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FDA Approval: Ribociclib for the Treatment of Postmenopausal Women with Hormone Receptor-Positive, HER2-Negative Advanced or Metastatic Breast Cancer.

Shah A, Bloomquist E, Tang S, Fu W, Bi Y, Liu Q, Yu J, Zhao P, Palmby TR, Goldberg KB, Chang CJG, Patel P, Alebachew E, Tilley A, Pierce WF, Ibrahim A, Blumenthal GM, Sridhara R, Beaver JA, Pazdur R.

Clin Cancer Res. 2018 Feb 7. pii: clincanres.2369.2017. doi: 10.1158/1078-0432.CCR-17-2369. [Epub ahead of print]


A global perspective on the trophic geography of sharks.

Bird CS, Veríssimo A, Magozzi S, Abrantes KG, Aguilar A, Al-Reasi H, Barnett A, Bethea DM, Biais G, Borrell A, Bouchoucha M, Boyle M, Brooks EJ, Brunnschweiler J, Bustamante P, Carlisle A, Catarino D, Caut S, Cherel Y, Chouvelon T, Churchill D, Ciancio J, Claes J, Colaço A, Courtney DL, Cresson P, Daly R, de Necker L, Endo T, Figueiredo I, Frisch AJ, Hansen JH, Heithaus M, Hussey NE, Iitembu J, Juanes F, Kinney MJ, Kiszka JJ, Klarian SA, Kopp D, Leaf R, Li Y, Lorrain A, Madigan DJ, Maljković A, Malpica-Cruz L, Matich P, Meekan MG, Ménard F, Menezes GM, Munroe SEM, Newman MC, Papastamatiou YP, Pethybridge H, Plumlee JD, Polo-Silva C, Quaeck-Davies K, Raoult V, Reum J, Torres-Rojas YE, Shiffman DS, Shipley ON, Speed CW, Staudinger MD, Teffer AK, Tilley A, Valls M, Vaudo JJ, Wai TC, Wells RJD, Wyatt ASJ, Yool A, Trueman CN.

Nat Ecol Evol. 2018 Feb;2(2):299-305. doi: 10.1038/s41559-017-0432-z. Epub 2018 Jan 18.


Microwave Synthesis of Thionated Naphthalene Diimide-Based Small Molecules and Polymers.

Pahlavanlu P, Tilley AJ, McAllister BT, Seferos DS.

J Org Chem. 2017 Dec 1;82(23):12337-12345. doi: 10.1021/acs.joc.7b02162. Epub 2017 Oct 26.


Three-Dimensional Arylene Diimide Frameworks for Highly Stable Lithium Ion Batteries.

Schon TB, Tilley AJ, Kynaston EL, Seferos DS.

ACS Appl Mater Interfaces. 2017 May 10;9(18):15631-15637. doi: 10.1021/acsami.7b02336. Epub 2017 May 2.


A Study of Boratriazaroles: An Underdeveloped Class of Heterocycles.

Liew SK, Holownia A, Tilley AJ, Carrera EI, Seferos DS, Yudin AK.

J Org Chem. 2016 Nov 4;81(21):10444-10453. Epub 2016 Sep 12.


Persistence of circulating endothelial microparticles in COPD despite smoking cessation.

Strulovici-Barel Y, Staudt MR, Krause A, Gordon C, Tilley AE, Harvey BG, Kaner RJ, Hollmann C, Mezey JG, Bitter H, Pillai SG, Hilton H, Wolff G, Stevenson CS, Visvanathan S, Fine JS, Crystal RG.

Thorax. 2016 Dec;71(12):1137-1144. doi: 10.1136/thoraxjnl-2015-208274. Epub 2016 Jul 26.


FDA Approval of Palbociclib in Combination with Fulvestrant for the Treatment of Hormone Receptor-Positive, HER2-Negative Metastatic Breast Cancer.

Walker AJ, Wedam S, Amiri-Kordestani L, Bloomquist E, Tang S, Sridhara R, Chen W, Palmby TR, Fourie Zirkelbach J, Fu W, Liu Q, Tilley A, Kim G, Kluetz PG, McKee AE, Pazdur R.

Clin Cancer Res. 2016 Oct 15;22(20):4968-4972. Epub 2016 Jul 12.


Observation of Two Triplet-Pair Intermediates in Singlet Exciton Fission.

Pensack RD, Ostroumov EE, Tilley AJ, Mazza S, Grieco C, Thorley KJ, Asbury JB, Seferos DS, Anthony JE, Scholes GD.

J Phys Chem Lett. 2016 Jul 7;7(13):2370-5. doi: 10.1021/acs.jpclett.6b00947. Epub 2016 Jun 13.


A longitudinal analysis of chronic arm morbidity following breast cancer surgery.

Boquiren VM, Hack TF, Thomas RL, Towers A, Kwan WB, Tilley A, Quinlan E, Miedema B.

