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Items: 1 to 20 of 23

1.

Synthesis and preliminary in vitro kinase inhibition evaluation of new diversely substituted pyrido[3,4-g]quinazoline derivatives.

Zeinyeh W, Esvan YJ, Nauton L, Loaëc N, Meijer L, Théry V, Anizon F, Giraud F, Moreau P.

Bioorg Med Chem Lett. 2016 Sep 1;26(17):4327-9. doi: 10.1016/j.bmcl.2016.07.032. Epub 2016 Jul 16.

PMID:
27469128
2.

Synthesis and biological activity of pyrazole analogues of the staurosporine aglycon K252c.

Esvan YJ, Giraud F, Pereira E, Suchaud V, Nauton L, Théry V, Dezhenkova LG, Kaluzhny DN, Mazov VN, Shtil AA, Anizon F, Moreau P.

Bioorg Med Chem. 2016 Jul 15;24(14):3116-24. doi: 10.1016/j.bmc.2016.05.032. Epub 2016 May 18.

PMID:
27255178
3.

Discovery of pyrido[3,4-g]quinazoline derivatives as CMGC family protein kinase inhibitors: Design, synthesis, inhibitory potency and X-ray co-crystal structure.

Esvan YJ, Zeinyeh W, Boibessot T, Nauton L, Théry V, Knapp S, Chaikuad A, Loaëc N, Meijer L, Anizon F, Giraud F, Moreau P.

Eur J Med Chem. 2016 Aug 8;118:170-7. doi: 10.1016/j.ejmech.2016.04.004. Epub 2016 Apr 5.

PMID:
27128181
4.

Insights into the Thiamine Diphosphate Enzyme Activation Mechanism: Computational Model for Transketolase Using a Quantum Mechanical/Molecular Mechanical Method.

Nauton L, Hélaine V, Théry V, Hecquet L.

Biochemistry. 2016 Apr 12;55(14):2144-52. doi: 10.1021/acs.biochem.5b00787. Epub 2016 Mar 31.

PMID:
26998737
5.

New N-1,N-10-bridged pyrrolo[2,3-a]carbazole-3-carbaldehydes: synthesis and biological activities.

Giraud F, Bourhis M, Nauton L, Théry V, Herfindal L, Døskeland SO, Anizon F, Moreau P.

Bioorg Chem. 2014 Dec;57:108-15. doi: 10.1016/j.bioorg.2014.09.004. Epub 2014 Sep 26.

PMID:
25305721
6.

New potent and selective inhibitor of Pim-1/3 protein kinases sensitizes human colon carcinoma cells to doxorubicin.

Moreau P, Dezhenkova LG, Anizon F, Nauton L, Thery V, Liang S, Kaluzhny DN, Shtil AA.

Anticancer Agents Med Chem. 2014;14(9):1228-36.

PMID:
25175798
7.

Synthesis of pyrazolo[4,3-a]phenanthridines, a new scaffold for Pim kinase inhibition.

Suchaud V, Gavara L, Giraud F, Nauton L, Théry V, Anizon F, Moreau P.

Bioorg Med Chem. 2014 Sep 1;22(17):4704-10. doi: 10.1016/j.bmc.2014.07.011. Epub 2014 Jul 16.

PMID:
25087047
8.

Micelle dynamic simulation and physicochemical characterization of biorelevant media to reflect gastrointestinal environment in fasted and fed states.

Xie X, Cardot JM, Garrait G, Thery V, El-Hajji M, Beyssac E.

Eur J Pharm Biopharm. 2014 Oct;88(2):565-73. doi: 10.1016/j.ejpb.2014.05.020. Epub 2014 Jun 19.

PMID:
24954150
9.

Structure-based design of PDZ ligands as inhibitors of 5-HT(2A) receptor/PSD-95 PDZ1 domain interaction possessing anti-hyperalgesic activity.

Vogrig A, Dorr L, Bouzidi N, Boucherle B, Wattiez AS, Cassier E, Vallon G, Ripoche I, Abrunhosa-Thomas I, Marin P, Nauton L, Thery V, Courteix C, Lian LY, Ducki S.

ACS Chem Biol. 2013 Oct 18;8(10):2209-16. doi: 10.1021/cb400308u. Epub 2013 Aug 23.

