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Items: 1 to 20 of 77

1.

In vivo and in situ detection of macromolecular free radicals using immuno-spin trapping and molecular MRI.

Towner R, Smith N.

Antioxid Redox Signal. 2017 Oct 30. doi: 10.1089/ars.2017.7390. [Epub ahead of print]

PMID:
29084431
2.

AG488 as a therapy against gliomas.

Ziegler J, Bastian A, Lerner M, Bailey-Downs L, Saunders D, Smith N, Sutton J, Battiste JD, Ihnat MA, Gangjee A, Towner RA.

Oncotarget. 2017 May 30;8(42):71833-71844. doi: 10.18632/oncotarget.18284. eCollection 2017 Sep 22.

3.

Gestational hypoxia disrupts the neonatal leptin surge and programs hyperphagia and obesity in male offspring in the Sprague-Dawley rat.

Vargas VE, Gurung S, Grant B, Hyatt K, Singleton K, Myers SM, Saunders D, Njoku C, Towner R, Myers DA.

PLoS One. 2017 Sep 28;12(9):e0185272. doi: 10.1371/journal.pone.0185272. eCollection 2017.

4.

Reduced urothelial regeneration in rat bladders augmented with permeable porcine small intestinal submucosa assessed by magnetic resonance imaging.

Yang Q, Xia D, Towner RA, Smith N, Saunders D, Fung KM, Aston CE, Greenwood-Van Meerveld B, Hurst RE, Madihally SV, Kropp BP, Lin HK.

J Biomed Mater Res B Appl Biomater. 2017 Sep 13. doi: 10.1002/jbm.b.33985. [Epub ahead of print]

PMID:
28901710
5.

Profibrotic Infrapatellar Fat Pad Remodeling Without M1 Macrophage Polarization Precedes Knee Osteoarthritis in Mice With Diet-Induced Obesity.

Barboza E, Hudson J, Chang WP, Kovats S, Towner RA, Silasi-Mansat R, Lupu F, Kent C, Griffin TM.

Arthritis Rheumatol. 2017 Jun;69(6):1221-1232. doi: 10.1002/art.40056. Epub 2017 Apr 28.

PMID:
28141918
6.

Role of endoplasmic reticulum stress signalling in diabetic endothelial dysfunction and atherosclerosis.

Dong Y, Fernandes C, Liu Y, Wu Y, Wu H, Brophy ML, Deng L, Song K, Wen A, Wong S, Yan D, Towner R, Chen H.

Diab Vasc Dis Res. 2017 Jan;14(1):14-23. Epub 2016 Oct 20. Review.

PMID:
27941052
7.

ELTD1, an effective anti-angiogenic target for gliomas: preclinical assessment in mouse GL261 and human G55 xenograft glioma models.

Ziegler J, Pody R, Coutinho de Souza P, Evans B, Saunders D, Smith N, Mallory S, Njoku C, Dong Y, Chen H, Dong J, Lerner M, Mian O, Tummala S, Battiste J, Fung KM, Wren JD, Towner RA.

Neuro Oncol. 2017 Feb 1;19(2):175-185. doi: 10.1093/neuonc/now147.

PMID:
27416955
8.

Ameliorative Effects of Antioxidants on the Hippocampal Accumulation of Pathologic Tau in a Rat Model of Blast-Induced Traumatic Brain Injury.

Du X, West MB, Cheng W, Ewert DL, Li W, Saunders D, Towner RA, Floyd RA, Kopke RD.

Oxid Med Cell Longev. 2016;2016:4159357. doi: 10.1155/2016/4159357. Epub 2015 Dec 16.

9.

Motif mimetic of epsin perturbs tumor growth and metastasis.

Dong Y, Wu H, Rahman HN, Liu Y, Pasula S, Tessneer KL, Cai X, Liu X, Chang B, McManus J, Hahn S, Dong J, Brophy ML, Yu L, Song K, Silasi-Mansat R, Saunders D, Njoku C, Song H, Mehta-D'Souza P, Towner R, Lupu F, McEver RP, Xia L, Boerboom D, Srinivasan RS, Chen H.

J Clin Invest. 2016 Apr 1;126(4):1607. doi: 10.1172/JCI87344. Epub 2016 Mar 21. No abstract available.

10.

Safe Oral Triiodo-L-Thyronine Therapy Protects from Post-Infarct Cardiac Dysfunction and Arrhythmias without Cardiovascular Adverse Effects.

Rajagopalan V, Zhang Y, Ojamaa K, Chen YF, Pingitore A, Pol CJ, Saunders D, Balasubramanian K, Towner RA, Gerdes AM.

PLoS One. 2016 Mar 16;11(3):e0151413. doi: 10.1371/journal.pone.0151413. eCollection 2016.

