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Items: 17


Laquinimod arrests experimental autoimmune encephalomyelitis by activating the aryl hydrocarbon receptor.

Kaye J, Piryatinsky V, Birnberg T, Hingaly T, Raymond E, Kashi R, Amit-Romach E, Caballero IS, Towfic F, Ator MA, Rubinstein E, Laifenfeld D, Orbach A, Shinar D, Marantz Y, Grossman I, Knappertz V, Hayden MR, Laufer R.

Proc Natl Acad Sci U S A. 2016 Oct 11;113(41):E6145-E6152.


Pridopidine activates neuroprotective pathways impaired in Huntington Disease.

Geva M, Kusko R, Soares H, Fowler KD, Birnberg T, Barash S, -Wagner AM, Fine T, Lysaght A, Weiner B, Cha Y, Kolitz S, Towfic F, Orbach A, Laufer R, Zeskind B, Grossman I, Hayden MR.

Hum Mol Genet. 2016 Jul 27. pii: ddw238. [Epub ahead of print]


Functional effects of the antigen glatiramer acetate are complex and tightly associated with its composition.

Hasson T, Kolitz S, Towfic F, Laifenfeld D, Bakshi S, Beriozkin O, Shacham-Abramson M, Timan B, Fowler KD, Birnberg T, Konya A, Komlosh A, Ladkani D, Hayden MR, Zeskind B, Grossman I.

J Neuroimmunol. 2016 Jan 15;290:84-95. doi: 10.1016/j.jneuroim.2015.11.020. Epub 2015 Nov 24.


Leveraging existing data sets to generate new insights into Alzheimer's disease biology in specific patient subsets.

Fowler KD, Funt JM, Artyomov MN, Zeskind B, Kolitz SE, Towfic F.

Sci Rep. 2015 Sep 23;5:14324. doi: 10.1038/srep14324.


Gene expression studies of a human monocyte cell line identify dissimilarities between differently manufactured glatiramoids.

Kolitz S, Hasson T, Towfic F, Funt JM, Bakshi S, Fowler KD, Laifenfeld D, Grinspan A, Artyomov MN, Birnberg T, Schwartz R, Komlosh A, Hayardeny L, Ladkani D, Hayden MR, Zeskind B, Grossman I.

Sci Rep. 2015 May 22;5:10191. doi: 10.1038/srep10191.


Use of genetic technologies to compare medicines.

Kolitz SE, Towfic F, Grossman I, Hayden MR, Zeskind B.

Clin Genet. 2014 Nov;86(5):441-6. doi: 10.1111/cge.12462. Epub 2014 Sep 8. Review.


Comparing the biological impact of glatiramer acetate with the biological impact of a generic.

Towfic F, Funt JM, Fowler KD, Bakshi S, Blaugrund E, Artyomov MN, Hayden MR, Ladkani D, Schwartz R, Zeskind B.

PLoS One. 2014 Jan 8;9(1):e83757. doi: 10.1371/journal.pone.0083757. eCollection 2014.


Genetic variants synthesize to produce paneth cell phenotypes that define subtypes of Crohn's disease.

VanDussen KL, Liu TC, Li D, Towfic F, Modiano N, Winter R, Haritunians T, Taylor KD, Dhall D, Targan SR, Xavier RJ, McGovern DP, Stappenbeck TS.

Gastroenterology. 2014 Jan;146(1):200-9. doi: 10.1053/j.gastro.2013.09.048. Epub 2013 Sep 25.


Defining the transcriptional and cellular landscape of type 1 diabetes in the NOD mouse.

Carrero JA, Calderon B, Towfic F, Artyomov MN, Unanue ER.

PLoS One. 2013;8(3):e59701. doi: 10.1371/journal.pone.0059701. Epub 2013 Mar 26. Erratum in: PLoS One. 2014;9(1). doi:10.1371/annotation/f277b29e-361b-4e56-b55b-612ebaca0432.


B-cell ligand processing pathways detected by large-scale comparative analysis.

Towfic F, Gupta S, Honavar V, Subramaniam S.

Genomics Proteomics Bioinformatics. 2012 Jun;10(3):142-52. doi: 10.1016/j.gpb.2012.03.001. Epub 2012 Jun 25.


Protein-RNA interface residue prediction using machine learning: an assessment of the state of the art.

Walia RR, Caragea C, Lewis BA, Towfic F, Terribilini M, El-Manzalawy Y, Dobbs D, Honavar V.

BMC Bioinformatics. 2012 May 10;13:89. doi: 10.1186/1471-2105-13-89.


Genome-wide siRNA screen for mediators of NF-κB activation.

Gewurz BE, Towfic F, Mar JC, Shinners NP, Takasaki K, Zhao B, Cahir-McFarland ED, Quackenbush J, Xavier RJ, Kieff E.

Proc Natl Acad Sci U S A. 2012 Feb 14;109(7):2467-72. doi: 10.1073/pnas.1120542109. Epub 2012 Jan 17.


Exploration of the relationship between topology and designability of conformations.

Leelananda SP, Towfic F, Jernigan RL, Kloczkowski A.

J Chem Phys. 2011 Jun 21;134(23):235101. doi: 10.1063/1.3596947.


Shape-based feature matching improves protein identification via LC-MS and tandem MS.

Noy K, Towfic F, Wittenberg GM, Fasulo D.

J Comput Biol. 2011 Apr;18(4):547-57. doi: 10.1089/cmb.2010.0155. Epub 2011 Mar 21.


Detection of gene orthology from gene co-expression and protein interaction networks.

Towfic F, VanderPlas S, Oliver CA, Couture O, Tuggle CK, West Greenlee MH, Honavar V.

BMC Bioinformatics. 2010 Apr 29;11 Suppl 3:S7. doi: 10.1186/1471-2105-11-S3-S7.


Struct-NB: predicting protein-RNA binding sites using structural features.

Towfic F, Caragea C, Gemperline DC, Dobbs D, Honavar V.

Int J Data Min Bioinform. 2010;4(1):21-43.


Short paths in protein structure space originate in graph structure.

Zimmermann M, Towfic F, Jernigan RL, Kloczkowski A.

Proc Natl Acad Sci U S A. 2009 Dec 22;106(51):E137; author reply E138. doi: 10.1073/pnas.0912339106. Epub 2009 Dec 14. No abstract available.

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