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Items: 1 to 20 of 90

1.

Loss of Tet1-Associated 5-Hydroxymethylcytosine Is Concomitant with Aberrant Promoter Hypermethylation in Liver Cancer.

Thomson JP, Ottaviano R, Unterberger EB, Lempiäinen H, Muller A, Terranova R, Illingworth RS, Webb S, Kerr AR, Lyall MJ, Drake AJ, Wolf CR, Moggs JG, Schwarz M, Meehan RR.

Cancer Res. 2016 May 15;76(10):3097-108. doi: 10.1158/0008-5472.CAN-15-1910.

2.

Reciprocal changes in DNA methylation and hydroxymethylation and a broad repressive epigenetic switch characterize FMR1 transcriptional silencing in fragile X syndrome.

Brasa S, Mueller A, Jacquemont S, Hahne F, Rozenberg I, Peters T, He Y, McCormack C, Gasparini F, Chibout SD, Grenet O, Moggs J, Gomez-Mancilla B, Terranova R.

Clin Epigenetics. 2016 Feb 5;8:15. doi: 10.1186/s13148-016-0181-x.

3.

Evaluation of 5-methylcytosine and 5-hydroxymethylcytosine as potential biomarkers for characterisation of chemical allergens.

Chapman VL, Terranova R, Moggs JG, Kimber I, Dearman RJ.

Toxicology. 2016 Jan 18;340:17-26. doi: 10.1016/j.tox.2015.12.003.

PMID:
26732893
4.

A novel RET gene mutation in a patient with apparently sporadic pheochromocytoma.

Scollo C, Russo M, De Gregorio L, Terranova R, Mangione E, Castoro C, Squatrito S, Pellegriti G.

Endocr J. 2016;63(1):87-91. doi: 10.1507/endocrj.EJ15-0399.

5.

Familial Non-Medullary Thyroid Cancer Represents an Independent Risk Factor for Increased Cancer Aggressiveness: A Retrospective Analysis of 74 Families.

Tavarelli M, Russo M, Terranova R, Scollo C, Spadaro A, Sapuppo G, Malandrino P, Masucci R, Squatrito S, Pellegriti G.

Front Endocrinol (Lausanne). 2015 Aug 3;6:117. doi: 10.3389/fendo.2015.00117.

6.

Phenobarbital induces cell cycle transcriptional responses in mouse liver humanized for constitutive androstane and pregnane x receptors.

Luisier R, Lempiäinen H, Scherbichler N, Braeuning A, Geissler M, Dubost V, Müller A, Scheer N, Chibout SD, Hara H, Picard F, Theil D, Couttet P, Vitobello A, Grenet O, Grasl-Kraupp B, Ellinger-Ziegelbauer H, Thomson JP, Meehan RR, Elcombe CR, Henderson CJ, Wolf CR, Schwarz M, Moulin P, Terranova R, Moggs JG.

Toxicol Sci. 2014 Jun;139(2):501-11. doi: 10.1093/toxsci/kfu038.

7.

Chemical allergen induced perturbations of the mouse lymph node DNA methylome.

Chapman VL, Zollinger T, Terranova R, Moggs J, Kimber I, Dearman RJ.

Toxicol Sci. 2014 Jun;139(2):350-61. doi: 10.1093/toxsci/kfu047.

8.

Ha-ras and β-catenin oncoproteins orchestrate metabolic programs in mouse liver tumors.

Unterberger EB, Eichner J, Wrzodek C, Lempiäinen H, Luisier R, Terranova R, Metzger U, Plummer S, Knorpp T, Braeuning A, Moggs J, Templin MF, Honndorf V, Piotto M, Zell A, Schwarz M.

Int J Cancer. 2014 Oct 1;135(7):1574-85. doi: 10.1002/ijc.28798.

9.

Computational modeling identifies key gene regulatory interactions underlying phenobarbital-mediated tumor promotion.

Luisier R, Unterberger EB, Goodman JI, Schwarz M, Moggs J, Terranova R, van Nimwegen E.

Nucleic Acids Res. 2014 Apr;42(7):4180-95. doi: 10.1093/nar/gkt1415.

10.

Comparative analysis of affinity-based 5-hydroxymethylation enrichment techniques.

Thomson JP, Hunter JM, Nestor CE, Dunican DS, Terranova R, Moggs JG, Meehan RR.

Nucleic Acids Res. 2013 Dec;41(22):e206. doi: 10.1093/nar/gkt1080. Erratum in: Nucleic Acids Res. . 2014 Apr;42(6):4142.

