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Items: 1 to 20 of 349

1.

Silencing Of The Drosophila Ortholog Of Sox5 Leads To Abnormal Neuronal Development And Behavioral Impairment.

Li A, Hooli B, Mullin K, Tate RE, Bubnys A, Kirchner R, Chapman B, Hofmann O, Hide W, Tanzi RE.

Hum Mol Genet. 2017 Feb 10. doi: 10.1093/hmg/ddx051. [Epub ahead of print] No abstract available.

PMID:
28186563
2.

Drosophila Preparation and Longitudinal Imaging of Heart Function In Vivo Using Optical Coherence Microscopy (OCM).

Men J, Jerwick J, Wu P, Chen M, Alex A, Ma Y, Tanzi RE, Li A, Zhou C.

J Vis Exp. 2016 Dec 12;(118). doi: 10.3791/55002.

PMID:
28060288
3.

3D culture models of Alzheimer's disease: a road map to a "cure-in-a-dish".

Choi SH, Kim YH, Quinti L, Tanzi RE, Kim DY.

Mol Neurodegener. 2016 Dec 9;11(1):75. Review.

4.

Palmitoylated APP Forms Dimers, Cleaved by BACE1.

Bhattacharyya R, Fenn RH, Barren C, Tanzi RE, Kovacs DM.

PLoS One. 2016 Nov 22;11(11):e0166400. doi: 10.1371/journal.pone.0166400.

5.

Family-based association analyses of imputed genotypes reveal genome-wide significant association of Alzheimer's disease with OSBPL6, PTPRG, and PDCL3.

Herold C, Hooli BV, Mullin K, Liu T, Roehr JT, Mattheisen M, Parrado AR, Bertram L, Lange C, Tanzi RE.

Mol Psychiatry. 2016 Nov;21(11):1608-1612. doi: 10.1038/mp.2015.218.

6.

Optical Coherence Tomography for Brain Imaging and Developmental Biology.

Men J, Huang Y, Solanki J, Zeng X, Alex A, Jerwick J, Zhang Z, Tanzi RE, Li A, Zhou C.

IEEE J Sel Top Quantum Electron. 2016 Jul-Aug;22(4). pii: 6803213.

PMID:
27721647
7.

Corrigendum: Identification of Altered Metabolomic Profiles Following a Panchakarma-based Ayurvedic Intervention in Healthy Subjects: The Self-Directed Biological Transformation Initiative (SBTI).

Peterson CT, Lucas J, John-Williams LS, Thompson JW, Moseley MA, Patel S, Peterson SN, Porter V, Schadt EE, Mills PJ, Tanzi RE, Doraiswamy PM, Chopra D.

Sci Rep. 2016 Oct 10;6:34678. doi: 10.1038/srep34678. No abstract available.

8.

Identification of Altered Metabolomic Profiles Following a Panchakarma-based Ayurvedic Intervention in Healthy Subjects: The Self-Directed Biological Transformation Initiative (SBTI).

Peterson CT, Lucas J, John-Williams LS, Thompson JW, Moseley MA, Patel S, Peterson SN, Porter V, Schadt EE, Mills PJ, Tanzi RE, Doraiswamy PM, Chopra D.

Sci Rep. 2016 Sep 9;6:32609. doi: 10.1038/srep32609.

9.

Alzheimer's disease: the potential therapeutic role of the natural antibiotic amyloid-β peptide.

Kumar DK, Eimer WA, Tanzi RE, Moir RD.

Neurodegener Dis Manag. 2016 Oct;6(5):345-8. doi: 10.2217/nmt-2016-0035. No abstract available.

10.

Meditation and vacation effects have an impact on disease-associated molecular phenotypes.

Epel ES, Puterman E, Lin J, Blackburn EH, Lum PY, Beckmann ND, Zhu J, Lee E, Gilbert A, Rissman RA, Tanzi RE, Schadt EE.

Transl Psychiatry. 2016 Aug 30;6(8):e880. doi: 10.1038/tp.2016.164.

