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Items: 20


Cyclotron production and radiochemical separation of 55Co and 58mCo from 54Fe, 58Ni and 57Fe targets.

Valdovinos HF, Hernandez R, Graves S, Ellison PA, Barnhart TE, Theuer CP, Engle JW, Cai W, Nickles RJ.

Appl Radiat Isot. 2017 Dec;130:90-101. doi: 10.1016/j.apradiso.2017.09.005. Epub 2017 Sep 6.


Targeting angiogenesis for radioimmunotherapy with a 177Lu-labeled antibody.

Ehlerding EB, Lacognata S, Jiang D, Ferreira CA, Goel S, Hernandez R, Jeffery JJ, Theuer CP, Cai W.

Eur J Nucl Med Mol Imaging. 2017 Aug 18. doi: 10.1007/s00259-017-3793-2. [Epub ahead of print]


Endoglin: a novel target for therapeutic intervention in acute leukemias revealed in xenograft mouse models.

Dourado KMC, Baik J, Oliveira VKP, Beltrame M, Yamamoto A, Theuer CP, Figueiredo CAV, Verneris MR, Perlingeiro RCR.

Blood. 2017 May 4;129(18):2526-2536. doi: 10.1182/blood-2017-01-763581. Epub 2017 Mar 28.


ImmunoPET and Near-Infrared Fluorescence Imaging of Pancreatic Cancer with a Dual-Labeled Bispecific Antibody Fragment.

Luo H, England CG, Goel S, Graves SA, Ai F, Liu B, Theuer CP, Wong HC, Nickles RJ, Cai W.

Mol Pharm. 2017 May 1;14(5):1646-1655. doi: 10.1021/acs.molpharmaceut.6b01123. Epub 2017 Mar 24.


Engineering Intrinsically Zirconium-89 Radiolabeled Self-Destructing Mesoporous Silica Nanostructures for In Vivo Biodistribution and Tumor Targeting Studies.

Goel S, Chen F, Luan S, Valdovinos HF, Shi S, Graves SA, Ai F, Barnhart TE, Theuer CP, Cai W.

Adv Sci (Weinh). 2016 May 27;3(11):1600122. eCollection 2016 Nov.


Dual Targeting of Tissue Factor and CD105 for Preclinical PET Imaging of Pancreatic Cancer.

Luo H, England CG, Shi S, Graves SA, Hernandez R, Liu B, Theuer CP, Wong HC, Nickles RJ, Cai W.

Clin Cancer Res. 2016 Aug 1;22(15):3821-30. doi: 10.1158/1078-0432.CCR-15-2054. Epub 2016 Mar 29.


Endoglin targeting inhibits tumor angiogenesis and metastatic spread in breast cancer.

Paauwe M, Heijkants RC, Oudt CH, van Pelt GW, Cui C, Theuer CP, Hardwick JC, Sier CF, Hawinkels LJ.

Oncogene. 2016 Aug 4;35(31):4069-79. doi: 10.1038/onc.2015.509. Epub 2016 Jan 25.


High Yield Production and Radiochemical Isolation of Isotopically Pure Arsenic-72 and Novel Radioarsenic Labeling Strategies for the Development of Theranostic Radiopharmaceuticals.

Ellison PA, Barnhart TE, Chen F, Hong H, Zhang Y, Theuer CP, Cai W, Nickles RJ, DeJesus OT.

Bioconjug Chem. 2016 Jan 20;27(1):179-88. doi: 10.1021/acs.bioconjchem.5b00592. Epub 2015 Dec 22.


Noninvasive brain cancer imaging with a bispecific antibody fragment, generated via click chemistry.

Luo H, Hernandez R, Hong H, Graves SA, Yang Y, England CG, Theuer CP, Nickles RJ, Cai W.

Proc Natl Acad Sci U S A. 2015 Oct 13;112(41):12806-11. doi: 10.1073/pnas.1509667112. Epub 2015 Sep 28.


Novel Preparation Methods of (52)Mn for ImmunoPET Imaging.

Graves SA, Hernandez R, Fonslet J, England CG, Valdovinos HF, Ellison PA, Barnhart TE, Elema DR, Theuer CP, Cai W, Nickles RJ, Severin GW.

Bioconjug Chem. 2015 Oct 21;26(10):2118-24. doi: 10.1021/acs.bioconjchem.5b00414. Epub 2015 Sep 10.