11.

Dynamic changes in 5-hydroxymethylation signatures underpin early and late events in drug exposed liver.

Thomson JP, Hunter JM, Lempiäinen H, Müller A, Terranova R, Moggs JG, Meehan RR.

Nucleic Acids Res. 2013 Jun;41(11):5639-54. doi: 10.1093/nar/gkt232.

12.

Increased mortality in patients with differentiated thyroid cancer associated with Graves' disease.

Pellegriti G, Mannarino C, Russo M, Terranova R, Marturano I, Vigneri R, Belfiore A.

J Clin Endocrinol Metab. 2013 Mar;98(3):1014-21. doi: 10.1210/jc.2012-2843.

PMID:
23348395
13.

Identification of Dlk1-Dio3 imprinted gene cluster noncoding RNAs as novel candidate biomarkers for liver tumor promotion.

Lempiäinen H, Couttet P, Bolognani F, Müller A, Dubost V, Luisier R, Del Rio Espinola A, Vitry V, Unterberger EB, Thomson JP, Treindl F, Metzger U, Wrzodek C, Hahne F, Zollinger T, Brasa S, Kalteis M, Marcellin M, Giudicelli F, Braeuning A, Morawiec L, Zamurovic N, Längle U, Scheer N, Schübeler D, Goodman J, Chibout SD, Marlowe J, Theil D, Heard DJ, Grenet O, Zell A, Templin MF, Meehan RR, Wolf RC, Elcombe CR, Schwarz M, Moulin P, Terranova R, Moggs JG.

Toxicol Sci. 2013 Feb;131(2):375-86. doi: 10.1093/toxsci/kfs303.

14.

Non-genotoxic carcinogen exposure induces defined changes in the 5-hydroxymethylome.

Thomson JP, Lempiäinen H, Hackett JA, Nestor CE, Müller A, Bolognani F, Oakeley EJ, Schübeler D, Terranova R, Reinhardt D, Moggs JG, Meehan RR.

Genome Biol. 2012 Oct 3;13(10):R93. doi: 10.1186/gb-2012-13-10-r93.

15.

Regulation of allergic responses to chemicals and drugs: possible roles of epigenetic mechanisms.

Moggs JG, Terranova R, Kammüller ME, Chibout SD, Chapman V, Dearman RJ, Kimber I.

Toxicol Sci. 2012 Nov;130(1):60-9. doi: 10.1093/toxsci/kfs207. Review.

16.

Target genes of Topoisomerase IIβ regulate neuronal survival and are defined by their chromatin state.

Tiwari VK, Burger L, Nikoletopoulou V, Deogracias R, Thakurela S, Wirbelauer C, Kaut J, Terranova R, Hoerner L, Mielke C, Boege F, Murr R, Peters AH, Barde YA, Schübeler D.

Proc Natl Acad Sci U S A. 2012 Apr 17;109(16):E934-43. doi: 10.1073/pnas.1119798109.

17.

Phenobarbital mediates an epigenetic switch at the constitutive androstane receptor (CAR) target gene Cyp2b10 in the liver of B6C3F1 mice.

Lempiäinen H, Müller A, Brasa S, Teo SS, Roloff TC, Morawiec L, Zamurovic N, Vicart A, Funhoff E, Couttet P, Schübeler D, Grenet O, Marlowe J, Moggs J, Terranova R.

PLoS One. 2011 Mar 24;6(3):e18216. doi: 10.1371/journal.pone.0018216.

18.

Polycomb group proteins Ezh2 and Rnf2 direct genomic contraction and imprinted repression in early mouse embryos.

Terranova R, Yokobayashi S, Stadler MB, Otte AP, van Lohuizen M, Orkin SH, Peters AH.

Dev Cell. 2008 Nov;15(5):668-79. doi: 10.1016/j.devcel.2008.08.015.

19.

[The many faces of constitutive heterochromatin].

Terranova R.

Med Sci (Paris). 2008 Aug-Sep;24(8-9):720-4. doi: 10.1051/medsci/20082489720. Review. French.

20.

Heterokaryon-based reprogramming of human B lymphocytes for pluripotency requires Oct4 but not Sox2.

Pereira CF, Terranova R, Ryan NK, Santos J, Morris KJ, Cui W, Merkenschlager M, Fisher AG.

PLoS Genet. 2008 Sep 5;4(9):e1000170. doi: 10.1371/journal.pgen.1000170.

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