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Items: 1 to 20 of 114


Autoimmunity to Vimentin Is Associated with Outcomes of Patients with Idiopathic Pulmonary Fibrosis.

Li FJ, Surolia R, Li H, Wang Z, Kulkarni T, Liu G, de Andrade JA, Kass DJ, Thannickal VJ, Duncan SR, Antony VB.

J Immunol. 2017 Sep 1;199(5):1596-1605. doi: 10.4049/jimmunol.1700473. Epub 2017 Jul 28.


Serpine 1 induces alveolar type II cell senescence through activating p53-p21-Rb pathway in fibrotic lung disease.

Jiang C, Liu G, Luckhardt T, Antony V, Zhou Y, Carter AB, Thannickal VJ, Liu RM.

Aging Cell. 2017 Oct;16(5):1114-1124. doi: 10.1111/acel.12643. Epub 2017 Jul 19.


3D pulmospheres serve as a personalized and predictive multicellular model for assessment of antifibrotic drugs.

Surolia R, Li FJ, Wang Z, Li H, Liu G, Zhou Y, Luckhardt T, Bae S, Liu RM, Rangarajan S, de Andrade J, Thannickal VJ, Antony VB.

JCI Insight. 2017 Apr 20;2(8). pii: 94088. doi: 10.1172/jci.insight.94088. [Epub ahead of print] No abstract available.


3D pulmospheres serve as a personalized and predictive multicellular model for assessment of antifibrotic drugs.

Surolia R, Li FJ, Wang Z, Li H, Liu G, Zhou Y, Luckhardt T, Bae S, Liu RM, Rangarajan S, de Andrade J, Thannickal VJ, Antony VB.

JCI Insight. 2017 Jan 26;2(2):e91377. doi: 10.1172/jci.insight.91377.


Tristetraprolin Down-Regulation Contributes to Persistent TNF-Alpha Expression Induced by Cigarette Smoke Extract through a Post-Transcriptional Mechanism.

Zhao XK, Che P, Cheng ML, Zhang Q, Mu M, Li H, Luo Y, Liang YD, Luo XH, Gao CQ, Jackson PL, Wells JM, Zhou Y, Hu M, Cai G, Thannickal VJ, Steele C, Blalock JE, Han X, Chen CY, Ding Q.

PLoS One. 2016 Dec 2;11(12):e0167451. doi: 10.1371/journal.pone.0167451. eCollection 2016.


Developmental Reprogramming in Mesenchymal Stromal Cells of Human Subjects with Idiopathic Pulmonary Fibrosis.

Chanda D, Kurundkar A, Rangarajan S, Locy M, Bernard K, Sharma NS, Logsdon NJ, Liu H, Crossman DK, Horowitz JC, De Langhe S, Thannickal VJ.

Sci Rep. 2016 Nov 21;6:37445. doi: 10.1038/srep37445.


Exosomes in immunoregulation of chronic lung diseases.

Hough KP, Chanda D, Duncan SR, Thannickal VJ, Deshane JS.

Allergy. 2017 Apr;72(4):534-544. doi: 10.1111/all.13086. Epub 2016 Dec 8. Review.


Attenuated heme oxygenase-1 responses predispose the elderly to pulmonary nontuberculous mycobacterial infections.

Surolia R, Karki S, Wang Z, Kulkarni T, Li FJ, Vohra S, Batra H, Nick JA, Duncan SR, Thannickal VJ, Steyn AJ, Agarwal A, Antony VB.

Am J Physiol Lung Cell Mol Physiol. 2016 Nov 1;311(5):L928-L940. doi: 10.1152/ajplung.00397.2015. Epub 2016 Sep 30.


Redox mechanisms in age-related lung fibrosis.

Kurundkar A, Thannickal VJ.

Redox Biol. 2016 Oct;9:67-76. doi: 10.1016/j.redox.2016.06.005. Epub 2016 Jun 25. Review.


