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Items: 1 to 20 of 202


Iron and cancer: recent insights.

Manz DH, Blanchette NL, Paul BT, Torti FM, Torti SV.

Ann N Y Acad Sci. 2016 Mar;1368(1):149-61. doi: 10.1111/nyas.13008. Epub 2016 Feb 18.


Modulation of hepcidin to treat iron deregulation: potential clinical applications.

Blanchette NL, Manz DH, Torti FM, Torti SV.

Expert Rev Hematol. 2016;9(2):169-86. doi: 10.1586/17474086.2016.1124757. Epub 2015 Dec 15.


Cytoprotective Effect of Ferritin H in Renal Ischemia Reperfusion Injury.

Hatcher HC, Tesfay L, Torti SV, Torti FM.

PLoS One. 2015 Sep 17;10(9):e0138505. doi: 10.1371/journal.pone.0138505. eCollection 2015.


Hepcidin regulation in prostate and its disruption in prostate cancer.

Tesfay L, Clausen KA, Kim JW, Hegde P, Wang X, Miller LD, Deng Z, Blanchette N, Arvedson T, Miranti CK, Babitt JL, Lin HY, Peehl DM, Torti FM, Torti SV.

Cancer Res. 2015 Jun 1;75(11):2254-63. doi: 10.1158/0008-5472.CAN-14-2465. Epub 2015 Apr 9.


Yet another function of p53--the switch that determines whether radiation-induced autophagy will be cytoprotective or nonprotective: implications for autophagy inhibition as a therapeutic strategy.

Chakradeo S, Sharma K, Alhaddad A, Bakhshwin D, Le N, Harada H, Nakajima W, Yeudall WA, Torti SV, Torti FM, Gewirtz DA.

Mol Pharmacol. 2015 May;87(5):803-14. doi: 10.1124/mol.114.095273. Epub 2015 Feb 9.


A novel cytostatic form of autophagy in sensitization of non-small cell lung cancer cells to radiation by vitamin D and the vitamin D analog, EB 1089.

Sharma K, Goehe RW, Di X, Hicks MA 2nd, Torti SV, Torti FM, Harada H, Gewirtz DA.

Autophagy. 2014;10(12):2346-61. doi: 10.4161/15548627.2014.993283.


Epidemiological associations between iron and cardiovascular disease and diabetes.

Basuli D, Stevens RG, Torti FM, Torti SV.

Front Pharmacol. 2014 May 20;5:117. doi: 10.3389/fphar.2014.00117. eCollection 2014. Review.


The high-molecular-weight kininogen domain 5 is an intrinsically unstructured protein and its interaction with ferritin is metal mediated.

Huhn AJ, Parsonage D, Horita DA, Torti FM, Torti SV, Hollis T.

Protein Sci. 2014 Aug;23(8):1013-22. doi: 10.1002/pro.2486. Epub 2014 May 22.


IRP2 regulates breast tumor growth.

Wang W, Deng Z, Hatcher H, Miller LD, Di X, Tesfay L, Sui G, D'Agostino RB Jr, Torti FM, Torti SV.

Cancer Res. 2014 Jan 15;74(2):497-507. doi: 10.1158/0008-5472.CAN-13-1224. Epub 2013 Nov 27.


The new University of Connecticut Health Center.

Torti FM.

Conn Med. 2013 Aug;77(7):431-2. No abstract available.


Cellular iron metabolism in prognosis and therapy of breast cancer.

Torti SV, Torti FM.

Crit Rev Oncog. 2013;18(5):435-48. Review.


Application of circuit simulation method for differential modeling of TIM-2 iron uptake and metabolism in mouse kidney cells.

Xie Z, Harrison SH, Torti SV, Torti FM, Han J.

Front Physiol. 2013 Jun 7;4:136. doi: 10.3389/fphys.2013.00136. eCollection 2013.


Low to moderate dose anthracycline-based chemotherapy is associated with early noninvasive imaging evidence of subclinical cardiovascular disease.

Drafts BC, Twomley KM, D'Agostino R Jr, Lawrence J, Avis N, Ellis LR, Thohan V, Jordan J, Melin SA, Torti FM, Little WC, Hamilton CA, Hundley WG.

JACC Cardiovasc Imaging. 2013 Aug;6(8):877-85. doi: 10.1016/j.jcmg.2012.11.017. Epub 2013 May 1.


Ferritin H is a novel marker of early erythroid precursors and macrophages.

Wang W, Grier DD, Woo J, Ward M, Sui G, Torti SV, Torti FM, Beaty MW.

Histopathology. 2013 May;62(6):931-40. doi: 10.1111/his.12101.


Iron and cancer: more ore to be mined.

Torti SV, Torti FM.

Nat Rev Cancer. 2013 May;13(5):342-55. doi: 10.1038/nrc3495. Epub 2013 Apr 18. Review.


Weekly doxorubicin increases coronary arteriolar wall and adventitial thickness.

Eckman DM, Stacey RB, Rowe R, D'Agostino R Jr, Kock ND, Sane DC, Torti FM, Yeboah J, Workman S, Lane KS, Hundley WG.

PLoS One. 2013;8(2):e57554. doi: 10.1371/journal.pone.0057554. Epub 2013 Feb 21.


Heat localization for targeted tumor treatment with nanoscale near-infrared radiation absorbers.

Xie B, Singh R, Torti FM, Keblinski P, Torti S.

Phys Med Biol. 2012 Sep 21;57(18):5765-75. doi: 10.1088/0031-9155/57/18/5765. Epub 2012 Sep 5.


Ferritin blocks inhibitory effects of two-chain high molecular weight kininogen (HKa) on adhesion and survival signaling in endothelial cells.

Tesfay L, Huhn AJ, Hatcher H, Torti FM, Torti SV.

PLoS One. 2012;7(7):e40030. doi: 10.1371/journal.pone.0040030. Epub 2012 Jul 2.


Targeting Cancer Stem Cells with Nanoparticle-Enabled Therapies.

Burke AR, Singh RN, Carroll DL, Torti FM, Torti SV.

J Mol Biomark Diagn. 2012 Jul 2;Suppl 8. doi: 10.4172/2155-9929.S8-003.


Potential impact of adding genetic markers to clinical parameters in predicting prostate biopsy outcomes in men following an initial negative biopsy: findings from the REDUCE trial.

Kader AK, Sun J, Reck BH, Newcombe PJ, Kim ST, Hsu FC, D'Agostino RB Jr, Tao S, Zhang Z, Turner AR, Platek GT, Spraggs CF, Whittaker JC, Lane BR, Isaacs WB, Meyers DA, Bleecker ER, Torti FM, Trent JM, McConnell JD, Zheng SL, Condreay LD, Rittmaster RS, Xu J.

Eur Urol. 2012 Dec;62(6):953-61. doi: 10.1016/j.eururo.2012.05.006. Epub 2012 May 12.

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