Breast Cancer Res Treat. 2016 Jun;157(3):413-25. doi: 10.1007/s10549-016-3834-8. Epub 2016 May 18.


Cigarette Smoking Induces Changes in Airway Epithelial Expression of Genes Associated with Monogenic Lung Disorders.

Tilley AE, Staudt MR, Salit J, Van de Graaf B, Strulovici-Barel Y, Kaner RJ, Vincent T, Agosto-Perez F, Mezey JG, Raby BA, Crystal RG.

Am J Respir Crit Care Med. 2016 Jan 15;193(2):215-7. doi: 10.1164/rccm.201412-2290LE. No abstract available.


Loss, adaptation and new directions: The impact of arm morbidity on leisure activities following breast cancer.

Thomas R, Hack TF, Quinlan E, Tatemichi S, Towers A, Kwan W, Miedema B, Tilley A, Hamoline R, Morrison T.

Can Oncol Nurs J. 2015 Winter;25(1):49-59. English, French.


Correlations of plasma renin activity and aldosterone concentration with ambulatory blood pressure responses to nebivolol and valsartan, alone and in combination, in hypertension.

Giles TD, Bakris G, Oparil S, Weber MA, Li H, Mallick M, Bharucha DB, Chen C, Ferguson WG; NAC-MD-01 Substudy Investigators.

J Am Soc Hypertens. 2015 Nov;9(11):845-54. doi: 10.1016/j.jash.2015.08.003. Epub 2015 Aug 12.


FDA Approval: Palbociclib for the Treatment of Postmenopausal Patients with Estrogen Receptor-Positive, HER2-Negative Metastatic Breast Cancer.

Beaver JA, Amiri-Kordestani L, Charlab R, Chen W, Palmby T, Tilley A, Zirkelbach JF, Yu J, Liu Q, Zhao L, Crich J, Chen XH, Hughes M, Bloomquist E, Tang S, Sridhara R, Kluetz PG, Kim G, Ibrahim A, Pazdur R, Cortazar P.

Clin Cancer Res. 2015 Nov 1;21(21):4760-6. doi: 10.1158/1078-0432.CCR-15-1185. Epub 2015 Aug 31. Review.


Exciton delocalization drives rapid singlet fission in nanoparticles of acene derivatives.

Pensack RD, Tilley AJ, Parkin SR, Lee TS, Payne MM, Gao D, Jahnke AA, Oblinsky DG, Li PF, Anthony JE, Seferos DS, Scholes GD.

J Am Chem Soc. 2015 Jun 3;137(21):6790-803. doi: 10.1021/ja512668r. Epub 2015 May 18.


Persistence of smoking-induced dysregulation of miRNA expression in the small airway epithelium despite smoking cessation.

Wang G, Wang R, Strulovici-Barel Y, Salit J, Staudt MR, Ahmed J, Tilley AE, Yee-Levin J, Hollmann C, Harvey BG, Kaner RJ, Mezey JG, Sridhar S, Pillai SG, Hilton H, Wolff G, Bitter H, Visvanathan S, Fine JS, Stevenson CS, Crystal RG.

PLoS One. 2015 Apr 17;10(4):e0120824. doi: 10.1371/journal.pone.0120824. eCollection 2015.


Excited state dynamics of organic semi-conducting materials.

Ghiggino KP, Tilley AJ, Robotham B, White JM.

Faraday Discuss. 2015;177:111-9. doi: 10.1039/c4fd00171k.


Synthesis and photophysical properties of platinum-acetylide copolymers with thiophene, selenophene and tellurophene.

Mahrok AK, Carrera EI, Tilley AJ, Ye S, Seferos DS.

Chem Commun (Camb). 2015 Mar 28;51(25):5475-8. doi: 10.1039/c4cc09312g.


Cilia dysfunction in lung disease.

Tilley AE, Walters MS, Shaykhiev R, Crystal RG.

Annu Rev Physiol. 2015;77:379-406. doi: 10.1146/annurev-physiol-021014-071931. Epub 2014 Oct 29. Review.


Understanding the photothermal heating effect in non-lamellar liquid crystalline systems, and the design of new mixed lipid systems for photothermal on-demand drug delivery.

Fong WK, Hanley TL, Thierry B, Tilley A, Kirby N, Waddington LJ, Boyd BJ.

Phys Chem Chem Phys. 2014 Dec 7;16(45):24936-53. doi: 10.1039/c4cp03635b.


Airway Basal stem/progenitor cells have diminished capacity to regenerate airway epithelium in chronic obstructive pulmonary disease.

Staudt MR, Buro-Auriemma LJ, Walters MS, Salit J, Vincent T, Shaykhiev R, Mezey JG, Tilley AE, Kaner RJ, Ho MW, Crystal RG.

Am J Respir Crit Care Med. 2014 Oct 15;190(8):955-8. doi: 10.1164/rccm.201406-1167LE. No abstract available.

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