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J Am Dent Assoc. 1997 Apr;128 Suppl:31S-36S.

Toxicological considerations of tooth bleaching using peroxide-containing agents.

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Indiana University Schools of Dentistry and Medicine, Indianapolis 46202, USA.


Peroxides have been used for tooth bleaching for more than 100 years. Besides those administered in the dental office, agents for at-home bleaching have become popular. To date, there have been no published significant adverse effects caused by dentist-monitored, at-home bleaching agents. But potential risks, particularly those associated with abuses or the use of inappropriate products, need to be recognized. Using an ADA-accepted, at-home bleaching agent under a dentist's supervision is recommended to minimize risks while achieving desired benefits.

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