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Reversing Dabigatran Anticoagulation with Prothrombin Complex Concentrate versus Idarucizumab as Part of Multimodal Hemostatic Intervention in an Animal Model of Polytrauma.

Honickel M, Braunschweig T, Rossaint R, Stoppe C, Ten Cate H, Grottke O.

Anesthesiology. 2017 Aug 30. doi: 10.1097/ALN.0000000000001856. [Epub ahead of print]


Platelet populations and priming in hematological diseases.

Baaten CCFMJ, Ten Cate H, van der Meijden PEJ, Heemskerk JWM.

Blood Rev. 2017 Jul 22. pii: S0268-960X(17)30046-2. doi: 10.1016/j.blre.2017.07.004. [Epub ahead of print] Review.


Age-related diagnostic value of D-dimer testing and the role of inflammation in patients with suspected deep vein thrombosis.

Prochaska JH, Frank B, Nagler M, Lamparter H, Weißer G, Schulz A, Eggebrecht L, Göbel S, Arnold N, Panova-Noeva M, Hermanns I, Pinto A, Konstantinides S, Ten Cate H, Lackner KJ, Münzel T, Espinola-Klein C, Wild PS.

Sci Rep. 2017 Jul 4;7(1):4591. doi: 10.1038/s41598-017-04843-x.


Empirically Reduced Dosages of Tinzaparin in Patients with Moderate-to-Severe Renal Insufficiency Lead to Inadequate Anti-Xa Levels.

Olie RH, Meertens NEL, Henskens YMC, Ten Cate H.

Nephron. 2017 Jun 30. doi: 10.1159/000477474. [Epub ahead of print]


Coagulation factor and protease pathways in thrombosis and cardiovascular disease.

Ten Cate H, Hackeng TM, García de Frutos P.

Thromb Haemost. 2017 Jun 28;117(7):1265-1271. doi: 10.1160/TH17-02-0079. Epub 2017 Jun 8.


Is a normal computed tomography pulmonary angiography safe to rule out acute pulmonary embolism in patients with a likely clinical probability? A patient-level meta-analysis.

van der Hulle T, van Es N, den Exter PL, van Es J, Mos ICM, Douma RA, Kruip MJHA, Hovens MMC, Ten Wolde M, Nijkeuter M, Ten Cate H, Kamphuisen PW, Büller HR, Huisman MV, Klok FA.

Thromb Haemost. 2017 Jul 26;117(8):1622-1629. doi: 10.1160/TH17-02-0076. Epub 2017 Jun 1.


Thromboelastometry and Thrombelastography Analysis under Normal Physiological Conditions - Systematic Review.

Adler M, Ivic S, Bodmer NS, Ten Cate H, Bachmann LM, Wuillemin WA, Nagler M.

Transfus Med Hemother. 2017 Apr;44(2):78-83. doi: 10.1159/000464297. Epub 2017 Mar 8.


Increased Clot Formation in the Absence of Increased Thrombin Generation in Patients with Peripheral Arterial Disease: A Case-Control Study.

Kleinegris MF, Konings J, Daemen JW, Henskens Y, de Laat B, Spronk HMH, Ten Cate-Hoek AJ, Ten Cate H.

Front Cardiovasc Med. 2017 Apr 20;4:23. doi: 10.3389/fcvm.2017.00023. eCollection 2017.


Decreased prothrombin conversion and reduced thrombin inactivation explain rebalanced thrombin generation in liver cirrhosis.

Kremers RMW, Kleinegris MC, Ninivaggi M, de Laat B, Ten Cate H, Koek GH, Wagenvoord RJ, Hemker HC.

PLoS One. 2017 May 4;12(5):e0177020. doi: 10.1371/journal.pone.0177020. eCollection 2017.


Prediction of bleeding risk in patients taking vitamin K antagonists using thrombin generation testing.

Bloemen S, Zwaveling S, Ten Cate H, Ten Cate-Hoek A, de Laat B.

PLoS One. 2017 May 4;12(5):e0176967. doi: 10.1371/journal.pone.0176967. eCollection 2017.


e-Health-based management of patients receiving oral anticoagulation therapy: results from the observational thrombEVAL study.

