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Items: 1 to 20 of 80

1.

Extended post-mortem delay times should not be viewed as a deterrent to the scientific investigation of human brain tissue: a study from the Brains for Dementia Research Network Neuropathology Study Group, UK.

Robinson AC, Palmer L, Love S, Hamard M, Esiri M, Ansorge O, Lett D, Attems J, Morris C, Troakes C, Selvackadunco S, King A, Al-Sarraj S, Mann DM.

Acta Neuropathol. 2016 Nov;132(5):753-755. No abstract available.

PMID:
27638700
2.

The Identification of Aluminum in Human Brain Tissue Using Lumogallion and Fluorescence Microscopy.

Mirza A, King A, Troakes C, Exley C.

J Alzheimers Dis. 2016 Oct 18;54(4):1333-1338.

3.

In vitro prion-like behaviour of TDP-43 in ALS.

Smethurst P, Newcombe J, Troakes C, Simone R, Chen YR, Patani R, Sidle K.

Neurobiol Dis. 2016 Dec;96:236-247. doi: 10.1016/j.nbd.2016.08.007.

4.

Analysis of C9orf72 repeat expansions in a large international cohort of dementia with Lewy bodies.

Kun-Rodrigues C, Ross OA, Orme T, Shepherd C, Parkkinen L, Darwent L, Hernandez D, Ansorge O, Clark LN, Honig LS, Marder K, Lemstra A, Scheltens P, van der Flier W, Louwersheimer E, Holstege H, Rogaeva E, St George-Hyslop P, Londos E, Zetterberg H, Barber I, Braae A, Brown K, Morgan K, Maetzler W, Berg D, Troakes C, Al-Sarraj S, Lashley T, Holton J, Compta Y, Van Deerlin V, Trojanowski JQ, Serrano GE, Beach TG, Clarimon J, Lleó A, Morenas-Rodríguez E, Lesage S, Galasko D, Masliah E, Santana I, Diez M, Pastor P, Tienari PJ, Myllykangas L, Oinas M, Revesz T, Lees A, Boeve BF, Petersen RC, Ferman TJ, Escott-Price V, Graff-Radford N, Cairns NJ, Morris JC, Stone DJ, Pickering-Brown S, Mann D, Dickson DW, Halliday GM, Singleton A, Guerreiro R, Bras J.

Neurobiol Aging. 2016 Sep 2. pii: S0197-4580(16)30201-9. doi: 10.1016/j.neurobiolaging.2016.08.023. [Epub ahead of print]

PMID:
27666590
5.

Alzheimer-related decrease in CYFIP2 links amyloid production to tau hyperphosphorylation and memory loss.

Tiwari SS, Mizuno K, Ghosh A, Aziz W, Troakes C, Daoud J, Golash V, Noble W, Hortobágyi T, Giese KP.

Brain. 2016 Oct;139(Pt 10):2751-2765.

6.

NEK1 variants confer susceptibility to amyotrophic lateral sclerosis.

Kenna KP, van Doormaal PT, Dekker AM, Ticozzi N, Kenna BJ, Diekstra FP, van Rheenen W, van Eijk KR, Jones AR, Keagle P, Shatunov A, Sproviero W, Smith BN, van Es MA, Topp SD, Kenna A, Miller JW, Fallini C, Tiloca C, McLaughlin RL, Vance C, Troakes C, Colombrita C, Mora G, Calvo A, Verde F, Al-Sarraj S, King A, Calini D, de Belleroche J, Baas F, van der Kooi AJ, de Visser M, Ten Asbroek AL, Sapp PC, McKenna-Yasek D, Polak M, Asress S, Muñoz-Blanco JL, Strom TM, Meitinger T, Morrison KE; SLAGEN Consortium., Lauria G, Williams KL, Leigh PN, Nicholson GA, Blair IP, Leblond CS, Dion PA, Rouleau GA, Pall H, Shaw PJ, Turner MR, Talbot K, Taroni F, Boylan KB, Van Blitterswijk M, Rademakers R, Esteban-Pérez J, García-Redondo A, Van Damme P, Robberecht W, Chio A, Gellera C, Drepper C, Sendtner M, Ratti A, Glass JD, Mora JS, Basak NA, Hardiman O, Ludolph AC, Andersen PM, Weishaupt JH, Brown RH Jr, Al-Chalabi A, Silani V, Shaw CE, van den Berg LH, Veldink JH, Landers JE.

