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Investigating Immune Gene Signatures in Peripheral Blood from Subjects with Allergic Rhinitis Undergoing Nasal Allergen Challenge.

Kim YW, Singh A, Shannon CP, Thiele J, Steacy LM, Ellis AK, Neighbour H, Gliddon DR, Hickey PLC, Larché M, Tebbutt SJ.

J Immunol. 2017 Oct 18. pii: ji1700378. doi: 10.4049/jimmunol.1700378. [Epub ahead of print]


Differentiating heart failure phenotypes using sex-specific transcriptomic and proteomic biomarker panels.

Toma M, Mak GJ, Chen V, Hollander Z, Shannon CP, Lam KKY, Ng RT, Tebbutt SJ, Wilson-McManus JE, Ignaszewski A, Anderson T, Dyck JRB, Howlett J, Ezekowitz J, McManus BM, Oudit GY.

ESC Heart Fail. 2017 Aug;4(3):301-311. doi: 10.1002/ehf2.12136. Epub 2017 Mar 4.


Diagnosis of Western Red Cedar Asthma Using a Blood-based Gene Expression Biomarker Panel.

Yang CX, Singh A, Kim YW, Conway EM, Carlsten C, Tebbutt SJ.

Am J Respir Crit Care Med. 2017 May 2. doi: 10.1164/rccm.201608-1740LE. [Epub ahead of print]


Angiopoietin-like 4 Enhances the Proliferation and Migration of Tendon Fibroblasts.

Jamil S, Mousavizadeh R, Roshan-Moniri M, Tebbutt SJ, McCormack RG, Duronio V, Scott A.

Med Sci Sports Exerc. 2017 Sep;49(9):1769-1777. doi: 10.1249/MSS.0000000000001294.


Association of Serum MiR-142-3p and MiR-101-3p Levels with Acute Cellular Rejection after Heart Transplantation.

Sukma Dewi I, Hollander Z, Lam KK, McManus JW, Tebbutt SJ, Ng RT, Keown PA, McMaster RW, McManus BM, Gidlöf O, Öhman J.

PLoS One. 2017 Jan 26;12(1):e0170842. doi: 10.1371/journal.pone.0170842. eCollection 2017.


Enumerateblood - an R package to estimate the cellular composition of whole blood from Affymetrix Gene ST gene expression profiles.

Shannon CP, Balshaw R, Chen V, Hollander Z, Toma M, McManus BM, FitzGerald JM, Sin DD, Ng RT, Tebbutt SJ.

BMC Genomics. 2017 Jan 6;18(1):43. doi: 10.1186/s12864-016-3460-1.


SABRE: a method for assessing the stability of gene modules in complex tissues and subject populations.

Shannon CP, Chen V, Takhar M, Hollander Z, Balshaw R, McManus BM, Tebbutt SJ, Sin DD, Ng RT.

BMC Bioinformatics. 2016 Nov 14;17(1):460.


COPD Exacerbation Biomarkers Validated Using Multiple Reaction Monitoring Mass Spectrometry.

Leung JM, Chen V, Hollander Z, Dai D, Tebbutt SJ, Aaron SD, Vandemheen KL, Rennard SI, FitzGerald JM, Woodruff PG, Lazarus SC, Connett JE, Coxson HO, Miller B, Borchers C, McManus BM, Ng RT, Sin DD.

PLoS One. 2016 Aug 15;11(8):e0161129. doi: 10.1371/journal.pone.0161129. eCollection 2016.


Controlled diesel exhaust and allergen coexposure modulates microRNA and gene expression in humans: Effects on inflammatory lung markers.

Rider CF, Yamamoto M, Günther OP, Hirota JA, Singh A, Tebbutt SJ, Carlsten C.

J Allergy Clin Immunol. 2016 Dec;138(6):1690-1700. doi: 10.1016/j.jaci.2016.02.038. Epub 2016 Apr 24.


The Effect of Different Case Definitions of Current Smoking on the Discovery of Smoking-Related Blood Gene Expression Signatures in Chronic Obstructive Pulmonary Disease.

Obeidat M, Ding X, Fishbane N, Hollander Z, Ng RT, McManus B, Tebbutt SJ, Miller BE, Rennard S, Paré PD, Sin DD.

