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Items: 1 to 20 of 62

1.

Transcriptomic and proteomic insight into the effects of a defined European mistletoe extract in Ewing sarcoma cells reveals cellular stress responses.

Twardziok M, Meierhofer D, Börno S, Timmermann B, Jäger S, Boral S, Eggert A, Delebinski CI, Seifert G.

BMC Complement Altern Med. 2017 Apr 28;17(1):237. doi: 10.1186/s12906-017-1715-2.

2.

QSEA-modelling of genome-wide DNA methylation from sequencing enrichment experiments.

Lienhard M, Grasse S, Rolff J, Frese S, Schirmer U, Becker M, Börno S, Timmermann B, Chavez L, Sültmann H, Leschber G, Fichtner I, Schweiger MR, Herwig R.

Nucleic Acids Res. 2017 Apr 7;45(6):e44. doi: 10.1093/nar/gkw1193.

3.

The metabolic background is a global player in Saccharomyces gene expression epistasis.

Alam MT, Zelezniak A, Mülleder M, Shliaha P, Schwarz R, Capuano F, Vowinckel J, Radmaneshfar E, Krüger A, Calvani E, Michel S, Börno S, Christen S, Patil KR, Timmermann B, Lilley KS, Ralser M.

Nat Microbiol. 2016 Feb 1;1:15030. doi: 10.1038/nmicrobiol.2015.30.

4.

The bromodomain protein BRD4 regulates splicing during heat shock.

Hussong M, Kaehler C, Kerick M, Grimm C, Franz A, Timmermann B, Welzel F, Isensee J, Hucho T, Krobitsch S, Schweiger MR.

Nucleic Acids Res. 2017 Jan 9;45(1):382-394. doi: 10.1093/nar/gkw729. Epub 2016 Aug 17.

5.

Improved 6-year overall survival in AT/RT - results of the registry study Rhabdoid 2007.

Bartelheim K, Nemes K, Seeringer A, Kerl K, Buechner J, Boos J, Graf N, Dürken M, Gerss J, Hasselblatt M, Kortmann RD, Teichert von Luettichau I, Nagel I, Nygaard R, Oyen F, Quiroga E, Schlegel PG, Schmid I, Schneppenheim R, Siebert R, Solano-Paez P, Timmermann B, Warmuth-Metz M, Frühwald MC.

Cancer Med. 2016 Aug;5(8):1765-75. doi: 10.1002/cam4.741. Epub 2016 May 26.

6.

Combined ultra-low input mRNA and whole-genome sequencing of human embryonic stem cells.

Mertes F, Lichtner B, Kuhl H, Blattner M, Otte J, Wruck W, Timmermann B, Lehrach H, Adjaye J.

BMC Genomics. 2015 Nov 12;16:925. doi: 10.1186/s12864-015-2025-z.

7.

Novel HSP90 inhibitors effectively target functions of thyroid cancer stem cell preventing migration and invasion.

White PT, Subramanian C, Zhu Q, Zhang H, Zhao H, Gallagher R, Timmermann BN, Blagg BS, Cohen MS.

Surgery. 2016 Jan;159(1):142-51. doi: 10.1016/j.surg.2015.07.050. Epub 2015 Nov 2.

8.

Allele frequencies of BRAFV600 mutations in primary melanomas and matched metastases and their relevance for BRAF inhibitor therapy in metastatic melanoma.

Satzger I, Marks L, Kerick M, Klages S, Berking C, Herbst R, Völker B, Schacht V, Timmermann B, Gutzmer R.

Oncotarget. 2015 Nov 10;6(35):37895-905. doi: 10.18632/oncotarget.5634.

9.

Disruptions of topological chromatin domains cause pathogenic rewiring of gene-enhancer interactions.

Lupiáñez DG, Kraft K, Heinrich V, Krawitz P, Brancati F, Klopocki E, Horn D, Kayserili H, Opitz JM, Laxova R, Santos-Simarro F, Gilbert-Dussardier B, Wittler L, Borschiwer M, Haas SA, Osterwalder M, Franke M, Timmermann B, Hecht J, Spielmann M, Visel A, Mundlos S.

Cell. 2015 May 21;161(5):1012-25. doi: 10.1016/j.cell.2015.04.004. Epub 2015 May 7.

10.

Using the canary genome to decipher the evolution of hormone-sensitive gene regulation in seasonal singing birds.

Frankl-Vilches C, Kuhl H, Werber M, Klages S, Kerick M, Bakker A, de Oliveira EH, Reusch C, Capuano F, Vowinckel J, Leitner S, Ralser M, Timmermann B, Gahr M.

