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Items: 1 to 20 of 98

1.

PRIMA-1Met suppresses colorectal cancer independent of p53 by targeting MEK.

Lu T, Zou Y, Xu G, Potter JA, Taylor GL, Duan Q, Yang Q, Xiong H, Qiu H, Ye D, Zhang P, Yu S, Yuan X, Zhu F, Wang Y, Xiong H.

Oncotarget. 2016 Dec 13;7(50):83017-83030. doi: 10.18632/oncotarget.12940.

2.

Erratum to: Structural characterization of the carbohydrate-binding module of NanA sialidase, a pneumococcal virulence factor.

Yang L, Connaris H, Potter JA, Taylor GL.

BMC Struct Biol. 2015 Oct 6;15:19. doi: 10.1186/s12900-015-0047-z. No abstract available.

3.

Streptococcus pneumoniae NanC: STRUCTURAL INSIGHTS INTO THE SPECIFICITY AND MECHANISM OF A SIALIDASE THAT PRODUCES A SIALIDASE INHIBITOR.

Owen CD, Lukacik P, Potter JA, Sleator O, Taylor GL, Walsh MA.

J Biol Chem. 2015 Nov 13;290(46):27736-48. doi: 10.1074/jbc.M115.673632. Epub 2015 Sep 14.

4.

Structural characterization of the carbohydrate-binding module of NanA sialidase, a pneumococcal virulence factor.

Yang L, Connaris H, Potter JA, Taylor GL.

BMC Struct Biol. 2015 Aug 20;15:15. doi: 10.1186/s12900-015-0042-4. Erratum in: BMC Struct Biol. 2015;15:19.

5.

Discovery of intramolecular trans-sialidases in human gut microbiota suggests novel mechanisms of mucosal adaptation.

Tailford LE, Owen CD, Walshaw J, Crost EH, Hardy-Goddard J, Le Gall G, de Vos WM, Taylor GL, Juge N.

Nat Commun. 2015 Jul 8;6:7624. doi: 10.1038/ncomms8624.

6.

Sialic acid-binding protein Sp2CBMTD protects mice against lethal challenge with emerging influenza A (H7N9) virus.

Govorkova EA, Baranovich T, Marathe BM, Yang L, Taylor MA, Webster RG, Taylor GL, Connaris H.

Antimicrob Agents Chemother. 2015 Mar;59(3):1495-504. doi: 10.1128/AAC.04431-14. Epub 2014 Dec 22.

7.

Prevention of influenza by targeting host receptors using engineered proteins.

Connaris H, Govorkova EA, Ligertwood Y, Dutia BM, Yang L, Tauber S, Taylor MA, Alias N, Hagan R, Nash AA, Webster RG, Taylor GL.

Proc Natl Acad Sci U S A. 2014 Apr 29;111(17):6401-6. doi: 10.1073/pnas.1404205111. Epub 2014 Apr 14.

8.

Kinetic and structural evaluation of selected active site mutants of the Aspergillus fumigatus KDNase (sialidase).

Yeung JH, Telford JC, Shidmoossavee FS, Bennet AJ, Taylor GL, Moore MM.

Biochemistry. 2013 Dec 23;52(51):9177-86. doi: 10.1021/bi401166f. Epub 2013 Dec 10.

PMID:
24295366
9.

Synthesis and structural characterisation of selective non-carbohydrate-based inhibitors of bacterial sialidases.

Brear P, Telford J, Taylor GL, Westwood NJ.

Chembiochem. 2012 Nov 5;13(16):2374-83. doi: 10.1002/cbic.201200433. Epub 2012 Oct 15.

PMID:
23070966
10.

Optimization of a direct spectrophotometric method to investigate the kinetics and inhibition of sialidases.

Hayre JK, Xu G, Borgianni L, Taylor GL, Andrew PW, Docquier JD, Oggioni MR.

BMC Biochem. 2012 Oct 2;13:19. doi: 10.1186/1471-2091-13-19.

11.

Toward a hepatitis C virus vaccine: the structural basis of hepatitis C virus neutralization by AP33, a broadly neutralizing antibody.