Nicotine Tob Res. 2016 Sep;18(9):1903-9. doi: 10.1093/ntr/ntw129. Epub 2016 May 6.


Interactions of Aspergillus fumigatus Conidia with Airway Epithelial Cells: A Critical Review.

Croft CA, Culibrk L, Moore MM, Tebbutt SJ.

Front Microbiol. 2016 Apr 7;7:472. doi: 10.3389/fmicb.2016.00472. eCollection 2016. Review.


Identifying Molecular Mechanisms of the Late-Phase Asthmatic Response by Integrating Cellular, Gene, and Metabolite Levels in Blood.

Singh A, Shannon CP, Kim YW, DeMarco ML, Gauvreau GM, FitzGerald JM, Boulet LP, O'Byrne PM, Le Cao KA, Tebbutt SJ.

Ann Am Thorac Soc. 2016 Mar;13 Suppl 1:S98. doi: 10.1513/AnnalsATS.201510-694MG.


Systems Biology Approaches for Host-Fungal Interactions: An Expanding Multi-Omics Frontier.

Culibrk L, Croft CA, Tebbutt SJ.

OMICS. 2016 Mar;20(3):127-38. doi: 10.1089/omi.2015.0185. Epub 2016 Feb 17. Review.


A Regulatory T-Cell Gene Signature Is a Specific and Sensitive Biomarker to Identify Children With New-Onset Type 1 Diabetes.

Pesenacker AM, Wang AY, Singh A, Gillies J, Kim Y, Piccirillo CA, Nguyen D, Haining WN, Tebbutt SJ, Panagiotopoulos C, Levings MK.

Diabetes. 2016 Apr;65(4):1031-9. doi: 10.2337/db15-0572. Epub 2016 Jan 19.


Impact of Statins on Gene Expression in Human Lung Tissues.

Lane J, van Eeden SF, Obeidat M, Sin DD, Tebbutt SJ, Timens W, Postma DS, Laviolette M, Paré PD, Bossé Y.

PLoS One. 2015 Nov 4;10(11):e0142037. doi: 10.1371/journal.pone.0142037. eCollection 2015.


The Effect of Statins on Blood Gene Expression in COPD.

Obeidat M, Fishbane N, Nie Y, Chen V, Hollander Z, Tebbutt SJ, Bossé Y, Ng RT, Miller BE, McManus B, Rennard S, Paré PD, Sin DD.

PLoS One. 2015 Oct 13;10(10):e0140022. doi: 10.1371/journal.pone.0140022. eCollection 2015.


Discovery of novel plasma protein biomarkers to predict imminent cystic fibrosis pulmonary exacerbations using multiple reaction monitoring mass spectrometry.

Quon BS, Dai DL, Hollander Z, Ng RT, Tebbutt SJ, Man SF, Wilcox PG, Sin DD.

Thorax. 2016 Mar;71(3):216-22. doi: 10.1136/thoraxjnl-2014-206710. Epub 2015 Mar 16.


Serum proteomics in multiple sclerosis disease progression.

Tremlett H, Dai DL, Hollander Z, Kapanen A, Aziz T, Wilson-McManus JE, Tebbutt SJ, Borchers CH, Oger J, Cohen Freue GV.

J Proteomics. 2015 Apr 6;118:2-11. doi: 10.1016/j.jprot.2015.02.018. Epub 2015 Mar 6.


Granzyme B mediates both direct and indirect cleavage of extracellular matrix in skin after chronic low-dose ultraviolet light irradiation.

Parkinson LG, Toro A, Zhao H, Brown K, Tebbutt SJ, Granville DJ.

Aging Cell. 2015 Feb;14(1):67-77. doi: 10.1111/acel.12298. Epub 2014 Dec 11.


Novel multivariate methods for integration of genomics and proteomics data: applications in a kidney transplant rejection study.

Günther OP, Shin H, Ng RT, McMaster WR, McManus BM, Keown PA, Tebbutt SJ, Lê Cao KA.

OMICS. 2014 Nov;18(11):682-95. doi: 10.1089/omi.2014.0062.

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