Prochaska JH, Göbel S, Keller K, Coldewey M, Ullmann A, Lamparter H, Schulz A, Schinzel H, Bickel C, Lauterbach M, Michal M, Hardt R, Binder H, Espinola-Klein C, Lackner KJ, Ten Cate H, Münzel T, Wild PS.

J Thromb Haemost. 2017 Jul;15(7):1375-1385. doi: 10.1111/jth.13727. Epub 2017 Jun 6.


Dose requirements for idarucizumab reversal of dabigatran in a lethal porcine trauma model with continuous bleeding.

Honickel M, Spronk HM, Rossaint R, Stoppe C, van Ryn J, Ten Cate H, Grottke O.

Thromb Haemost. 2017 Jun 28;117(7):1370-1378. doi: 10.1160/TH16-11-0824. Epub 2017 Apr 20.


Prethrombotic State in Young Very Low-Risk Patients With Atrial Fibrillation.

Hobbelt AH, Spronk HM, Crijns HJGM, Ten Cate H, Rienstra M, Van Gelder IC.

J Am Coll Cardiol. 2017 Apr 18;69(15):1990-1992. doi: 10.1016/j.jacc.2017.01.057. No abstract available.


Rivaroxaban or Aspirin for Extended Treatment of Venous Thromboembolism.

Weitz JI, Lensing AWA, Prins MH, Bauersachs R, Beyer-Westendorf J, Bounameaux H, Brighton TA, Cohen AT, Davidson BL, Decousus H, Freitas MCS, Holberg G, Kakkar AK, Haskell L, van Bellen B, Pap AF, Berkowitz SD, Verhamme P, Wells PS, Prandoni P; EINSTEIN CHOICE Investigators.

N Engl J Med. 2017 Mar 30;376(13):1211-1222. doi: 10.1056/NEJMoa1700518. Epub 2017 Mar 18.


Platelet full length TFPI-α in healthy volunteers is not affected by sex or hormonal use.

Winckers K, Thomassen S, Ten Cate H, Hackeng TM.

PLoS One. 2017 Feb 3;12(2):e0168273. doi: 10.1371/journal.pone.0168273. eCollection 2017.


The use of regression analysis in determining reference intervals for low hematocrit and thrombocyte count in multiple electrode aggregometry and platelet function analyzer 100 testing of platelet function.

Kuiper GJAJM, Houben R, Wetzels RJH, Verhezen PWM, van Oerle R, Ten Cate H, Henskens YMC, Lancé MD.

Platelets. 2017 Jan 9:1-8. doi: 10.1080/09537104.2016.1257782. [Epub ahead of print]


Mean Platelet Volume and Arterial Stiffness - Clinical Relationship and Common Genetic Variability.

Panova-Noeva M, Arnold N, Hermanns MI, Prochaska JH, Schulz A, Spronk HM, Binder H, Pfeiffer N, Beutel M, Blankenberg S, Zeller T, Lotz J, Münzel T, Lackner KJ, Ten Cate H, Wild PS.

Sci Rep. 2017 Jan 6;7:40229. doi: 10.1038/srep40229.


Pre-analytical issues in the haemostasis laboratory: guidance for the clinical laboratories.

Magnette A, Chatelain M, Chatelain B, Ten Cate H, Mullier F.

Thromb J. 2016 Dec 12;14:49. doi: 10.1186/s12959-016-0123-z. eCollection 2016. Review.


Quality of Vitamin K Antagonist Control and 1-Year Outcomes in Patients with Atrial Fibrillation: A Global Perspective from the GARFIELD-AF Registry.

Haas S, Ten Cate H, Accetta G, Angchaisuksiri P, Bassand JP, Camm AJ, Corbalan R, Darius H, Fitzmaurice DA, Goldhaber SZ, Goto S, Jacobson B, Kayani G, Mantovani LG, Misselwitz F, Pieper K, Schellong SM, Stepinska J, Turpie AG, van Eickels M, Kakkar AK; GARFIELD-AF Investigators.

PLoS One. 2016 Oct 28;11(10):e0164076. doi: 10.1371/journal.pone.0164076. eCollection 2016.

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