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Correlation of an epigenetic mitotic clock with cancer risk.

Yang Z, Wong A, Kuh D, Paul DS, Rakyan VK, Leslie RD, Zheng SC, Widschwendter M, Beck S, Teschendorff AE.

Genome Biol. 2016 Oct 3;17(1):205.


The lncRNA HOTAIR impacts on mesenchymal stem cells via triple helix formation.

Kalwa M, Hänzelmann S, Otto S, Kuo CC, Franzen J, Joussen S, Fernandez-Rebollo E, Rath B, Koch C, Hofmann A, Lee SH, Teschendorff AE, Denecke B, Lin Q, Widschwendter M, Weinhold E, Costa IG, Wagner W.

Nucleic Acids Res. 2016 Sep 14. pii: gkw802.


The multi-omic landscape of transcription factor inactivation in cancer.

Teschendorff AE, Zheng SC, Feber A, Yang Z, Beck S, Widschwendter M.

Genome Med. 2016 Aug 25;8(1):89. doi: 10.1186/s13073-016-0342-8.


Menopause accelerates biological aging.

Levine ME, Lu AT, Chen BH, Hernandez DG, Singleton AB, Ferrucci L, Bandinelli S, Salfati E, Manson JE, Quach A, Kusters CD, Kuh D, Wong A, Teschendorff AE, Widschwendter M, Ritz BR, Absher D, Assimes TL, Horvath S.

Proc Natl Acad Sci U S A. 2016 Aug 16;113(33):9327-32. doi: 10.1073/pnas.1604558113.


DNA Methylation Signatures in Vaginal Fluid Samples for Detection of Cervical and Endometrial Cancer.

Doufekas K, Zheng SC, Ghazali S, Wong M, Mohamed Y, Jones A, Reisel D, Mould T, Olaitan A, Macdonald N, Teschendorff AE, Widschwendter M.

Int J Gynecol Cancer. 2016 Jun 2.


Erratum to: The integrative epigenomic-transcriptomic landscape of ER positive breast cancer.

Gao Y, Jones A, Fasching PA, Ruebner M, Beckmann MW, Widschwendter M, Teschendorff AE.

Clin Epigenetics. 2016 Jun 1;8:63. doi: 10.1186/s13148-016-0231-4. No abstract available.


Epigenetic drift, epigenetic clocks and cancer risk.

Zheng SC, Widschwendter M, Teschendorff AE.

Epigenomics. 2016 May;8(5):705-19. doi: 10.2217/epi-2015-0017.


Stochastic epigenetic outliers can define field defects in cancer.

Teschendorff AE, Jones A, Widschwendter M.

BMC Bioinformatics. 2016 Apr 22;17:178. doi: 10.1186/s12859-016-1056-z.


Tissue-independent and tissue-specific patterns of DNA methylation alteration in cancer.

Chen Y, Breeze CE, Zhen S, Beck S, Teschendorff AE.

Epigenetics Chromatin. 2016 Mar 8;9:10. doi: 10.1186/s13072-016-0058-4.


DNA methylation outliers in normal breast tissue identify field defects that are enriched in cancer.

Teschendorff AE, Gao Y, Jones A, Ruebner M, Beckmann MW, Wachter DL, Fasching PA, Widschwendter M.

Nat Commun. 2016 Jan 29;7:10478. doi: 10.1038/ncomms10478.


The integrative epigenomic-transcriptomic landscape of ER positive breast cancer.

Gao Y, Jones A, Fasching PA, Ruebner M, Beckmann MW, Widschwendter M, Teschendorff AE.

Clin Epigenetics. 2015 Dec 9;7:126. doi: 10.1186/s13148-015-0159-0. Erratum in: Clin Epigenetics. 2016;8:63.


Glioblastoma Stem Cells Respond to Differentiation Cues but Fail to Undergo Commitment and Terminal Cell-Cycle Arrest.

Carén H, Stricker SH, Bulstrode H, Gagrica S, Johnstone E, Bartlett TE, Feber A, Wilson G, Teschendorff AE, Bertone P, Beck S, Pollard SM.

Stem Cell Reports. 2015 Nov 10;5(5):829-42.


HOTAIR and its surrogate DNA methylation signature indicate carboplatin resistance in ovarian cancer.

Teschendorff AE, Lee SH, Jones A, Fiegl H, Kalwa M, Wagner W, Chindera K, Evans I, Dubeau L, Orjalo A, Horlings HM, Niederreiter L, Kaser A, Yang W, Goode EL, Fridley BL, Jenner RG, Berns EM, Wik E, Salvesen HB, Wisman GB, van der Zee AG, Davidson B, Trope CG, Lambrechts S, Vergote I, Calvert H, Jacobs IJ, Widschwendter M.

Genome Med. 2015 Oct 24;7:108. doi: 10.1186/s13073-015-0233-4.


Variational Bayesian Matrix Factorization for Bounded Support Data.

Ma Z, Teschendorff AE, Leijon A, Qiao Y, Zhang H, Guo J.

IEEE Trans Pattern Anal Mach Intell. 2015 Apr;37(4):876-89. doi: 10.1109/TPAMI.2014.2353639.


Expression profiling of nuclear receptors in breast cancer identifies TLX as a mediator of growth and invasion in triple-negative breast cancer.

Lin ML, Patel H, Remenyi J, Banerji CR, Lai CF, Periyasamy M, Lombardo Y, Busonero C, Ottaviani S, Passey A, Quinlan PR, Purdie CA, Jordan LB, Thompson AM, Finn RS, Rueda OM, Caldas C, Gil J, Coombes RC, Fuller-Pace FV, Teschendorff AE, Buluwela L, Ali S.

Oncotarget. 2015 Aug 28;6(25):21685-703.


Correlation of Smoking-Associated DNA Methylation Changes in Buccal Cells With DNA Methylation Changes in Epithelial Cancer.

Teschendorff AE, Yang Z, Wong A, Pipinikas CP, Jiao Y, Jones A, Anjum S, Hardy R, Salvesen HB, Thirlwell C, Janes SM, Kuh D, Widschwendter M.

JAMA Oncol. 2015 Jul;1(4):476-85. doi: 10.1001/jamaoncol.2015.1053. Erratum in: JAMA Oncol. 2015 Jul;1(4):544.


An integrative pan-cancer-wide analysis of epigenetic enzymes reveals universal patterns of epigenomic deregulation in cancer.

Yang Z, Jones A, Widschwendter M, Teschendorff AE.

Genome Biol. 2015 Jul 14;16:140. doi: 10.1186/s13059-015-0699-9.


Increased signaling entropy in cancer requires the scale-free property of protein interaction networks.

Teschendorff AE, Banerji CR, Severini S, Kuehn R, Sollich P.

Sci Rep. 2015 Apr 28;5:9646. doi: 10.1038/srep09646.


Intra-tumour signalling entropy determines clinical outcome in breast and lung cancer.

Banerji CR, Severini S, Caldas C, Teschendorff AE.

PLoS Comput Biol. 2015 Mar 20;11(3):e1004115. doi: 10.1371/journal.pcbi.1004115.

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