou K, Kampa M, Takos D, Alexaki VI, Radojicic J, Sofras F, Tsapis A, Stathopoulos EN, Castanas E.

Anal Cell Pathol (Amst). 2011;34(1-2):49-60. doi: 10.3233/ACP-2011-0001.


Death ligand TRAIL, secreted by CD1a+ and CD14+ cells in blister fluids, is involved in killing keratinocytes in toxic epidermal necrolysis.

de Araujo E, Dessirier V, Laprée G, Valeyrie-Allanore L, Ortonne N, Stathopoulos EN, Bagot M, Bensussan A, Mockenhaupt M, Roujeau JC, Tsapis A.

Exp Dermatol. 2011 Feb;20(2):107-12. doi: 10.1111/j.1600-0625.2010.01176.x.


Testosterone membrane-initiated action in breast cancer cells: Interaction with the androgen signaling pathway and EPOR.

Pelekanou V, Notas G, Sanidas E, Tsapis A, Castanas E, Kampa M.

Mol Oncol. 2010 Apr;4(2):135-49. doi: 10.1016/j.molonc.2010.01.004. Epub 2010 Feb 2.


Adipocytes as immune cells: differential expression of TWEAK, BAFF, and APRIL and their receptors (Fn14, BAFF-R, TACI, and BCMA) at different stages of normal and pathological adipose tissue development.

Alexaki VI, Notas G, Pelekanou V, Kampa M, Valkanou M, Theodoropoulos P, Stathopoulos EN, Tsapis A, Castanas E.

J Immunol. 2009 Nov 1;183(9):5948-56. doi: 10.4049/jimmunol.0901186. Epub 2009 Oct 14.


Expression of TNF-superfamily members BAFF and APRIL in breast cancer: immunohistochemical study in 52 invasive ductal breast carcinomas.

Pelekanou V, Kampa M, Kafousi M, Darivianaki K, Sanidas E, Tsiftsis DD, Stathopoulos EN, Tsapis A, Castanas E.

BMC Cancer. 2008 Mar 20;8:76. doi: 10.1186/1471-2407-8-76.


BAFF enhances chemotaxis of primary human B cells: a particular synergy between BAFF and CXCL13 on memory B cells.

Badr G, Borhis G, Lefevre EA, Chaoul N, Deshayes F, Dessirier V, Lapree G, Tsapis A, Richard Y.

Blood. 2008 Mar 1;111(5):2744-54. doi: 10.1182/blood-2007-03-081232. Epub 2008 Jan 2.


Abnormal production of the TNF-homologue APRIL increases the proliferation of human malignant glioblastoma cell lines via a specific receptor.

Deshayes F, Laprée G, Portier A, Richard Y, Pencalet P, Mahieu-Caputo D, Horellou P, Tsapis A.

Oncogene. 2004 Apr 15;23(17):3005-12.


Natural antisense RNA inhibits the expression of BCMA, a tumour necrosis factor receptor homologue.

Hatzoglou A, Deshayes F, Madry C, Laprée G, Castanas E, Tsapis A.

BMC Mol Biol. 2002 Apr 18;3:4. Epub 2002 Apr 18.


BAFF binds to the tumor necrosis factor receptor-like molecule B cell maturation antigen and is important for maintaining the peripheral B cell population.

Thompson JS, Schneider P, Kalled SL, Wang L, Lefevre EA, Cachero TG, MacKay F, Bixler SA, Zafari M, Liu ZY, Woodcock SA, Qian F, Batten M, Madry C, Richard Y, Benjamin CD, Browning JL, Tsapis A, Tschopp J, Ambrose C.

J Exp Med. 2000 Jul 3;192(1):129-35.


The characterization of murine BCMA gene defines it as a new member of the tumor necrosis factor receptor superfamily.

Madry C, Laabi Y, Callebaut I, Roussel J, Hatzoglou A, Le Coniat M, Mornon JP, Berger R, Tsapis A.

Int Immunol. 1998 Nov;10(11):1693-702.


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