Potter JA, Owsianka AM, Jeffery N, Matthews DJ, Keck ZY, Lau P, Foung SK, Taylor GL, Patel AH.

J Virol. 2012 Dec;86(23):12923-32. doi: 10.1128/JVI.02052-12. Epub 2012 Sep 19.

12.

Results from an experimental trial at a Head Start center to evaluate two meal service approaches to increase fruit and vegetable intake of preschool aged children.

Harnack LJ, Oakes JM, French SA, Rydell SA, Farah FM, Taylor GL.

Int J Behav Nutr Phys Act. 2012 Apr 30;9:51. doi: 10.1186/1479-5868-9-51.

13.

Receptor-binding specificity of the human parainfluenza virus type 1 hemagglutinin-neuraminidase glycoprotein.

Alymova IV, Portner A, Mishin VP, McCullers JA, Freiden P, Taylor GL.

Glycobiology. 2012 Feb;22(2):174-80. doi: 10.1093/glycob/cwr112. Epub 2011 Aug 16.

14.

Structural basis for Streptococcus pneumoniae NanA inhibition by influenza antivirals zanamivir and oseltamivir carboxylate.

Gut H, Xu G, Taylor GL, Walsh MA.

J Mol Biol. 2011 Jun 17;409(4):496-503. doi: 10.1016/j.jmb.2011.04.016. Epub 2011 Apr 14.

PMID:
21514303
15.

The Aspergillus fumigatus sialidase is a 3-deoxy-D-glycero-D-galacto-2-nonulosonic acid hydrolase (KDNase): structural and mechanistic insights.

Telford JC, Yeung JH, Xu G, Kiefel MJ, Watts AG, Hader S, Chan J, Bennet AJ, Moore MM, Taylor GL.

J Biol Chem. 2011 Mar 25;286(12):10783-92. doi: 10.1074/jbc.M110.207043. Epub 2011 Jan 19.

16.

Three Streptococcus pneumoniae sialidases: three different products.

Xu G, Kiefel MJ, Wilson JC, Andrew PW, Oggioni MR, Taylor GL.

J Am Chem Soc. 2011 Feb 16;133(6):1718-21. doi: 10.1021/ja110733q. Epub 2011 Jan 18.

PMID:
21244006
17.

The Scottish Structural Proteomics Facility: targets, methods and outputs.

Oke M, Carter LG, Johnson KA, Liu H, McMahon SA, Yan X, Kerou M, Weikart ND, Kadi N, Sheikh MA, Schmelz S, Dorward M, Zawadzki M, Cozens C, Falconer H, Powers H, Overton IM, van Niekerk CA, Peng X, Patel P, Garrett RA, Prangishvili D, Botting CH, Coote PJ, Dryden DT, Barton GJ, Schwarz-Linek U, Challis GL, Taylor GL, White MF, Naismith JH.

J Struct Funct Genomics. 2010 Jun;11(2):167-80. doi: 10.1007/s10969-010-9090-y. Epub 2010 Apr 24.

18.

Introduction to phasing.

Taylor GL.

Acta Crystallogr D Biol Crystallogr. 2010 Apr;66(Pt 4):325-38. doi: 10.1107/S0907444910006694. Epub 2010 Mar 24.

19.

Insights into the biosynthesis of the Vibrio cholerae major autoinducer CAI-1 from the crystal structure of the PLP-dependent enzyme CqsA.

Jahan N, Potter JA, Sheikh MA, Botting CH, Shirran SL, Westwood NJ, Taylor GL.

J Mol Biol. 2009 Sep 25;392(3):763-73. doi: 10.1016/j.jmb.2009.07.042. Epub 2009 Jul 22.

PMID:
19631226
20.

Crystal structure of the Vibrio cholerae ferric uptake regulator (Fur) reveals insights into metal co-ordination.

Sheikh MA, Taylor GL.

Mol Microbiol. 2009 Jun;72(5):1208-20. doi: 10.1111/j.1365-2958.2009.06718.x. Epub 2009 Apr 28.

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