11.

In the absence of overt urothelial damage, chondroitinase ABC digestion of the GAG layer increases bladder permeability in ovariectomized female rats.

Hurst RE, Van Gordon S, Tyler K, Kropp B, Towner R, Lin H, Marentette JO, McHowat J, Mohammedi E, Greenwood-Van Meerveld B.

Am J Physiol Renal Physiol. 2016 May 1;310(10):F1074-80. doi: 10.1152/ajprenal.00566.2015. Epub 2016 Feb 24.

12.

Sexually dimorphic effects of early life stress in rat pups on urinary bladder detrusor muscle contractility in adulthood.

Mohammadi E, Prusator DK, Healing E, Hurst R, Towner RA, Wisniewski AB, Greenwood-Van Meerveld B.

Biol Sex Differ. 2016 Jan 27;7:8. doi: 10.1186/s13293-016-0062-1. eCollection 2016.

13.

Increased bladder permeability in interstitial cystitis/painful bladder syndrome.

Hurst RE, Meerveld BG, Wisniewski AB, VanGordon S, Lin H, Kropp BP, Towner RA.

Transl Androl Urol. 2015 Oct;4(5):563-571.

14.

Targeting mTOR and p53 Signaling Inhibits Muscle Invasive Bladder Cancer In Vivo.

Madka V, Mohammed A, Li Q, Zhang Y, Biddick L, Patlolla JM, Lightfoot S, Towner RA, Wu XR, Steele VE, Kopelovich L, Rao CV.

Cancer Prev Res (Phila). 2016 Jan;9(1):53-62. doi: 10.1158/1940-6207.CAPR-15-0199. Epub 2015 Nov 17.

15.

Motif mimetic of epsin perturbs tumor growth and metastasis.

Dong Y, Wu H, Rahman HN, Liu Y, Pasula S, Tessneer KL, Cai X, Liu X, Chang B, McManus J, Hahn S, Dong J, Brophy ML, Yu L, Song K, Silasi-Mansat R, Saunders D, Njoku C, Song H, Mehta-D'Souza P, Towner R, Lupu F, McEver RP, Xia L, Boerboom D, Srinivasan RS, Chen H.

J Clin Invest. 2015 Dec;125(12):4349-64. doi: 10.1172/JCI80349. Epub 2015 Nov 16. Erratum in: J Clin Invest. 2016 Apr 1;126(4):1607.

16.

A Feasibility Study to Determine Whether Clinical Contrast Enhanced Magnetic Resonance Imaging can Detect Increased Bladder Permeability in Patients with Interstitial Cystitis.

Towner RA, Wisniewski AB, Wu DH, Van Gordon SB, Smith N, North JC, McElhaney R, Aston CE, Shobeiri SA, Kropp BP, Greenwood-Van Meerveld B, Hurst RE.

J Urol. 2016 Mar;195(3):631-8. doi: 10.1016/j.juro.2015.08.077. Epub 2015 Aug 22.

17.

OKN-007 decreases VEGFR-2 levels in a preclinical GL261 mouse glioma model.

de Souza PC, Smith N, Pody R, He T, Njoku C, Silasi-Mansat R, Lupu F, Meek B, Chen H, Dong Y, Saunders D, Orock A, Hodges E, Colijn S, Mamedova N, Towner RA.

Am J Nucl Med Mol Imaging. 2015 Jun 15;5(4):363-78. eCollection 2015.

18.

Inhibition of Pediatric Glioblastoma Tumor Growth by the Anti-Cancer Agent OKN-007 in Orthotopic Mouse Xenografts.

Coutinho de Souza P, Mallory S, Smith N, Saunders D, Li XN, McNall-Knapp RY, Fung KM, Towner RA.

PLoS One. 2015 Aug 6;10(8):e0134276. doi: 10.1371/journal.pone.0134276. eCollection 2015.

19.

A new anti-glioma therapy, AG119: pre-clinical assessment in a mouse GL261 glioma model.

Towner RA, Ihnat M, Saunders D, Bastian A, Smith N, Pavana RK, Gangjee A.

BMC Cancer. 2015 Jul 17;15:522. doi: 10.1186/s12885-015-1538-9.

20.

Pharmacologically-induced neurovascular uncoupling is associated with cognitive impairment in mice.

Tarantini S, Hertelendy P, Tucsek Z, Valcarcel-Ares MN, Smith N, Menyhart A, Farkas E, Hodges EL, Towner R, Deak F, Sonntag WE, Csiszar A, Ungvari Z, Toth P.

J Cereb Blood Flow Metab. 2015 Nov;35(11):1871-81. doi: 10.1038/jcbfm.2015.162. Epub 2015 Jul 15.

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