PMID:
23895101
10.

Identification of 1,6-dihydropyrazolo[4,3-c]carbazoles and 3,6-dihydropyrazolo[3,4-c]carbazoles as new Pim kinase inhibitors.

Suchaud V, Gavara L, Saugues E, Nauton L, Théry V, Anizon F, Moreau P.

Bioorg Med Chem. 2013 Jul 15;21(14):4102-11. doi: 10.1016/j.bmc.2013.05.011. Epub 2013 May 16.

PMID:
23735828
11.

Identification of pyrrolo[2,3-g]indazoles as new Pim kinase inhibitors.

Gavara L, Suchaud V, Nauton L, Théry V, Anizon F, Moreau P.

Bioorg Med Chem Lett. 2013 Apr 15;23(8):2298-301. doi: 10.1016/j.bmcl.2013.02.074. Epub 2013 Feb 26.

PMID:
23499503
12.

Synthesis and biological activities of 4-substituted pyrrolo[2,3-a]carbazole Pim kinase inhibitors.

Giraud F, Akué-Gédu R, Nauton L, Candelon N, Debiton E, Théry V, Anizon F, Moreau P.

Eur J Med Chem. 2012 Oct;56:225-36. doi: 10.1016/j.ejmech.2012.08.029. Epub 2012 Aug 30.

PMID:
22982527
13.

Access to functionalised silver(I) and gold(I) N-heterocyclic carbenes by [2 + 3] dipolar cycloadditions.

Hospital A, Gibard C, Gaulier C, Nauton L, Théry V, El-Ghozzi M, Avignant D, Cisnetti F, Gautier A.

Dalton Trans. 2012 Jun 14;41(22):6803-12. doi: 10.1039/c2dt30249g. Epub 2012 Apr 20.

PMID:
22517562
14.

Gender and line size factors modulate the deviations of the subjective visual vertical induced by head tilt.

Luyat M, Noël M, Thery V, Gentaz E.

BMC Neurosci. 2012 Mar 15;13:28. doi: 10.1186/1471-2202-13-28.

15.

Synthesis and molecular modeling study of new trimeric quinoline derivatives.

Saugues E, Nauton L, Théry V, Anizon F, Moreau P.

Bioorg Chem. 2011 Aug;39(4):143-50. doi: 10.1016/j.bioorg.2011.07.001. Epub 2011 Jul 14.

PMID:
21807395
16.

Synthesis, protein kinase inhibitory potencies, and in vitro antiproliferative activities of meridianin derivatives.

Giraud F, Alves G, Debiton E, Nauton L, Théry V, Durieu E, Ferandin Y, Lozach O, Meijer L, Anizon F, Pereira E, Moreau P.

J Med Chem. 2011 Jul 14;54(13):4474-89. doi: 10.1021/jm200464w. Epub 2011 Jun 10.

PMID:
21623630
17.

Synthesis, Pim kinase inhibitory potencies and in vitro antiproliferative activities of diversely substituted pyrrolo[2,3-a]carbazoles.

Akué-Gédu R, Nauton L, Théry V, Bain J, Cohen P, Anizon F, Moreau P.

Bioorg Med Chem. 2010 Sep 15;18(18):6865-73. doi: 10.1016/j.bmc.2010.07.036. Epub 2010 Aug 19.

PMID:
20728368
18.

12-Helix folding of cyclobutane beta-amino acid oligomers.

Fernandes C, Faure S, Pereira E, Théry V, Declerck V, Guillot R, Aitken DJ.

Org Lett. 2010 Aug 20;12(16):3606-9. doi: 10.1021/ol101267u.

PMID:
20704401
19.

Synthesis and solution conformation of homo-beta-peptides consisting of N-mannofuranosyl-3-ulosonic acids.

Andreini M, Taillefumier C, Chrétien F, Thery V, Chapleur Y.

J Org Chem. 2009 Oct 16;74(20):7651-9. doi: 10.1021/jo900966b.

PMID:
19775149
20.

Cyclic beta-peptoids.

Roy O, Faure S, Thery V, Didierjean C, Taillefumier C.

Org Lett. 2008 Mar 6;10(5):921-4. doi: 10.1021/ol7030763. Epub 2008 Feb 6.

PMID:
18251550

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