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Items: 1 to 20 of 25

1.

Recent insights into the naïve state of human pluripotency and its applications.

Dong C, Fischer LA, Theunissen TW.

Exp Cell Res. 2019 Dec 1;385(1):111645. doi: 10.1016/j.yexcr.2019.111645. Epub 2019 Oct 1.

PMID:
31585117
2.

ZMYM2 inhibits NANOG-mediated reprogramming.

Lawrence M, Theunissen TW, Lombard P, Adams DJ, Silva JCR.

Wellcome Open Res. 2019 Jun 6;4:88. doi: 10.12688/wellcomeopenres.15250.1. eCollection 2019.

3.

Hominoid-Specific Transposable Elements and KZFPs Facilitate Human Embryonic Genome Activation and Control Transcription in Naive Human ESCs.

Pontis J, Planet E, Offner S, Turelli P, Duc J, Coudray A, Theunissen TW, Jaenisch R, Trono D.

Cell Stem Cell. 2019 May 2;24(5):724-735.e5. doi: 10.1016/j.stem.2019.03.012. Epub 2019 Apr 18.

4.

Mechanisms of gene regulation in human embryos and pluripotent stem cells.

Theunissen TW, Jaenisch R.

Development. 2017 Dec 15;144(24):4496-4509. doi: 10.1242/dev.157404. Review.

5.

Human Naive Pluripotent Stem Cells Model X Chromosome Dampening and X Inactivation.

Sahakyan A, Kim R, Chronis C, Sabri S, Bonora G, Theunissen TW, Kuoy E, Langerman J, Clark AT, Jaenisch R, Plath K.

Cell Stem Cell. 2017 Jan 5;20(1):87-101. doi: 10.1016/j.stem.2016.10.006. Epub 2016 Dec 15.

6.

Molecular Criteria for Defining the Naive Human Pluripotent State.

Theunissen TW, Friedli M, He Y, Planet E, O'Neil RC, Markoulaki S, Pontis J, Wang H, Iouranova A, Imbeault M, Duc J, Cohen MA, Wert KJ, Castanon R, Zhang Z, Huang Y, Nery JR, Drotar J, Lungjangwa T, Trono D, Ecker JR, Jaenisch R.

Cell Stem Cell. 2016 Oct 6;19(4):502-515. doi: 10.1016/j.stem.2016.06.011. Epub 2016 Jul 14.

7.

Corrigendum: Failure to replicate the STAP cell phenomenon.

De Los Angeles A, Ferrari F, Fujiwara Y, Mathieu R, Lee S, Lee S, Tu HC, Ross S, Chou S, Nguyen M, Wu Z, Theunissen TW, Powell BE, Imsoonthornruksa S, Chen J, Borkent M, Krupalnik V, Lujan E, Wernig M, Hanna JH, Hochedlinger K, Pei D, Jaenisch R, Deng H, Orkin SH, Park PJ, Daley GQ.

Nature. 2016 Mar 17;531(7594):400. doi: 10.1038/nature16479. Epub 2015 Dec 16. No abstract available.

PMID:
26675720
8.

Failure to replicate the STAP cell phenomenon.

De Los Angeles A, Ferrari F, Fujiwara Y, Mathieu R, Lee S, Lee S, Tu HC, Ross S, Chou S, Nguyen M, Wu Z, Theunissen TW, Powell BE, Imsoonthornruksa S, Chen J, Borkent M, Krupalnik V, Lujan E, Wernig M, Hanna JH, Hochedlinger K, Pei D, Jaenisch R, Deng H, Orkin SH, Park PJ, Daley GQ.

Nature. 2015 Sep 24;525(7570):E6-9. doi: 10.1038/nature15513. No abstract available. Erratum in: Nature. 2016 Mar 17;531(7594):400.

PMID:
26399835
9.

Systematic Identification of Culture Conditions for Induction and Maintenance of Naive Human Pluripotency.

Theunissen TW, Powell BE, Wang H, Mitalipova M, Faddah DA, Reddy J, Fan ZP, Maetzel D, Ganz K, Shi L, Lungjangwa T, Imsoonthornruksa S, Stelzer Y, Rangarajan S, D'Alessio A, Zhang J, Gao Q, Dawlaty MM, Young RA, Gray NS, Jaenisch R.

Cell Stem Cell. 2014 Oct 2;15(4):524-526. doi: 10.1016/j.stem.2014.09.003. Epub 2014 Oct 2. No abstract available.