11.

Alzheimer's disease-associated TREM2 variants exhibit either decreased or increased ligand-dependent activation.

Song W, Hooli B, Mullin K, Jin SC, Cella M, Ulland TK, Wang Y, Tanzi RE, Colonna M.

Alzheimers Dement. 2016 Aug 9. pii: S1552-5260(16)30203-5. doi: 10.1016/j.jalz.2016.07.004. [Epub ahead of print]

PMID:
27520774
12.

Antibiotic-induced perturbations in gut microbial diversity influences neuro-inflammation and amyloidosis in a murine model of Alzheimer's disease.

Minter MR, Zhang C, Leone V, Ringus DL, Zhang X, Oyler-Castrillo P, Musch MW, Liao F, Ward JF, Holtzman DM, Chang EB, Tanzi RE, Sisodia SS.

Sci Rep. 2016 Jul 21;6:30028. doi: 10.1038/srep30028.

13.

Design and synthesis of aminothiazole modulators of the gamma-secretase enzyme.

Rynearson KD, Buckle RN, Barnes KD, Herr RJ, Mayhew NJ, Paquette WD, Sakwa SA, Nguyen PD, Johnson G, Tanzi RE, Wagner SL.

Bioorg Med Chem Lett. 2016 Aug 15;26(16):3928-37. doi: 10.1016/j.bmcl.2016.07.011.

PMID:
27426299
14.

The Self-Directed Biological Transformation Initiative and Well-Being.

Mills PJ, Wilson KL, Pung MA, Weiss L, Patel S, Doraiswamy PM, Peterson C, Porter V, Schadt E, Chopra D, Tanzi RE.

J Altern Complement Med. 2016 Aug;22(8):627-34. doi: 10.1089/acm.2016.0002.

PMID:
27351443
15.

Amyloid-β peptide protects against microbial infection in mouse and worm models of Alzheimer's disease.

Kumar DK, Choi SH, Washicosky KJ, Eimer WA, Tucker S, Ghofrani J, Lefkowitz A, McColl G, Goldstein LE, Tanzi RE, Moir RD.

Sci Transl Med. 2016 May 25;8(340):340ra72. doi: 10.1126/scitranslmed.aaf1059.

16.

Gain-of-function mutations in protein kinase Cα (PKCα) may promote synaptic defects in Alzheimer's disease.

Alfonso SI, Callender JA, Hooli B, Antal CE, Mullin K, Sherman MA, Lesné SE, Leitges M, Newton AC, Tanzi RE, Malinow R.

Sci Signal. 2016 May 10;9(427):ra47. doi: 10.1126/scisignal.aaf6209.

17.

Science Signaling Podcast for 10 May 2016: PKCα in Alzheimer's disease.

Newton AC, Tanzi RE, VanHook AM.

Sci Signal. 2016 May 10;9(427):pc11. doi: 10.1126/scisignal.aaf9436.

PMID:
27165779
18.

Relevance of the COPI complex for Alzheimer's disease progression in vivo.

Bettayeb K, Hooli BV, Parrado AR, Randolph L, Varotsis D, Aryal S, Gresack J, Tanzi RE, Greengard P, Flajolet M.

Proc Natl Acad Sci U S A. 2016 May 10;113(19):5418-23. doi: 10.1073/pnas.1604176113.

19.

Inhibition of death-associated protein kinase 1 attenuates the phosphorylation and amyloidogenic processing of amyloid precursor protein.

Kim BM, You MH, Chen CH, Suh J, Tanzi RE, Ho Lee T.

Hum Mol Genet. 2016 Jun 15;25(12):2498-2513.

PMID:
27094130
20.

Recapitulating amyloid β and tau pathology in human neural cell culture models: clinical implications.

Choi SH, Kim YH, D'Avanzo C, Aronson J, Tanzi RE, Kim DY.

US Neurol. 2015 Fall;11(2):102-105.

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