Nat Genet. 2016 Sep;48(9):1037-42. doi: 10.1038/ng.3626.

PMID:
27455347
7.

Clusterin expression is upregulated following acute head injury and localizes to astrocytes in old head injury.

Troakes C, Smyth R, Noor F, Maekawa S, Killick R, King A, Al-Sarraj S.

Neuropathology. 2016 Jul 1. doi: 10.1111/neup.12320. [Epub ahead of print]

PMID:
27365216
8.

Erratum to: Variation in 5-hydroxymethylcytosine across human cortex and cerebellum.

Lunnon K, Hannon E, G Smith R, Dempster E, Wong C, Burrage J, Troakes C, Al-Sarraj S, Kepa A, Schalkwyk L, Mill J.

Genome Biol. 2016 Jun 17;17(1):131. No abstract available.

9.

ABCA7 p.G215S as potential protective factor for Alzheimer's disease.

Sassi C, Nalls MA, Ridge PG, Gibbs JR, Ding J, Lupton MK, Troakes C, Lunnon K, Al-Sarraj S, Brown KS, Medway C, Clement N, Lord J, Turton J, Bras J, Almeida MR; ARUK Consortium., Holstege H, Louwersheimer E, van der Flier WM, Scheltens P, Van Swieten JC, Santana I, Oliveira C, Morgan K, Powell JF, Kauwe JS, Cruchaga C, Goate AM, Singleton AB, Guerreiro R, Hardy J.

Neurobiol Aging. 2016 Oct;46:235.e1-9. doi: 10.1016/j.neurobiolaging.2016.04.004.

10.

Influence of Coding Variability in APP-Aβ Metabolism Genes in Sporadic Alzheimer's Disease.

Sassi C, Ridge PG, Nalls MA, Gibbs R, Ding J, Lupton MK, Troakes C, Lunnon K, Al-Sarraj S, Brown KS, Medway C, Lord J, Turton J; ARUK Consortium., Morgan K, Powell JF, Kauwe JS, Cruchaga C, Bras J, Goate AM, Singleton AB, Guerreiro R, Hardy J.

PLoS One. 2016 Jun 1;11(6):e0150079. doi: 10.1371/journal.pone.0150079.

11.

Agonist and antagonist bind differently to 5-HT1A receptors during Alzheimer's disease: A post-mortem study with PET radiopharmaceuticals.

Vidal B, Sebti J, Verdurand M, Fieux S, Billard T, Streichenberger N, Troakes C, Newman-Tancredi A, Zimmer L.

Neuropharmacology. 2016 Oct;109:88-95. doi: 10.1016/j.neuropharm.2016.05.009.

PMID:
27183968
12.

Upregulation of calpain activity precedes tau phosphorylation and loss of synaptic proteins in Alzheimer's disease brain.

Kurbatskaya K, Phillips EC, Croft CL, Dentoni G, Hughes MM, Wade MA, Al-Sarraj S, Troakes C, O'Neill MJ, Perez-Nievas BG, Hanger DP, Noble W.

Acta Neuropathol Commun. 2016 Mar 31;4:34. doi: 10.1186/s40478-016-0299-2.

13.

Genome-wide significant schizophrenia risk variation on chromosome 10q24 is associated with altered cis-regulation of BORCS7, AS3MT, and NT5C2 in the human brain.

Duarte RR, Troakes C, Nolan M, Srivastava DP, Murray RM, Bray NJ.