Genome Biol. 2015 Jan 29;16:19. doi: 10.1186/s13059-014-0578-9.

11.

The CatSper channel controls chemosensation in sea urchin sperm.

Seifert R, Flick M, Bönigk W, Alvarez L, Trötschel C, Poetsch A, Müller A, Goodwin N, Pelzer P, Kashikar ND, Kremmer E, Jikeli J, Timmermann B, Kuhl H, Fridman D, Windler F, Kaupp UB, Strünker T.

EMBO J. 2015 Feb 3;34(3):379-92. doi: 10.15252/embj.201489376. Epub 2014 Dec 22.

12.

Analysis of Major Withanolides in Physalis longifolia Nutt. by HPLC-PDA.

Cao CM, Kindscher K, Gallagher RJ, Zhang H, Timmermann BN.

J Chromatogr Sci. 2015 Aug;53(7):1044-7. doi: 10.1093/chromsci/bmu162. Epub 2014 Dec 2.

13.

Screening for single nucleotide variants, small indels and exon deletions with a next-generation sequencing based gene panel approach for Usher syndrome.

Krawitz PM, Schiska D, Krüger U, Appelt S, Heinrich V, Parkhomchuk D, Timmermann B, Millan JM, Robinson PN, Mundlos S, Hecht J, Gross M.

Mol Genet Genomic Med. 2014 Sep;2(5):393-401. doi: 10.1002/mgg3.92. Epub 2014 Jun 15.

14.

Antiproliferative withanolides from several solanaceous species.

Zhang H, Cao CM, Gallagher RJ, Timmermann BN.

Nat Prod Res. 2014;28(22):1941-51. doi: 10.1080/14786419.2014.919286. Epub 2014 May 28. Review.

15.

The bromodomain protein BRD4 regulates the KEAP1/NRF2-dependent oxidative stress response.

Hussong M, Börno ST, Kerick M, Wunderlich A, Franz A, Sültmann H, Timmermann B, Lehrach H, Hirsch-Kauffmann M, Schweiger MR.

Cell Death Dis. 2014 Apr 24;5:e1195. doi: 10.1038/cddis.2014.157.

16.

Oxidative cytotoxic agent withaferin A resensitizes temozolomide-resistant glioblastomas via MGMT depletion and induces apoptosis through Akt/mTOR pathway inhibitory modulation.

Grogan PT, Sarkaria JN, Timmermann BN, Cohen MS.

Invest New Drugs. 2014 Aug;32(4):604-17. doi: 10.1007/s10637-014-0084-7. Epub 2014 Apr 10.

17.

Withanolides from Jaborosa caulescens var. bipinnatifida.

Zhang H, Cao CM, Gallagher RJ, Day VW, Montenegro G, Timmermann BN.

Phytochemistry. 2014 Feb;98:232-5. doi: 10.1016/j.phytochem.2013.11.005. Epub 2013 Dec 5.

18.

Synthesis and Cytotoxicity of Semisynthetic Withalongolide A Analogues.

Motiwala HF, Bazzill J, Samadi A, Zhang H, Timmermann BN, Cohen MS, Aubé J.

ACS Med Chem Lett. 2013 Nov 14;4(11). doi: 10.1021/ml400267q.

19.

Distinct global shifts in genomic binding profiles of limb malformation-associated HOXD13 mutations.

Ibrahim DM, Hansen P, Rödelsperger C, Stiege AC, Doelken SC, Horn D, Jäger M, Janetzki C, Krawitz P, Leschik G, Wagner F, Scheuer T, Schmidt-von Kegler M, Seemann P, Timmermann B, Robinson PN, Mundlos S, Hecht J.

Genome Res. 2013 Dec;23(12):2091-102. doi: 10.1101/gr.157610.113. Epub 2013 Aug 30.

20.

High-throughput miRNA and mRNA sequencing of paired colorectal normal, tumor and metastasis tissues and bioinformatic modeling of miRNA-1 therapeutic applications.

Röhr C, Kerick M, Fischer A, Kühn A, Kashofer K, Timmermann B, Daskalaki A, Meinel T, Drichel D, Börno ST, Nowka A, Krobitsch S, McHardy AC, Kratsch C, Becker T, Wunderlich A, Barmeyer C, Viertler C, Zatloukal K, Wierling C, Lehrach H, Schweiger MR.

PLoS One. 2013 Jul 2;8(7):e67461. doi: 10.1371/journal.pone.0067461. Print 2013.

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