PET Imaging of Abdominal Aortic Aneurysm with 64Cu-Labeled Anti-CD105 Antibody Fab Fragment.

Shi S, Orbay H, Yang Y, Graves SA, Nayak TR, Hong H, Hernandez R, Luo H, Goel S, Theuer CP, Nickles RJ, Cai W.

J Nucl Med. 2015 Jun;56(6):927-32. doi: 10.2967/jnumed.114.153098. Epub 2015 Apr 16.


An open-label phase Ib dose-escalation study of TRC105 (anti-endoglin antibody) with bevacizumab in patients with advanced cancer.

Gordon MS, Robert F, Matei D, Mendelson DS, Goldman JW, Chiorean EG, Strother RM, Seon BK, Figg WD, Peer CJ, Alvarez D, Adams BJ, Theuer CP, Rosen LS.

Clin Cancer Res. 2014 Dec 1;20(23):5918-26. doi: 10.1158/1078-0432.CCR-14-1143. Epub 2014 Sep 26.


Engineering of hollow mesoporous silica nanoparticles for remarkably enhanced tumor active targeting efficacy.

Chen F, Hong H, Shi S, Goel S, Valdovinos HF, Hernandez R, Theuer CP, Barnhart TE, Cai W.

Sci Rep. 2014 May 30;4:5080. doi: 10.1038/srep05080.


ENDOGLIN is dispensable for vasculogenesis, but required for vascular endothelial growth factor-induced angiogenesis.

Liu Z, Lebrin F, Maring JA, van den Driesche S, van der Brink S, van Dinther M, Thorikay M, Martin S, Kobayashi K, Hawinkels LJ, van Meeteren LA, Pardali E, Korving J, Letarte M, Arthur HM, Theuer C, Goumans MJ, Mummery C, ten Dijke P.

PLoS One. 2014 Jan 28;9(1):e86273. doi: 10.1371/journal.pone.0086273. eCollection 2014.


Positron emission tomography imaging of CD105 expression in a rat myocardial infarction model with (64)Cu-NOTA-TRC105.

Orbay H, Zhang Y, Valdovinos HF, Song G, Hernandez R, Theuer CP, Hacker TA, Nickles RJ, Cai W.

Am J Nucl Med Mol Imaging. 2013 Dec 15;4(1):1-9. eCollection 2013.


Pravastatin stimulates angiogenesis in a murine hindlimb ischemia model: a positron emission tomography imaging study with (64)Cu-NOTA-TRC105.

Orbay H, Hong H, Koch JM, Valdovinos HF, Hacker TA, Theuer CP, Barnhart TE, Cai W.

Am J Transl Res. 2013 Dec 1;6(1):54-63. eCollection 2013.


Antibody-directed coupling of endoglin and MMP-14 is a key mechanism for endoglin shedding and deregulation of TGF-β signaling.

Kumar S, Pan CC, Bloodworth JC, Nixon AB, Theuer C, Hoyt DG, Lee NY.

Oncogene. 2014 Jul 24;33(30):3970-9. doi: 10.1038/onc.2013.386. Epub 2013 Sep 30.


Image-guided and tumor-targeted drug delivery with radiolabeled unimolecular micelles.

Guo J, Hong H, Chen G, Shi S, Zheng Q, Zhang Y, Theuer CP, Barnhart TE, Cai W, Gong S.

Biomaterials. 2013 Nov;34(33):8323-8332. doi: 10.1016/j.biomaterials.2013.07.085. Epub 2013 Aug 8.


WE-C-217BCD-06: In Vivo Targeting and Imaging of Tumor Vasculature with Radiolabeled, Antibody-Conjugated Nano-Graphene.

Zhang Y, Yang K, Hong H, Engle J, Feng L, Theuer C, Barnhart T, Liu Z, Cai W.

Med Phys. 2012 Jun;39(6Part27):3950. doi: 10.1118/1.4736122.


WE-C-217BCD-04: Multimodality Imaging of Breast Cancer Experimental Lung Metastasis.

Zhang Y, Hong H, Yang Y, Severin G, Engle J, Niu G, Chen X, Leigh B, Barnhart T, Cai W.

Med Phys. 2012 Jun;39(6Part27):3950. doi: 10.1118/1.4736120.


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