Am J Med Genet B Neuropsychiatr Genet. 2016 Sep;171(6):806-14. doi: 10.1002/ajmg.b.32445.

14.

Retention of hexanucleotide repeat-containing intron in C9orf72 mRNA: implications for the pathogenesis of ALS/FTD.

Niblock M, Smith BN, Lee YB, Sardone V, Topp S, Troakes C, Al-Sarraj S, Leblond CS, Dion PA, Rouleau GA, Shaw CE, Gallo JM.

Acta Neuropathol Commun. 2016 Feb 25;4:18. doi: 10.1186/s40478-016-0289-4.

15.

Variation in 5-hydroxymethylcytosine across human cortex and cerebellum.

Lunnon K, Hannon E, Smith RG, Dempster E, Wong C, Burrage J, Troakes C, Al-Sarraj S, Kepa A, Schalkwyk L, Mill J.

Genome Biol. 2016 Feb 16;17:27. doi: 10.1186/s13059-016-0871-x. Erratum in: Genome Biol. 2016;17(1):131.

16.

Tissue-specific patterns of allelically-skewed DNA methylation.

Marzi SJ, Meaburn EL, Dempster EL, Lunnon K, Paya-Cano JL, Smith RG, Volta M, Troakes C, Schalkwyk LC, Mill J.

Epigenetics. 2016;11(1):24-35. doi: 10.1080/15592294.2015.1127479.

17.

Genome-wide analysis of genetic correlation in dementia with Lewy bodies, Parkinson's and Alzheimer's diseases.

Guerreiro R, Escott-Price V, Darwent L, Parkkinen L, Ansorge O, Hernandez DG, Nalls MA, Clark L, Honig L, Marder K, van der Flier W, Holstege H, Louwersheimer E, Lemstra A, Scheltens P, Rogaeva E, St George-Hyslop P, Londos E, Zetterberg H, Ortega-Cubero S, Pastor P, Ferman TJ, Graff-Radford NR, Ross OA, Barber I, Braae A, Brown K, Morgan K, Maetzler W, Berg D, Troakes C, Al-Sarraj S, Lashley T, Compta Y, Revesz T, Lees A, Cairns NJ, Halliday GM, Mann D, Pickering-Brown S, Powell J, Lunnon K, Lupton MK; International Parkinson's Disease Genomics Consortium., Dickson D, Hardy J, Singleton A, Bras J.

Neurobiol Aging. 2016 Feb;38:214.e7-10. doi: 10.1016/j.neurobiolaging.2015.10.028.

18.

Methylation QTLs in the developing brain and their enrichment in schizophrenia risk loci.

Hannon E, Spiers H, Viana J, Pidsley R, Burrage J, Murphy TM, Troakes C, Turecki G, O'Donovan MC, Schalkwyk LC, Bray NJ, Mill J.

Nat Neurosci. 2016 Jan;19(1):48-54. doi: 10.1038/nn.4182.

19.

Neurodegeneration in frontotemporal lobar degeneration and motor neurone disease associated with expansions in C9orf72 is linked to TDP-43 pathology and not associated with aggregated forms of dipeptide repeat proteins.

Davidson Y, Robinson AC, Liu X, Wu D, Troakes C, Rollinson S, Masuda-Suzukake M, Suzuki G, Nonaka T, Shi J, Tian J, Hamdalla H, Ealing J, Richardson A, Jones M, Pickering-Brown S, Snowden JS, Hasegawa M, Mann DM.

Neuropathol Appl Neurobiol. 2016 Apr;42(3):242-54. doi: 10.1111/nan.12292.

20.

Lack of association between TDP-43 pathology and tau mis-splicing in Alzheimer's disease.

Niblock M, Hortobágyi T, Troakes C, Al-Sarraj S, Spickett C, Jones R, Shaw CE, Gallo JM.

Neurobiol Aging. 2016 Jan;37:45-6. doi: 10.1016/j.neurobiolaging.2015.09.022.

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