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Items: 20

1.

Activation of proteinase 3 contributes to Non-alcoholic Fatty Liver Disease (NAFLD) and insulin resistance.

Toonen EJ, Mirea AM, Tack CJ, Stienstra R, Ballak DB, van Diepen JA, Hijmans A, Chavakis T, Dokter WH, Pham CT, Netea MG, Dinarello CA, Joosten LA.

Mol Med. 2016 May 24;22. doi: 10.2119/molmed.2016.00033.

2.

Glucose kinetics in the collagen-induced arthritis model: an all-in-one model to assess both efficacy and metabolic side effects of glucocorticoids.

Toonen EJ, Laskewitz AJ, van Dijk TH, Bleeker A, Grefhorst A, Schouten AE, Bastiaanssen EA, Ballak DB, Koenders MI, van Doorn C, van der Vleuten MA, van Lierop MJ, Groen AK, Dokter WH.

PLoS One. 2014 Sep 2;9(9):e98684. doi: 10.1371/journal.pone.0098684.

3.

Identification of gene signatures for prednisolone-induced metabolic dysfunction in collagen-induced arthritic mice.

Ellero-Simatos S, Fleuren WW, Bauerschmidt S, Dokter WH, Toonen EJ.

Pharmacogenomics. 2014 Apr;15(5):629-41. doi: 10.2217/pgs.14.3.

PMID:
24798720
4.

Prednisolone induces the Wnt signalling pathway in 3T3-L1 adipocytes.

Fleuren WW, Linssen MM, Toonen EJ, van der Zon GC, Guigas B, de Vlieg J, Dokter WH, Ouwens DM, Alkema W.

Arch Physiol Biochem. 2013 May;119(2):52-64. doi: 10.3109/13813455.2013.774022.

5.

Identification of new biomarker candidates for glucocorticoid induced insulin resistance using literature mining.

Fleuren WW, Toonen EJ, Verhoeven S, Frijters R, Hulsen T, Rullmann T, van Schaik R, de Vlieg J, Alkema W.

BioData Min. 2013 Feb 4;6(1):2. doi: 10.1186/1756-0381-6-2.

6.

Genome-wide association analysis of anti-TNF drug response in patients with rheumatoid arthritis.

Umiċeviċ Mirkov M, Cui J, Vermeulen SH, Stahl EA, Toonen EJ, Makkinje RR, Lee AT, Huizinga TW, Allaart R, Barton A, Mariette X, Miceli CR, Criswell LA, Tak PP, de Vries N, Saevarsdottir S, Padyukov L, Bridges SL, van Schaardenburg DJ, Jansen TL, Dutmer EA, van de Laar MA, Barrera P, Radstake TR, van Riel PL, Scheffer H, Franke B, Brunner HG, Plenge RM, Gregersen PK, Guchelaar HJ, Coenen MJ.

Ann Rheum Dis. 2013 Aug;72(8):1375-81. doi: 10.1136/annrheumdis-2012-202405.

7.

Meta-analysis identified the TNFA -308G > A promoter polymorphism as a risk factor for disease severity in patients with rheumatoid arthritis.

Toonen EJ, Barrera P, Fransen J, de Brouwer AP, Eijsbouts AM, Miossec P, Marotte H, Scheffer H, van Riel PL, Franke B, Coenen MJ.

Arthritis Res Ther. 2012 Dec 7;14(6):R264. doi: 10.1186/ar4110.

8.

Validation study of existing gene expression signatures for anti-TNF treatment in patients with rheumatoid arthritis.

Toonen EJ, Gilissen C, Franke B, Kievit W, Eijsbouts AM, den Broeder AA, van Reijmersdal SV, Veltman JA, Scheffer H, Radstake TR, van Riel PL, Barrera P, Coenen MJ.

PLoS One. 2012;7(3):e33199. doi: 10.1371/journal.pone.0033199.

9.

Prednisolone-induced beta cell dysfunction is associated with impaired endoplasmic reticulum homeostasis in INS-1E cells.

Linssen MM, van Raalte DH, Toonen EJ, Alkema W, van der Zon GC, Dokter WH, Diamant M, Guigas B, Ouwens DM.

Cell Signal. 2011 Nov;23(11):1708-15. doi: 10.1016/j.cellsig.2011.06.002.

PMID:
21689745
10.

Prednisolone-induced changes in gene-expression profiles in healthy volunteers.

Toonen EJ, Fleuren WW, Nässander U, van Lierop MJ, Bauerschmidt S, Dokter WH, Alkema W.