10.

Systematic Identification of Culture Conditions for Induction and Maintenance of Naive Human Pluripotency.

Theunissen TW, Powell BE, Wang H, Mitalipova M, Faddah DA, Reddy J, Fan ZP, Maetzel D, Ganz K, Shi L, Lungjangwa T, Imsoonthornruksa S, Stelzer Y, Rangarajan S, D'Alessio A, Zhang J, Gao Q, Dawlaty MM, Young RA, Gray NS, Jaenisch R.

Cell Stem Cell. 2014 Oct 2;15(4):523. doi: 10.1016/j.stem.2014.08.002. Epub 2014 Aug 22. No abstract available.

11.

Systematic identification of culture conditions for induction and maintenance of naive human pluripotency.

Theunissen TW, Powell BE, Wang H, Mitalipova M, Faddah DA, Reddy J, Fan ZP, Maetzel D, Ganz K, Shi L, Lungjangwa T, Imsoonthornruksa S, Stelzer Y, Rangarajan S, D'Alessio A, Zhang J, Gao Q, Dawlaty MM, Young RA, Gray NS, Jaenisch R.

Cell Stem Cell. 2014 Oct 2;15(4):471-487. doi: 10.1016/j.stem.2014.07.002. Epub 2014 Jul 24. Erratum in: Cell Stem Cell. 2014 Oct 2;15(4):523.

12.

Molecular control of induced pluripotency.

Theunissen TW, Jaenisch R.

Cell Stem Cell. 2014 Jun 5;14(6):720-34. doi: 10.1016/j.stem.2014.05.002. Review.

13.

Multiplexed activation of endogenous genes by CRISPR-on, an RNA-guided transcriptional activator system.

Cheng AW, Wang H, Yang H, Shi L, Katz Y, Theunissen TW, Rangarajan S, Shivalila CS, Dadon DB, Jaenisch R.

Cell Res. 2013 Oct;23(10):1163-71. doi: 10.1038/cr.2013.122. Epub 2013 Aug 27.

14.

A defined Oct4 level governs cell state transitions of pluripotency entry and differentiation into all embryonic lineages.

Radzisheuskaya A, Chia Gle B, dos Santos RL, Theunissen TW, Castro LF, Nichols J, Silva JC.

Nat Cell Biol. 2013 Jun;15(6):579-90. doi: 10.1038/ncb2742. Epub 2013 Apr 30.

15.

Matrix remodeling maintains embryonic stem cell self-renewal by activating Stat3.

Przybyla LM, Theunissen TW, Jaenisch R, Voldman J.

Stem Cells. 2013 Jun;31(6):1097-106. doi: 10.1002/stem.1360.

16.

NANOG-dependent function of TET1 and TET2 in establishment of pluripotency.

Costa Y, Ding J, Theunissen TW, Faiola F, Hore TA, Shliaha PV, Fidalgo M, Saunders A, Lawrence M, Dietmann S, Das S, Levasseur DN, Li Z, Xu M, Reik W, Silva JC, Wang J.

Nature. 2013 Mar 21;495(7441):370-4. doi: 10.1038/nature11925. Epub 2013 Feb 10.

17.

Reprogramming capacity of Nanog is functionally conserved in vertebrates and resides in a unique homeodomain.

Theunissen TW, Costa Y, Radzisheuskaya A, van Oosten AL, Lavial F, Pain B, Castro LF, Silva JC.

Development. 2011 Nov;138(22):4853-65. doi: 10.1242/dev.068775.

18.

Switching on pluripotency: a perspective on the biological requirement of Nanog.

Theunissen TW, Silva JC.

Philos Trans R Soc Lond B Biol Sci. 2011 Aug 12;366(1575):2222-9. doi: 10.1098/rstb.2011.0003. Review.

19.

Nanog overcomes reprogramming barriers and induces pluripotency in minimal conditions.

Theunissen TW, van Oosten AL, Castelo-Branco G, Hall J, Smith A, Silva JC.

Curr Biol. 2011 Jan 11;21(1):65-71. doi: 10.1016/j.cub.2010.11.074. Epub 2010 Dec 30.

20.

Prmt5 is essential for early mouse development and acts in the cytoplasm to maintain ES cell pluripotency.

Tee WW, Pardo M, Theunissen TW, Yu L, Choudhary JS, Hajkova P, Surani MA.

Genes Dev. 2010 Dec 15;24(24):2772-7. doi: 10.1101/gad.606110.

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