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Items: 1 to 20 of 32

1.

Functional Analysis of ESCRT-Positive Extracellular Vesicles in the Drosophila Wing Imaginal Disc.

Matusek T, Thérond P, Fürthauer M.

Methods Mol Biol. 2019;1998:31-47. doi: 10.1007/978-1-4939-9492-2_3.

PMID:
31250292
2.

Protein association changes in the Hedgehog signaling complex mediate differential signaling strength.

Giordano C, Ruel L, Poux C, Therond P.

Development. 2018 Dec 12;145(24). pii: dev166850. doi: 10.1242/dev.166850.

3.

Endocytosis of Hedgehog through dispatched regulates long-range signaling.

D'Angelo G, Matusek T, Pizette S, Thérond PP.

Dev Cell. 2015 Feb 9;32(3):290-303. doi: 10.1016/j.devcel.2014.12.004. Epub 2015 Jan 22.

4.

The ESCRT machinery regulates the secretion and long-range activity of Hedgehog.

Matusek T, Wendler F, Polès S, Pizette S, D'Angelo G, Fürthauer M, Thérond PP.

Nature. 2014 Dec 4;516(7529):99-103. doi: 10.1038/nature13847.

PMID:
25471885
5.

Switch of PKA substrates from Cubitus interruptus to Smoothened in the Hedgehog signalosome complex.

Ranieri N, Thérond PP, Ruel L.

Nat Commun. 2014 Oct 7;5:5034. doi: 10.1038/ncomms6034.

PMID:
25289679
6.

The mechanisms of Hedgehog signalling and its roles in development and disease.

Briscoe J, Thérond PP.

Nat Rev Mol Cell Biol. 2013 Jul;14(7):416-29. doi: 10.1038/nrm3598. Epub 2013 May 30. Review.

PMID:
23719536
7.

Dally and Notum regulate the switch between low and high level Hedgehog pathway signalling.

Ayers KL, Mteirek R, Cervantes A, Lavenant-Staccini L, Thérond PP, Gallet A.

Development. 2012 Sep;139(17):3168-79. doi: 10.1242/dev.078402.

8.

A genome-wide RNAi screen identifies regulators of cholesterol-modified hedgehog secretion in Drosophila.

Aikin R, Cervantes A, D'Angelo G, Ruel L, Lacas-Gervais S, Schaub S, Thérond P.

PLoS One. 2012;7(3):e33665. doi: 10.1371/journal.pone.0033665. Epub 2012 Mar 14.

9.

Release and transportation of Hedgehog molecules.

Thérond PP.

Curr Opin Cell Biol. 2012 Apr;24(2):173-80. doi: 10.1016/j.ceb.2012.02.001. Epub 2012 Feb 24. Review.

PMID:
22366329
10.

Distinct phosphorylations on kinesin costal-2 mediate differential hedgehog signaling strength.

Ranieri N, Ruel L, Gallet A, Raisin S, Thérond PP.

Dev Cell. 2012 Feb 14;22(2):279-94. doi: 10.1016/j.devcel.2011.12.002. Epub 2012 Feb 2.

11.

The long-range activity of Hedgehog is regulated in the apical extracellular space by the glypican Dally and the hydrolase Notum.

Ayers KL, Gallet A, Staccini-Lavenant L, Thérond PP.

Dev Cell. 2010 Apr 20;18(4):605-20. doi: 10.1016/j.devcel.2010.02.015.

12.

Evaluating Smoothened as a G-protein-coupled receptor for Hedgehog signalling.

Ayers KL, Thérond PP.

Trends Cell Biol. 2010 May;20(5):287-98. doi: 10.1016/j.tcb.2010.02.002. Epub 2010 Mar 5. Review.

PMID:
20207148
13.

The full-length unprocessed hedgehog protein is an active signaling molecule.

Tokhunts R, Singh S, Chu T, D'Angelo G, Baubet V, Goetz JA, Huang Z, Yuan Z, Ascano M, Zavros Y, Thérond PP, Kunes S, Dahmane N, Robbins DJ.

J Biol Chem. 2010 Jan 22;285(4):2562-8. doi: 10.1074/jbc.M109.078626. Epub 2009 Nov 17.

14.

Variations in Hedgehog signaling: divergence and perpetuation in Sufu regulation of Gli.

Ruel L, Thérond PP.

Genes Dev. 2009 Aug 15;23(16):1843-8. doi: 10.1101/gad.1838109.

15.

Tow (Target of Wingless), a novel repressor of the Hedgehog pathway in Drosophila.

Ayers KL, Rodriguez R, Gallet A, Ruel L, Thérond P.

Dev Biol. 2009 May 15;329(2):280-93. doi: 10.1016/j.ydbio.2009.02.037. Epub 2009 Mar 10.

16.

Glycosphingolipids control the extracellular gradient of the Drosophila EGFR ligand Gurken.

Pizette S, Rabouille C, Cohen SM, Thérond P.

Development. 2009 Feb;136(4):551-61. doi: 10.1242/dev.031104. Epub 2009 Jan 14.

17.

Control of antagonistic components of the hedgehog signaling pathway by microRNAs in Drosophila.

Friggi-Grelin F, Lavenant-Staccini L, Therond P.

Genetics. 2008 May;179(1):429-39. doi: 10.1534/genetics.107.083733.

18.

Cellular trafficking of the glypican Dally-like is required for full-strength Hedgehog signaling and wingless transcytosis.

Gallet A, Staccini-Lavenant L, Thérond PP.

Dev Cell. 2008 May;14(5):712-25. doi: 10.1016/j.devcel.2008.03.001.

19.

The role of kinases in the Hedgehog signalling pathway.

Aikin RA, Ayers KL, Thérond PP.

EMBO Rep. 2008 Apr;9(4):330-6. doi: 10.1038/embor.2008.38. Review.

20.

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