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Page 1
Artemisinin triggers a G1 cell cycle arrest of human Ishikawa endometrial cancer cells and inhibits cyclin-dependent kinase-4 promoter activity and expression by disrupting nuclear factor-κB transcriptional signaling.
Anticancer Drugs. 2014 Mar;25(3):270-81. doi: 10.1097/CAD.0000000000000054.
Anticancer Drugs. 2014.
PMID: 24296733
Free PMC article.
Indole-3-carbinol downregulation of telomerase gene expression requires the inhibition of estrogen receptor-alpha and Sp1 transcription factor interactions within the hTERT promoter and mediates the G1 cell cycle arrest of human breast cancer cells.
Marconett CN, Sundar SN, Tseng M, Tin AS, Tran KQ, Mahuron KM, Bjeldanes LF, Firestone GL.
Marconett CN, et al. Among authors: tran kq.
Carcinogenesis. 2011 Sep;32(9):1315-23. doi: 10.1093/carcin/bgr116. Epub 2011 Jun 21.
Carcinogenesis. 2011.
PMID: 21693539
Free PMC article.
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Antiproliferative effects of artemisinin on human breast cancer cells requires the downregulated expression of the E2F1 transcription factor and loss of E2F1-target cell cycle genes.
Tin AS, Sundar SN, Tran KQ, Park AH, Poindexter KM, Firestone GL.
Tin AS, et al. Among authors: tran kq.
Anticancer Drugs. 2012 Apr;23(4):370-9. doi: 10.1097/CAD.0b013e32834f6ea8.
Anticancer Drugs. 2012.
PMID: 22185819
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