Indoleamine 2,3-dioxygenase regulates anti-tumor immunity in lung cancer by metabolic reprogramming of immune cells in the tumor microenvironment.

Schafer CC, Wang Y, Hough KP, Sawant A, Grant SC, Thannickal VJ, Zmijewski J, Ponnazhagan S, Deshane JS.

Oncotarget. 2016 Nov 15;7(46):75407-75424. doi: 10.18632/oncotarget.12249.


Epigenetic Regulation of Caveolin-1 Gene Expression in Lung Fibroblasts.

Sanders YY, Liu H, Scruggs AM, Duncan SR, Huang SK, Thannickal VJ.

Am J Respir Cell Mol Biol. 2017 Jan;56(1):50-61. doi: 10.1165/rcmb.2016-0034OC.


Mechanosensing by the α6-integrin confers an invasive fibroblast phenotype and mediates lung fibrosis.

Chen H, Qu J, Huang X, Kurundkar A, Zhu L, Yang N, Venado A, Ding Q, Liu G, Antony VB, Thannickal VJ, Zhou Y.

Nat Commun. 2016 Aug 18;7:12564. doi: 10.1038/ncomms12564.


Nuclear Factor-Erythroid-2-Related Factor 2 in Aging and Lung Fibrosis.

Swamy SM, Rajasekaran NS, Thannickal VJ.

Am J Pathol. 2016 Jul;186(7):1712-23. doi: 10.1016/j.ajpath.2016.02.022. Review.


Alveolar epithelial disintegrity in pulmonary fibrosis.

Kulkarni T, de Andrade J, Zhou Y, Luckhardt T, Thannickal VJ.

Am J Physiol Lung Cell Mol Physiol. 2016 Aug 1;311(2):L185-91. doi: 10.1152/ajplung.00115.2016. Epub 2016 May 27. Review.


A bundled care approach to patients with idiopathic pulmonary fibrosis improves transplant-free survival.

Kulkarni T, Willoughby J, Acosta Lara Mdel P, Kim YI, Ramachandran R, Alexander CB, Luckhardt T, Thannickal VJ, de Andrade JA.

Respir Med. 2016 Jun;115:33-8. doi: 10.1016/j.rmed.2016.04.010. Epub 2016 Apr 20.


Getting to the core of fibrosis: targeting redox imbalance in aging.

Hecker L, Thannickal VJ.

Ann Transl Med. 2016 Mar;4(5):93. doi: 10.21037/atm.2015.12.45. No abstract available.


Macrophage Akt1 Kinase-Mediated Mitophagy Modulates Apoptosis Resistance and Pulmonary Fibrosis.

Larson-Casey JL, Deshane JS, Ryan AJ, Thannickal VJ, Carter AB.

Immunity. 2016 Mar 15;44(3):582-596. doi: 10.1016/j.immuni.2016.01.001. Epub 2016 Feb 23.


The matricellular protein CCN1 enhances TGF-β1/SMAD3-dependent profibrotic signaling in fibroblasts and contributes to fibrogenic responses to lung injury.

Kurundkar AR, Kurundkar D, Rangarajan S, Locy ML, Zhou Y, Liu RM, Zmijewski J, Thannickal VJ.

FASEB J. 2016 Jun;30(6):2135-50. doi: 10.1096/fj.201500173. Epub 2016 Feb 16.


Matrix Remodeling in Pulmonary Fibrosis and Emphysema.

Kulkarni T, O'Reilly P, Antony VB, Gaggar A, Thannickal VJ.

Am J Respir Cell Mol Biol. 2016 Jun;54(6):751-60. doi: 10.1165/rcmb.2015-0166PS. Review.


Targeted Therapy for Idiopathic Pulmonary Fibrosis: Where To Now?

Rangarajan S, Locy ML, Luckhardt TR, Thannickal VJ.

Drugs. 2016 Mar;76(3):291-300. doi: 10.1007/s40265-015-0523-6. Review.

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