Pharmacogenomics. 2011 Jul;12(7):985-98. doi: 10.2217/pgs.11.34.

PMID:
21635145
11.

Genetic variants in toll-like receptors are not associated with rheumatoid arthritis susceptibility or anti-tumour necrosis factor treatment outcome.

Coenen MJ, Enevold C, Barrera P, Schijvenaars MM, Toonen EJ, Scheffer H, Padyukov L, Kastbom A, Klareskog L, Barton A, Kievit W, Rood MJ, Jansen TL, Swinkels D, van Riel PL, Franke B, Bendtzen K, Radstake TR.

PLoS One. 2010 Dec 15;5(12):e14326. doi: 10.1371/journal.pone.0014326.

12.

Prednisolone-induced differential gene expression in mouse liver carrying wild type or a dimerization-defective glucocorticoid receptor.

Frijters R, Fleuren W, Toonen EJ, Tuckermann JP, Reichardt HM, van der Maaden H, van Elsas A, van Lierop MJ, Dokter W, de Vlieg J, Alkema W.

BMC Genomics. 2010 Jun 5;11:359. doi: 10.1186/1471-2164-11-359.

13.

Multiplex screening of 22 single-nucleotide polymorphisms in 7 Toll-like receptors: an association study in rheumatoid arthritis.

Enevold C, Radstake TR, Coenen MJ, Fransen J, Toonen EJ, Bendtzen K, van Riel PL.

J Rheumatol. 2010 May;37(5):905-10. doi: 10.3899/jrheum.090775.

PMID:
20194452
14.

Tumour necrosis factor alpha -308G->A polymorphism is not associated with response to TNFalpha blockers in Caucasian patients with rheumatoid arthritis: systematic review and meta-analysis.

Pavy S, Toonen EJ, Miceli-Richard C, Barrera P, van Riel PL, Criswell LA, Mariette X, Coenen MJ.

Ann Rheum Dis. 2010 Jun;69(6):1022-8. doi: 10.1136/ard.2009.117622. Review.

PMID:
19966089
15.

HMOX1 promoter polymorphism modulates the relationship between disease activity and joint damage in rheumatoid arthritis.

Wagener FA, Toonen EJ, Wigman L, Fransen J, Creemers MC, Radstake TR, Coenen MJ, Barrera P, van Riel PL, Russel FG.

Arthritis Rheum. 2008 Nov;58(11):3388-93. doi: 10.1002/art.23970.

16.

The tumour necrosis factor receptor superfamily member 1b 676T>G polymorphism in relation to response to infliximab and adalimumab treatment and disease severity in rheumatoid arthritis.

Toonen EJ, Coenen MJ, Kievit W, Fransen J, Eijsbouts AM, Scheffer H, Radstake TR, Creemers MC, de Rooij DJ, van Riel PL, Franke B, Barrera P.

Ann Rheum Dis. 2008 Aug;67(8):1174-7. doi: 10.1136/ard.2008.088138.

PMID:
18385279
17.

The functional variant (Asp299gly) of toll-like receptor 4 (TLR4) influences TLR4-mediated cytokine production in rheumatoid arthritis.

Roelofs MF, Wenink MH, Toonen EJ, Coenen MJ, Joosten LA, van den Berg WB, van Riel PL, Radstake TR.

J Rheumatol. 2008 Apr;35(4):558-61.

PMID:
18381796
18.

Gene expression profiling in rheumatoid arthritis: current concepts and future directions.

Toonen EJ, Barrera P, Radstake TR, van Riel PL, Scheffer H, Franke B, Coenen MJ.

Ann Rheum Dis. 2008 Dec;67(12):1663-9. doi: 10.1136/ard.2007.076588. Review.

PMID:
18250114
19.

Pharmacogenetics of anti-TNF treatment in patients with rheumatoid arthritis.

Coenen MJ, Toonen EJ, Scheffer H, Radstake TR, Barrera P, Franke B.

Pharmacogenomics. 2007 Jul;8(7):761-73.

PMID:
17638513
20.

Macrophage migration inhibitory factor polymorphisms do not predict therapeutic response to glucocorticoids or to tumour necrosis factor alpha-neutralising treatments in rheumatoid arthritis.

Radstake TR, Fransen J, Toonen EJ, Coenen MJ, Eijsbouts AE, Donn R, van den Hoogen FH, van Riel PL.

Ann Rheum Dis. 2007 Nov;66(11):1525-30.

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